Investigating the Pathogenesis of Spaceflight Associated Neuroocular Syndrome with Headmounted Visualization Engineering of Pupil Reactivity

Update Item Information
Identifier 20230312_nanos_posters_098
Title Investigating the Pathogenesis of Spaceflight Associated Neuroocular Syndrome with Headmounted Visualization Engineering of Pupil Reactivity
Creator Prithul Sarker; Joshua Ong; Nasif Zaman; Sharif Amit Kamran; Ethan Waisberg; Phani Paladugu; Andrew Lee; Alireza Tavakkoli
Affiliation (PS) (NZ) (SAK) (AT) Human-Machine Perception Laboratory, Department of Computer Science and Engineering, University of Nevada, Reno, Reno, Nevada; (JO) Michigan Medicine, University of Michigan, Ann Arbor, Michigan; (EW) University College Dublin School of Medicine, Belfield, Dublin, Ireland; (PP) Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; (AL) Center for Space Medicine, Baylor College of Medicine, Houston, Texas; Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; The Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York; Department of Ophthalmology, University of Texas Medical Branch, Galveston, Texas; University of Texas MD Anderson Cancer Center, Houston, Texas; Texas A&M College of Medicine, Texas; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa
Subject High Intracranial Pressure/Headache; Pupil; Tumors; Trauma; Higher Visual Functions
Description Spaceflight associated neuro-ocular syndrome (SANS) refers to a collection of neuro-ophthalmic imaging and clinical findings observed in astronauts during and after long-duration spaceflight (LDSF) [1]. These findings include optic disc edema (ODE), posterior globe flattening, hyperopic refractive error shifts, and chorioretinal folds. Given its risk and consequence on vision and the neuro-ophthalmic system, NASA has deemed that mitigation of SANS is a top priority for a planetary mission to Mars [2]. While a physiological barrier to deep-space exploration, the pathogenesis of SANS is not well understood. Initially termed "Vision Impairment and Intracranial Pressure", it was initially thought that cephalad fluid shifts during spaceflight led to increased intracranial pressure (ICP) and subsequent SANS findings such as ODE. However, there are several discrepancies between terrestrial elevations of ICP and SANS including lumbar puncture opening pressure values in SANS astronauts post-flight which have been normal or only mildly elevated. However, given its invasive nature, lumbar punctures are not available during spaceflight [1].
Date 2023-03-14
Language eng
Format application/pdf
Type Text
Source 2023 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Poster Session I: New Diagnostic Measurement Techniques
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6w5pvtc
Setname ehsl_novel_nam
ID 2335304
Reference URL https://collections.lib.utah.edu/ark:/87278/s6w5pvtc
Back to Search Results