Demographic Associations With Optic Neuritis Outcomes: An Analysis of the Optic Neuritis Treatment Trial

Poor visual recovery after optic neuritis is an important morbidity that affects activities of daily living and quality of life. Retrospective studies in the US, UK and South Africa have demonstrated disparate outcomes in individuals of African descent compared with Caucasians. However, published analyses of the prospectively collected Optic Neuritis Treatment Trial(ONTT) data did not find visual outcomes to be associated with race and ethnicity. We sought to further investigate demographic associations with visual outcomes following optic neuritis through application of longitudinal data analysis techniques to the ONTT data set.