Mitochondrial DNA evolution in the Nuu-chah-nulth population.

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Title Mitochondrial DNA evolution in the Nuu-chah-nulth population.
Publication Type thesis
School or College School of Medicine
Department Human Genetics
Author Valencia, Diana.
Date 1992-08
Description The first 400 base pairs of the mitochondrial DNA (mtDNA) control region were sequenced from 118 stored serum samples that belonged to different social bands of the Nuu-chah-nulth population. The sequences were used to calculate lineage divergence within and between social bands. The divergence values showed that the Nuu-chah-nulth bands were homogeneous, as evidenced by the amount of shared mtDNA lineages between the bands. When the mtDNA lineages were grouped by geographic regions (which also correspond with linguistic division), no relationship could be established. Also, despite the social organization of the Nuu-chah-nulth (matrilocal society), and mating preference (mating within bands) no relationship was found between lineage divergence and bands. Sixty-one polymorphic sites were identified in different regions in the mtDNA molecule from 60 nonrelated Nuu-chah-nulth. The sites were obtained by sequencing methods and by using restriction enzymes. The mtDNA lineages obtained from the different regions were used to estimate phylogenetic trees. Several inconsistencies were noted among the trees. Some of these could be explained by the different rates of evolution inside the mtDNA molecule. Therefore, the conclusion made from phylogenetic analysis should be draw with caution
Type Text
Publisher University of Utah
Subject Nootka Indians; Human Populatoin Genetics
Subject MESH Mitochondria; Genomics; Genomics; DNA; Indians, North American
Dissertation Institution University of Utah
Dissertation Name MS
Language eng
Relation is Version of Digital reproduction of "Mitochondrial DNA evolution in the Nuu-chah-nulth population." Spencer S. Eccles Health Sciences Library. Print version of "Mitochondrial DNA evolution in the Nuu-chah-nulth population." available at J. Willard Marriott Library Special Collection. QH9.7 1992 .V34.
Rights Management © Diana Valencia.
Format application/pdf
Format Medium application/pdf
Identifier us-etd2,45
Source Original: University of Utah Spencer S. Eccles Health Sciences Library (no longer available).
ARK ark:/87278/s6r78vtw
Setname ir_etd
ID 192914
Reference URL https://collections.lib.utah.edu/ark:/87278/s6r78vtw
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