Considerations for the Treatment of Inflammatory Neuro-Ophthalmologic Disorders During the COVID-19 Pandemic

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Title Considerations for the Treatment of Inflammatory Neuro-Ophthalmologic Disorders During the COVID-19 Pandemic
Creator Yosbelkys Martin Paez; Jeffrey L. Bennett; Prem S. Subramanian; Victoria S. Pelak
Affiliation Departments of Ophthalmology (YMP, JLB, PSS, VSP), Neurology (YMP, JLB, PSS, VSP), and Neurosurgery (PSS), University of Colorado School of Medicine, Aurora, Colorado; and Programs in Neuroscience and Immunology (JLB), University of Colorado School of Medicine, Aurora, Colorado
Abstract The initiation and continuation of immune-based therapies to treat and prevent complications of inflammatory neuro-ophthalmologic disorders during the 2019 novel coronavirus (COVID-19) pandemic is the subject of considerable debate. In each case, a treatment decision must be reached based on best clinical practices for the disorder, patient comorbidities, the current state of knowledge about the pathogenesis and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the utilization of hospital and community resources. Unfortunately, the evidence needed to standardize the decision-making process for each neuro-ophthalmologic disorder is currently absent and is likely to require months or years to develop based on the accrual of robust international data sets. In this article, we review the current understanding of SARS-CoV-2 and COVID-19 complications to provide a framework for approaching the treatment of inflammatory neuro-ophthalmic disorders during the COVID-19 viral pandemic.
Subject Betacoronavirus; COVID-19; Coronavirus Infections / epidemiology; Coronavirus Infections / immunology; Eye Diseases / drug therapy; Giant Cell Arteritis / drug therapy; Humans; Immunomodulation; Immunosuppressive Agents / therapeutic use; Inflammation / drug therapy; Myasthenia Gravis / drug therapy; Nervous System Diseases / drug therapy; Optic Neuritis / drug therapy; Pandemics; Pneumonia, Viral / epidemiology; Pneumonia, Viral / immunology; SARS-CoV-2
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Date 2020-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Source Journal of Neuro-Ophthalmology, September 2020, Volume 40, Issue 3
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6gn3xn7
Setname ehsl_novel_jno
ID 1592954
Reference URL https://collections.lib.utah.edu/ark:/87278/s6gn3xn7
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