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1 Long Term Treatment with Idebenone in Leber's Hereditary Optic Neuropathy (LHON): Real World Clinical PracticeXavier Llòria, Claudia Catarino, Magda Silva, Bettina von Livonius, Constanze Gallenmüller, Felice Lob, Günther Rudolph, Oskars Mikazans, Thomas KlopstockLHON is caused by mitochondrial DNA (mtDNA) mutations, resulting in progressive bilateral, severe central blindness. Idebenone (900 mg/day) is approved for use in LHON in the EU . We report long-term treatment outcomes in real-world clinical practice from a multicenter Expanded Access Program.20180306_nanos_posters_152
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