| Identifier |
20130211_nanos_sciplatform1_07 |
| Title |
Intravitreal Injection Of Bevacizumab May Be Neuroprotective In A Mouse Model Of Optic Nerve Crush |
| Creator |
Daniel Rappoport; Dana Morzaev Morzaev; Shirel Weiss; Mark Vieyra; Hana Leiba; Nitza Goldenberg-Cohen |
| Affiliation |
(DR) (HL) Ophthalmology Department, Kaplan Medical Center, Rehovot, Israel; (DMM) (SW) (NGC) The Krieger Eye Research Laboratory, Felsenstein Medical Research Center, Petah Tiqwa, Israel; (DMM) (SW) (MV) (NGC) Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; (HL) Hadassah and Hebrew University Medical School, Jerusalem, Israel; (NGC) Pediatric Unit, Ophthalmology Department,Schneider Children's Medical Center of Israel, Petah Tiqwa, Israel |
| Subject |
Bevacizumab; Optic Neuropathy; Neuroprotective; Mouse Model |
| Description |
Disk edema may exacerbate axonal damage in acute optic neuropathy. Bevacizumab (Avastin) inhibits the signaling of Vascular Endothelial Growth Factor (VEGF), thereby potentially reducing the vasogenic edema of the disk. The aim of this study was to evaluate the effect of an intravitreal injection of bevazicumab on optic nerve edema and RGC loss in a mouse model of optic nerve crush (ONC). |
| Date |
2013-02-11 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2013 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS 2013: Platform Presentations (Session I) |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6tf341p |
| Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
| Setname |
ehsl_novel_nam |
| ID |
183436 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6tf341p |
