Progressive Visual Loss in a Man with Leukemia (Audio)

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Identifier walsh_2009_s1_c1_mp3
Title Progressive Visual Loss in a Man with Leukemia (Audio)
Creator Michael Lee Karen SantaCruz; Jeffrey Brace; Alexander Mckinney
Affiliation University of Minnesota, Minneapolis, MN
Subject Bone Marrow Transplantation; Myeloablative Agonists; Blindness, Cortical; Neurotoxicity Syndromes; Leukemia, Myeloid, Acute; Demyelinating Diseases
History A 48-year old male diagnosed with acute myeloid leukemia: Tx BMT.
Pathology White matter vacoulization, axonal spheroids, macrophages in medulla and spinal cord.
Disease/Diagnosis Neurotoxicity secondary to fludarabine administration
Clinical VA: Light perception OD,Hand motions OS
Presenting Symptom Blurred vision OS
Neuroimaging MRI
Treatment Myeloablative agonists
Date 2009-02
References 1. Ding X, Herzligh AA, et al. Ocular toxicity of fludarabine: a purine analog. Expert Rev Ophthalmol. 2008;3:97-109. 2. Chun HG, Leyland-Jones, BR, et al. Central nervous system toxicity of fludarabine phosphate. Cancer Treat Rep. 1986;70:1225-28. 3. Warrell RP, Berman E. Phase I and II study of fludarabine phosphate in leukemia: therapeutic efficacy with delayed central nervous system toxicity. J Clin Oncol. 1986;4:74-79. 4. Cheson BD, Vena DA, et al. Neurotoxicity of purine analogs: a review. J Clin Oncol 1 994; 12:2216-28.
Language eng
Format audio/mpeg
Type Sound
Source 41st Annual Frank Walsh Society Meeting
Relation is Part of NANOS Annual Meeting Frank B. Walsh Sessions; 2009
Collection Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2009. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6g73hmp
Setname ehsl_novel_fbw
ID 179069
Reference URL https://collections.lib.utah.edu/ark:/87278/s6g73hmp
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