Walsh & Hoyt: Neuroimaging Studies

Patients with typical MFS usually have normal imaging. However, in some patients, MR imaging shows abnormal signal, particularly in the brainstem, cerebellum, or both regions. As noted previously, MR imaging may also show enhancement of both affected and clinically normal cranial nerves. Occasionally, patients with MFS develop signs and symptoms of multiple sclerosis or a similar demyelinating process after apparent recovery from MFS. Whether the two conditions are related in some way is controversial, particularly considering the rarity of such a phenomenon.