Identifier |
19840118_nanos_sciplatform1_06 |
Title |
Optic Nerve-Pettern Electroretinogram |
Creator |
Mark J. Kuppersmith |
Affiliation |
New York, New York |
Subject |
Optic Nerve; Pattern Electroretinogram; Optic Neuropathies; Tumors; Optic Neuritis |
Description |
Recently, the electroretinogram (ERG) recorded in response to patterned stimuli (PERG) were shown to be sensitive to pattern contrast and spatial frequency unlike the diffuse flash ERG. These findings coupled with experimental animal work suggest that the PERG reflects functioning of the ganglion cells which are the cell bodies of the axon of the optic nerve. Subjects with optic neuropathies should be ideally suited to this hypothesis. PERG, flash ERG, and visual evoked potentials (VEP) were studied in cases with unilateral optic nerve diseases secondary to tumors or optic neuritis. The PERG was absent in the affected eyes with poor acuity (less than 20/60) while the flash ERG was normal. A second group with acuity better than 20/40 showed reductions in the PERG amplitude of the affected compared to the normal eye. These interocular differences were especially marked when pattern contrast was reduced. Such results underscore the diagnostic value of the PERG in detecting mildly affected cases of optic nerve disease. These findings provide additional evidence regarding the ganglion cell origin of the PERG. |
Date |
1984-01-18 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
1984 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 1984: Platform Presentations (Session I) |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 1984. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s67h4r82 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Setname |
ehsl_novel_nam |
ID |
183634 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s67h4r82 |