Just the Two of Us

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Identifier walsh_2019_s3_c5
Title Just the Two of Us
Creator Dan Milea; Pratik Chougule; Ming Lee
Affiliation (DM) Singapore National Eye Centre, Singapore, Singapore; (PC) Singapore Eye Research Institute, Singapore, Singapore; (ML) Department of Anatomical Pathology, Singapore, Singapore
Subject Tumor; Optic Neuropathy; Metastatic Carcinoma; Optic Nerve; Compressive Optic Neuropathy
History A 63-year-old female patient of Chinese ethnicity was referred for unexplained visual loss in her right eye, discovered incidentally 1 month before presentation. Her past medical history revealed quiescent asthma and a benign cyst in the left lung, excised 27 years earlier. The patient had no vascular risk factors and was not smoking. On examination, best-corrected vision was counting fingers in the right eye and 6/7.5 in the left eye, associated with severe color vision loss in the right eye. There was a dense right relative afferent pupillary defect, but the remainder of the neuro-ophthalmic examination was normal, including fundoscopy, ocular motility and other cranial nerves functions. There was a dense visual field defect in the right eye and a Cirrus OCT disclosed normal retinal nerve fiber layer thickness in both eyes. The presumptive diagnosis was unexplained right retrobulbar optic neuropathy. A brain MRI disclosed an enhancing mass involving the anterior right clivus and apex, infiltrating the ipsilateral cavernous sinus, highly suggestive of meningioma. Excision of the tumor was decided by the neuro-surgical team, and pathology confirmed a WHO Grade III parapapillary chordoid meningioma. Post- operatively, the patient had an ispilateral iatrogenic pupil-involving 3rd nerve palsy, an ipsilateral 4th nerve palsy and developed a right soleal vein thrombosis, treated symptomatically. However, the patient's main post-operative complaint was persistent coughing.
Disease/Diagnosis Intra-meningioma tumor-to-tumor metastasis of previously undiagnosed lung adenocarcinoma.
Date 2019-03
References 1/ Sohail S, Karambizi DI, Baker A, Groh DM, Toms SA. A Comparative Report on Intracranial Tumor-to-Tumor Metastasis and Collision Tumors. World Neurosurgery 2018;116:454-463 2/ Caroli E, Salvati M, Giangaspero F, Ferrante L, Santoro A. Intrameningioma metastasis as first clinical manifestation of occult primary breast carcinoma. Neurosurg Rev 2006;29:49-54.
Language eng
Format video/mp4
Type Image/MovingImage
Source 2019 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS Annual Meeting Frank B. Walsh Sessions; 2019
Collection Neuro-Ophthalmology Virtual Education Library: Walsh Session Annual Meeting Archives: https://novel.utah.edu/Walsh/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6bw20sn
Setname ehsl_novel_fbw
ID 1431973
Reference URL https://collections.lib.utah.edu/ark:/87278/s6bw20sn
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