Title |
A Comparison of High Pressure Liquid Chromatography and Microbiological Assays for Ceftazidime |
Publication Type |
dissertation |
School or College |
College of Pharmacy |
Department |
Pharmacotherapy |
Author |
Ford, Dawn Callison |
Date |
1983-06 |
Description |
Ceftazidime is an investigational cephalosporin antibiotic with a broad spectrum of activity. In early in vitro studies, antibacterial activity has been demonstrated against most aeorbic gram-negative organism, including Pseudomonas aeriginosa. Before the pharmacokinetics of a new antibiotic such as ceftazidime can be adequately described, an accurate and reliable drug assay must be developed. Two methods currently available for ceftazidime determination include microbiological and high-pressure liquid chromatographic assays. The objective of this study was to compare the accuracy of an HPLC assay with a microbiological assay in the determination of a serum ceftazidime concentrations. |
Type |
Text |
Publisher |
University of Utah |
Subject |
Research Design; Ceftazidime; Anti-Bacterial Agents; Cephalosporins; Chromatography; High Pressure Liquid; Biological Assay |
Subject MESH |
Research Design; Ceftazidime; Anti-Bacterial Agents; Cephalosporins; Chromatography, High Pressure Liquid; Biological Assay; Agar; Culture Media; Microbial Sensitivity Tests; Pseudomonas; Pharmacokinetics; Comparative Study |
Dissertation Institution |
University of Utah |
Dissertation Name |
Doctor of Pharmacy |
Language |
eng |
Relation is Version of |
Digital version of A Comparison of High Pressure Liquid Chromatography and Microbiological Assays for Ceftazidime |
Rights Management |
Copyright © Dawn Callison Ford 1983 |
Format |
application/pdf |
Format Medium |
application/pdf |
Source |
Original in Marriott Library Special Collections |
ARK |
ark:/87278/s6g45540 |
Setname |
ir_etd |
ID |
195909 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6g45540 |