| Identifier |
walsh_2013_s1_c4 |
| Title |
A Wolf in Bear's Clothing |
| Creator |
Peter W. MacIntosh, Agatha Bogard, Pete Setabutr, Heather E. Moss |
| Subject |
Myeloid sarcoma; Abdominal mass; Orbital tumor; Child |
| History |
An eleven-month-old African-American girl with medical history of reactive airway disease developed a bump and bags under both eyes which her mother attributed to minor trauma. There were no signs of systemic illness. A week later, her mother noticed more prominent right eye edema and a new bump behind the right ear with crusting and tearing of the right eye. |
| Pathology |
Presentation and imaging were classic for metastatic neuroblastoma. |
| Disease/Diagnosis |
Myeloid Sarcoma |
| Clinical |
On exam, the patient averted to light and fixed and followed with either eye, pupils were equal, round and reactive to light; Right hypertropia with resistance to retropulsion; 2+ right lid edema and ptosis and trace left lid edema and ptosis; Abdominal exam revealed a right-sided mass; CT examination of the orbits revealed bilateral orbital and paranasal sinus masses with spiculations, calcifications and osseous destruction; MRI studies confirmed multiple T1 and T2 hypointense extra-axial masses of the calvarium, skull base and bones of the face, particularly involving the orbits, which enhanced with contrast and were slightly diffusion restricted; CT of the abdomen demonstrated right adrenal and rib masses |
| Presenting Symptom |
An eleven-month-old African-American girl with medical history of reactive airway disease developed a bump and bags under both eyes which her mother attributed to minor trauma. |
| Neuroimaging |
MRI |
| Date |
2013-02 |
| References |
1. Hmidi K, Zaouali S, Messaoud R, Mahjoub B, Ammari W, Bacha L, Laatriri A, Jenzeri S, Khairallah M. Bilateral orbital myeloid sarcoma as initial manifestation of acute myeloid leukemia. Int Ophthalmol, 27, 373-377, 2007. 2. Maka E, Lukats O, Toth J. Orbital tumour as initial manifestation of acute myeloid leukemia: granulocytic sarcoma: case report. Pathol Oncol Res, 14, 209-211, 2008. 3. Lee S, Park TS, Cheong J, Yang WI, Song J, Lee K, Kim J, Park Y, Choi J. Preceding orbital granulocytic sarcoma in an adult patient with acute myelogenous lenkemia with t(8;21): a case study and review of the literature. Cancer Genet Cytogenet, 185, 51-54, 2008. 4. Singh BK, Aleyas S, Hu Y, Zamkoff KW, Gladstone DE. Granulocytic sarcoma presenting as bilateral adrenal masses. Am J Hematol, 79, 73-75, 2005. 5. Johnston EL, Alonzo TA, Gerbing RB, Lange BJ, Woods WG. Superior outcome of pediatric acute myeloid leukemia pateints with orbital and CNS myeloid sarcoma: a report from the children's oncology group. Rediatr Blood Cancer, 58, 519-524, 2012. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
45th Annual Frank Walsh Society Meeting |
| Relation is Part of |
Case presented at the NANOS 2013 Walsh Session, February 10 |
| Collection |
Neuro-Ophthalmology Virtual Education Library - Walsh Session Annual Meeting Archives https://novel.utah.edu/Walsh/index3.html |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-6318 |
| Rights Management |
Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6w986sh |
| Setname |
ehsl_novel_fbw |
| ID |
179152 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6w986sh |
