Atypical Leber Hereditary Optic Neuropathy: 18 Year Interval Between Eyes

Update Item Information
Title Atypical Leber Hereditary Optic Neuropathy: 18 Year Interval Between Eyes
Creator Kaitlyn L. Ohden, BS; Peter H. Tang, MD, PhD; Chrystia C. Lilley, MD; Michael S. Lee, MD
Affiliation Department of Ophthalmology and Visual Neurosciences (KLO, PHT, CCL, MSL), University of Minnesota, Minneapolis, Minnesota
Abstract We describe a case of lymphocytic panhypophysitis (LPH) in a 30-year-old woman presenting with throbbing headaches and vision changes during her third trimester. LPH is the rarest subclassification of lymphocytic hypophysitis; it is typically found in males and has not previously been associated with pregnancy. Anterior and posterior pituitary deficits together with headaches should raise a high degree of suspicion regarding the possibility of LPH. The atypical magnetic resonance imaging finding of a heterogeneous pituitary mass additionally raised concern about pituitary apoplexy. Tissue from a transsphenoidal biopsy permitted diagnosis of lymphocytic hypophysitis. There was infiltration of the pituitary gland by small B and T lymphocytes. Resolution of the visual symptoms occurred after the biopsy and treatment with intravenous steroids.
Subject Biomedical Research; Databases, Factual; Eye Diseases; Humans; Neurology; Ophthalmology; Registries
OCR Text Show
Date 2016-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, September 2016, Volume 36, Issue 3
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s60s3hxw
Setname ehsl_novel_jno
ID 1276530
Reference URL https://collections.lib.utah.edu/ark:/87278/s60s3hxw
Back to Search Results