In vitro analysis of antibiotic solutions and their effectiveness in inhibiting bacterial growth

Update Item Information
Title In vitro analysis of antibiotic solutions and their effectiveness in inhibiting bacterial growth
Publication Type thesis
School or College College of Nursing
Department Nursing
Author Cortez, Janet Frank
Date 1996-12
Description Within a limited time of excision and grafting autografts can be compromised or lost due to infection. An in vitro study was done to test susceptibility of four antibiotic solutions against the most common bacteria found in the University of Utah's Intermountain Burn Center. Cost analysis of each antibiotic solution was also addressed. Utilizing two rows of Whatman filter paper disks on four separate Mueller-Hinton agar plates, antibiotic solutions were applied in two volumes and placed in a 35°C incubator for 16 hours. Zones of inhibition were measured and 'susceptibility vs resistance' was determined. It was found that against Acinetobacter baumannii, Methicillin-resistant Staphylococcus aureus (MRSA), and Staphylococcus aureus, 25% Chlorhexidine Gluconate (Hibiclens) in sterile water, demonstrated superior susceptibility over 5% Mafenide Acetate (Sulfamylon), 1/4 strength Acetic Acid (AA) and TABI solutions (Bacitracin 10,000u/me, Neomycin 2%, Polymyxin 500,000u, 1/2cc Iodine in 1000ml saline). Pseudomonas aeruginosa was most susceptible to AA solution followed by Sulfamylon. Patient charges for 24-hours utilization of solution showed AA as the least expensive followed by Hibiclens, TABI and Sulfamylon.
Type Text
Publisher University of Utah
Subject Antibiotics; Therapy; Grafting; Universtiy of Utah's Intermountain Burn Center
Subject MESH Burns; Antibiotics, Combined; Graft vs Host Disease
Dissertation Institution University of Utah
Dissertation Name MS
Language eng
Relation is Version of Digital reproduction of "In vitro analysis of antibiotic solutions and their effectiveness in inhibiting bacterial growth". Spencer S. Eccles Health Sciences Library. Print version of "In vitro analysis of antibiotic solutions and their effectiveness in inhibiting bacterial growth". available at J. Willard Marriott Library Special Collection. RM31.5 1996 .C67.
Rights Management © Janet Frank Cortez.
Format application/pdf
Format Medium application/pdf
Format Extent 605,526 bytes
Identifier undthes,4475
Source Original: University of Utah Spencer S. Eccles Health Sciences Library (no longer available).
Master File Extent 605,578 bytes
ARK ark:/87278/s6833trz
Setname ir_etd
ID 190720
Reference URL https://collections.lib.utah.edu/ark:/87278/s6833trz
Back to Search Results