Acute Therapeutic Options for CRAO: To TPA or Not?

Update Item Information
Identifier 20230313_nanos_hottopics1_01
Title Acute Therapeutic Options for CRAO: To TPA or Not?
Creator Oana M. Dumitrascu, MD, MS
Affiliation Mayo Clinic, Scottsdale, AZ
Subject Central Retinal Artery Occlusion; Stroke; Thrombolysis; Alteplase
Description Alteplase is a tissue plasminogen activator (tPA) that received FDA approval in 1996 for the management of acute ischemic stroke in adults, for improving neurological recovery, and reducing the incidence of disability.
Date 2023-03
References 1. U.S. Food and Drug Administration. Drugs@FDA: FDA Approved Drug Products. Available at:; https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm. https://www.accessdata.fda.gov/drugsatfda_docs/nda/96/alteplase_toc.cfm 2. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995;333:1581-1587. 3. Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick JP,Brott T, Frankel M, Grotta JC, Haley EC Jr, Kwiatkowski T, Levine SR, Lewandowski C, Lu M, Lyden P, Marler JR, Patel S, Tilley BC, Albers G, Bluhmki E, Wilhelm M, Hamilton S; ATLANTIS Trials Investigators; ECASS Trials Investigators; NINDS rt-PA Study Group Investigators. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet.2004;363:768 -774. 4. Powers WJ, Rabinstein, Ackerson, Adeoye, Bambakidis, Becker, Biller, Brown, Demaerschalk, Hoh, Jauch, Chelsea S Kidwell, Thabele M Leslie-Mazwi, Bruce Ovbiagele, Phillip A Scott, Kevin N Sheth, Andrew M Southerland, Summers, Tirschwell. Guidelines for the Early Management of Patients with. Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2019 Dec;50(12):e344-e4185. Thomalla G, Simonsen CZ, Boutitie F, Andersen G, Berthezene Y, Cheng B, Cheripelli B, Cho TH, Fazekas F, Fiehler J, et al; WAKE-UP Investigators. MRI-guided thrombolysis for stroke with unknown time of onset. N Engl J Med. 2018;379:611-622.
Language eng
Format video/mp4
Type Image/MovingImage
Source 2023 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting 2023: Hot Topics: https://novel.utah.edu/collection/NAM/toc/
Collection Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2023. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6q444h8
Setname ehsl_novel_nam
ID 2385957
Reference URL https://collections.lib.utah.edu/ark:/87278/s6q444h8
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