Identifier |
20080311_nanos_posters_044.pdf |
Title |
Role of the Immune Modulator Programmed Cell Death-1 During Development and Apoptosis of Retinal Ganglion Cells |
Creator |
Gordon, Lynn; Chen, Ling; Braun, Jonathan |
Subject |
Retinal Ganglion Cells; Apoptosis; Programmed Cell Death-1; Retinal Development |
Description |
Retinal ganglion cell (RGC) death is a critical step in the development of the mature retina and formation of effective neuronal networks. Novel neuronal expression ofcertain canonical molecules of the immune system is directly linked to neural functions. Programmed cell death-1 (PD-1) is an important receptor molecule regulating cell-cell signaling and clonal fate in the irrunune system. Our previous data showed constitutive expression of PD-1 in the retina. We hypothesize that active negative selection of neurons through PD-1 pathway may be required in RGC culling. |
Date |
2008-03-11 |
Language |
eng |
Format |
application/pdf |
Format Creation |
application/pdf |
Type |
Text |
Source |
2008 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2008: Poster Presentations |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6g76m2w |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Contributor Secondary |
Steven Galetta, MD; Lynn Gordon, MD, PhD |
Setname |
ehsl_novel_nam |
ID |
180869 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6g76m2w |