| Identifier |
20070213_nanos_sciplatform_05.pdf |
| Title |
Quantitative Assessment of Normal and Hyperthyroid Extraocular Muscles in C57BL/6 Mice Using Confocal Laser Scanning Microscopy |
| Creator |
Swaraj Bose; Chyong Nien; Cristina Kenney; Douglas Wallace; James Jester |
| Affiliation |
University of California, lrvine, Irvine, California. |
| Subject |
Confocal Microscopy; Thyroid Eye Disease; Extraocular Muscles; Mitochondria; Experimental Hyperthyroidism |
| Description |
The study aims to determine if confocal laser scanning microscopy (CLSM) is able to distinguish structural and functional changes in extraocular muscles (EOMs) of hyperthyroid mice known to differ from normal controls. We employed CLSM on EOMs using two-photon excited fluorescence (TPEF), second-harmonic image microscopy (SHIM), mitotracker, JC-1 and FITC-phalloidin fluorescence staining to quantify and localize myofibrils, mitochondria, and actin-myosin complex abnormalities of EOMs. |
| Date |
2007-02-13 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2007 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS 2007: Scientific Platform Presentations (Session II) |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s65j0npd |
| Setname |
ehsl_novel_nam |
| ID |
180941 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s65j0npd |
