| Identifier |
walsh_2014_s2_c4 |
| Title |
Its Dj Vu All Over Again |
| Creator |
Aileen A. Antonio-Santos, Yanny L. Phillips, Baha El Khatib, Howard T. Chang, David I. Kaufman, DO, Chair, Neurology & Ophthalmology, Michigan State University; Eric R. Eggenberger, DO, Mayo Clinic |
| Subject |
Erdheim-Chester disease; Glioblastoma Multiforme; Immunosuppression; Second Malignancy |
| History |
A 51-year-old male with a history of amblyopia OD presented in February 1999 with hyperemia, swelling and periorbital pain of the left eye. Visual acuity (VA) was 20/80 OD and 20/25 OS; color vision was 10/11 Ishihara plates OU, and Goldmann perimetry showed an inferior quadrantanopia OS. There was an RAPD OS, a comitant 15-prism diopter esotropia, and a 5-mm proptosis OS. Brain and orbits CT and MRI showed enhancing retrobulbar masses. CBC, CMP, ANA were normal. ESR was 53.Further diagnostic work-up was performed. |
| Disease/Diagnosis |
Erdheim-Chester disease and glioblastoma multiforme. |
| Presenting Symptom |
A 51-year-old male with a history of amblyopia OD presented in February 1999 with hyperemia, swelling and periorbital pain of the left eye. |
| Date |
2014-03 |
| References |
1. Chester W. Uber lipoidgranulomatose. Virchows Arch Pathol Anat. 1930; 279:561-602. 2. Drier A, et al. Cerebral, facial, and orbital involvement in Erdheim-Chester Disease: CT and MRI imaging fidings. Radiology. 2010 May;255:586-94. 3. Confavreux C, et al. Risk of Cancer from azathioprine therapy in multiple sclerosis: a case-control study. Neurology. 1996 Jun;46(6):1607-12. 4. Emile JF, Charlotte F, Amoura Z, Haroche J. BRAF mutations in Erdheim-Chester disease. J Clin Oncol. 2013 Jan;31(3):398. 5. Haroche J, et al. High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses. Blood. 2012 Sep;120(13):2700-3. Epub 2012 Aug 9. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Image |
| Source |
46th Annual Frank Walsh Society Meeting |
| Relation is Part of |
Case presented at the NANOS 2014 Walsh Session, March 2 |
| Collection |
Neuro-Ophthalmology Virtual Education Library - Walsh Session Annual Meeting Archives https://novel.utah.edu/Walsh/index3.html |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-6302 |
| Rights Management |
Copyright 2014. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6gx784x |
| Setname |
ehsl_novel_fbw |
| ID |
179186 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6gx784x |
