Medical and Surgical Management of Acute Disseminated Encephalomyelitis

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Title Medical and Surgical Management of Acute Disseminated Encephalomyelitis
Creator Brian D. Ellis, MD; Gregory S. Kosmorsky, DO; Bruce H. Cohen, MD
Affiliation Department of Ophthalmology, Cleveland Clinic Foundation, Ohio
Abstract Two children with a recent history of viral illness developed visual loss secondary to optic neuritis. Clinical findings and neuroimaging were consistent with acute disseminated encephalomyelitis (ADEM). Markedly elevated opening pressures were noted on lumbar puncture. The patients demonstrated an initial favorable response to high-dose corticosteroid administration. Both had recurrence of symptoms after being tapered off oral corticosteroids. High-dose corticosteroids were reinstituted and a bilateral optic nerve sheath decompression was performed on one patient who developed profound visual loss. A second patient underwent a lumboperitoneal shunt. Both children had resolution of their symptoms and had a recovery of normal visual acuity.
Subject Brain/pathology; Child, Preschool; Dexamethasone/administration & dosage; Dexamethasone/therapeutic use; Encephalomyelitis, Acute Disseminated/diagnosis; Encephalomyelitis, Acute Disseminated/therapy; Encephalomyelitis, Acute Disseminated/virology; Female; Humans; Magnetic Resonance Imaging; Optic Neuritis/diagnosis; Optic Neuritis/therapy; Optic Neuritis/virology; Ventriculoperitoneal Shunt; Virus Diseases/complications; Vision Disorders/etiology
OCR Text Show
Date 1994-12
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6tf33cr
Setname ehsl_novel_jno
ID 224530
Reference URL https://collections.lib.utah.edu/ark:/87278/s6tf33cr
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