Idiopathic Intracranial Hypertension and Anemia: A Matched Case-Control Study

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Title Idiopathic Intracranial Hypertension and Anemia: A Matched Case-Control Study
Creator Gordon T. Plant; Sui H. Wong; Anna Sundholm; Susan P. Mollan
Affiliation Department of Neurology, University College London, London, United Kingdom; Department of Neuro-Ophthalmology, Moorfields Eye Hospital, Guys and St Thomas' NHSFT, London, United Kingdom; Department of Neurology, Karolinska University Hospital, Solna, Sweden; Department of Clincial Neuroscience, Karolinska Institute, Solna, Sweden; Department of Neuro-Ophthalmology, University Hospitals Birmingham, Birmingham, United Kingdom
Abstract Background: An association between idiopathic intracranial hypertension (IIH) and anemia has been speculated from previous case reports and case series. Retrospective studies to date have not used matched case controls to compare standardized complete blood count (CBC) values for the presence of anemia. Methods: At our tertiary care facility, 50 patients with IIH were matched with 50 case-control patients to compare CBC values from laboratory affiliates with standardized ranges. Results: No significant difference was found for any CBC parameters for IIH vs control patients. For female IIH and control patients as well as male IIH patients, values for red blood cell count, hemoglobin (HGB), and hematocrit (HCT) tended to trend on the lower end of 'normal' range, whereas this was not seen in male control patients. Conclusions: In this retrospective, matched case-control study, no significant association was found between IIH and anemia when comparing standardized CBC values. In accordance with previous studies, the prevalence of anemia may be relatively higher in the IIH population due to a prominent demographic overlap of females of child-bearing age.
Subject Anemia; Biomarker; Case-Control Studies; Follow-Up Studies; Hematocrit; Intracranial Pressure; Pseudotumor Cerebri; Retrospective Studies
OCR Text Show
Date 2021-06
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, June 2021, Volume 41, Issue 2
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s67bjnka
Setname ehsl_novel_jno
ID 1996603
Reference URL https://collections.lib.utah.edu/ark:/87278/s67bjnka
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