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Leber Hereditary Optic Neuropathy: from Bedside to Bench to Bedside | Nancy J. Newman, MD | This lecture will trace the story of our growing understanding of Leber hereditary optic neuropathy (LHON) from clinical recognition, to the first demonstration of a point mutation in the mitochondrial DNA associated with a human disease, to ground-breaking attempts at gene therapy. Upon completion ... | 20190320_nanos_jacobsonlecture1_01 |