Identifier |
walsh_2001_s2_c2 |
Title |
Ataxic Optic Neuropathy |
Creator |
Madhav Thambisetty, MD, PhD; C. A. Scherzer; Z. Yu; V. A. Lennon; N. J. Newman |
Affiliation |
(MT) (CAS) (YZ) (VAL) (NJN) Emory Eye Center, Atlanta, GA |
Subject |
Gait Ataxia; Papilledema; Paraneoplastic Polyneuropathy; Nerve Tissue Proteins; Lung Neoplasms; Autoantibodies |
History |
A 72-year old female with a 5-month history of progressive, bilateral decline in visual acuity and gait ataxia. Previous history significant for depression, abdominal hysterectomy and bilateral carotid endarerectomy. Smoker. |
Pathology |
Bilateral optic neuropathy |
Disease/Diagnosis |
Small cell carcinoma of the lung |
Clinical |
VA: 20/400 OU; RAPD OS |
Presenting Symptom |
Progressive bilateral decline in visual acuity; Ataxic gait |
Neuroimaging |
CT |
Treatment |
Antineoplastic agents; Plasmapheresis |
Date |
2001 |
References |
1. Yu Z, Kryzer TJ, Griesmann GE, et al. CRMP-5 neuronal autuantibody: maker of lung care and thymoma related autoimmunity. Ann Neurol 2000. 2. Wang L-H, Strittmatter SM. A family of rat CRMP genes is differentially expressed in the nervous system. J Neuroscience 1996; 16(19):6197-6207. 3. Kamata T, Subleski M, Hara Y, et al. Isolation and characterization of a bovine neural specific protein (CRMP-2) cDNA homologous to unc-33, a C. elegans gene implicated in axonal outgrowth and guidance. Mol Brain Res 1998; 54:219-236. |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
27th Annual North American Neuro-Ophthalmology Society Meeting, Frank B. Walsh Session CD-ROM |
Relation is Part of |
Case 2, Session II, Walsh Session, NANOS 2001 |
Collection |
Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2008. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6ns0xk4 |
Setname |
ehsl_novel_fbw |
ID |
177713 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6ns0xk4 |