Identifier |
20120213_nanos_sciplatform_03 |
Title |
Aquaporumab: An Anti-Aquaporin-4 Monoclonal Antibody Blocker Therapy for Neuromyelitis Optica |
Creator |
Jeffrey Bennett; Lukmanee Tradtrantip; Hua Zhang; Samira Saadoun; Puay-Wah Phuan; Chiwah Lam; Marios Papadopoulos; Alan Verkman |
Affiliation |
(JB) (CL) University of Colorado Denver, Aurora, CO; (LT) (HZ) (PP) (AV) University of California, San Francisco, San Francisco, CA; (SS) (MP) St. George's, University of London, London, United Kingdom |
Subject |
Neuromyelitis Optica; Aquaporin-4; Therapy; Monoclonal Antibody |
Description |
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that predominantly affects the optic nerves and spinal cord. Circulating autoantibodies (NMO-IgG) against the astrocyte water channel aquaporin-4 (AQP4) cause complement- and cell-mediated astrocyte damage with consequent neuroinflammation and demyelination. |
Date |
2012-02-13 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2012 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS 2012: Scientific Platform Presentations (Session I) |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2012. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6dn7bjr |
Setname |
ehsl_novel_nam |
ID |
181984 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6dn7bjr |