Rubidium and potassium concentrations in human blood and urine

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Title Rubidium and potassium concentrations in human blood and urine
Publication Type thesis
School or College School of Medicine
Department Physiology
Author Wood, Orin Lew
Contributor Wolfe, William T.; Sorensen, Wayne R.; Barber, David L. Jr.; Lloyd, Ray D.; Clark, David O.; Thurman, Gary B.
Date 1968-08
Description The naturally occurring rubidium and potassium concentrations wee measured in human plasma, erythrocytes and urine for normal, diseased and pregnant Utah subjects. The mean plasma Rb concentration in the normal adult subjects was 0.16 microgram/ml (y/ml) with a standard deviation (SD) of ±0.028 y/ml and the mean K concentration was 160 y/ml (±16.1 y/ml SD). The mean erythrocyte Rb concentration in the normal adult subjects was 1.18 y/ml (±0.623 y/ml SD) and the mean K concentration was 3840 y/ml (±142 y/ml SD). The mean urine Rb concentration in normal adult subjects was 1.52 y/ml (±0.549 y/ml SD) and the mean K concentration was 1910 y/ml (±581 y/ml SD). The Rb and K concentrations in the pregnant and diseased subjects did not vary significantly from the normal means. The mean estimated in Rb dietary intake rate for the normal adult subjects was 2.16 mg/d (±0.747 mg/d DS) and the estimated mean rate for K was 2.46 g/d (±0.040 g/d SD). The Adjusted Retentioin Ration (ARR), a ration of concentration ratios, was defined as AAR= (RB/K) Erythrocytes/(Rb/K)Excreta. The mean ARR for the normal adult subjects was 1.19 (±0.106 SD). A mean ARR > 1 indicates that Rb is preferentially retained in the erythrocyte compared to K when normalized for dietary intake. A subject with Duchenne muscular dystrophy had a ARR of 0.995 (±0.0694 SD). The estimated Rb whole-body burden in a normal 37 y old, 82 kg, 178 cm tall male was 0.28 g as calculated from 83Rb tracer measurements and the urine output rate of naturally occurring Rb. The Rb whole-body burden for a 15 y old, 69 kg, 140 cm tall male with Duchenne muscular dystrophy was 0.064 g.
Type Text
Publisher University of Utah
Subject MESH Rubidium; Potassium; Blood; Urine
Dissertation Institution University of Utah
Dissertation Name PhD
Language eng
Relation is Version of Digital reproduction of "Rubidium and potassium concentrations in human blood and urine" Spencer S. Eccles Health Sciences Library.
Rights Management © Orin Lew Wood.
Format application/pdf
Format Medium application/pdf
Format Extent 1,387,657 bytes
Identifier undthes,4016
Source Original: University of Utah Spencer S. Eccles Health Sciences Library (no longer available)
Master File Extent 1,387,691 bytes
ARK ark:/87278/s6jh3nz6
Setname ir_etd
ID 190920
Reference URL https://collections.lib.utah.edu/ark:/87278/s6jh3nz6
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