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Title | Creator | Description | Identifier |
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Development of a Retinal Ganglion Cell Specific Gene Therapy Using SIRT1 Signaling for Neuro-Protection (Video) | Ahmara G. Ross, Devin McDougald, Reas Khan, Thu Duong, Kimberly Dine, Puya Aravand, Natalia Tavares, Jean Bennett, Kenneth Shindler | Loss of retinal ganglion cells (RGC) can occur by trauma, inflammatory, and ischemia leading to irreversible effects upon vision. Sirtuin 1 (SIRT1) deacetylase has demonstrated therapeutic value in multiple models of optic neuropathy with small molecule biologics. The initial use of gene therapy... | 20200310_nanos_sciplatform3_04 |
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Development of a Retinal Ganglion Cell Specific Gene Therapy Using SIRT1 Signaling for Neuro-Protection (Slides) | Ahmara G. Ross, Devin McDougald, Reas Khan, Thu Duong, Kimberly Dine, Puya Aravand, Natalia Tavares, Jean Bennett, Kenneth Shindler | Loss of retinal ganglion cells (RGC) can occur by trauma, inflammatory, and ischemia leading to irreversible effects upon vision. Sirtuin 1 (SIRT1) deacetylase has demonstrated therapeutic value in multiple models of optic neuropathy with small molecule biologics. The initial use of gene therapy... | 20200310_nanos_sciplatform3_04-slides |
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Development of a Retinal Ganglion Cell Specific Gene Therapy Using SIRT1 Signaling for Neuro-Protection (PDF) | Ahmara G. Ross, Devin McDougald, Reas Khan, Thu Duong, Kimberly Dine, Puya Aravand, Natalia Tavares, Jean Bennett, Kenneth Shindler | Loss of retinal ganglion cells (RGC) can occur by trauma, inflammatory, and ischemia leading to irreversible effects upon vision. Sirtuin 1 (SIRT1) deacetylase has demonstrated therapeutic value in multiple models of optic neuropathy with small molecule biologics. The initial use of gene therapy... | 20200310_nanos_sciplatform3_04-pdf |