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1 SIRT1 Reduces Oxidative Stress and Delays RGC Loss Following Optic Nerve CrushShindler, Kenneth S; Zuo, Ling; Khan, Reas S; Dine, Kimberly; Wu, WenSIRT1 activation prevents loss of retinal ganglion cells (RGCs) in experimental optic neuritis. While the mechanism of this effect is unknown, a role in reduction of oxidative stress has been suggested. Because oxidative stress is a common mechanism of neuronal damage, we hypothesized that SIRT1 may...20130212_nanos_sciplatform2_06
2 SIRT1 Reduces Oxidative Stress and Delays RGC Loss Following Optic Nerve CrushShindler, Kenneth S; Zuo, Ling; Khan, Reas S; Dine, Kimberly; Wu, WenSIRT1 activation prevents loss of retinal ganglion cells (RGCs) in experimental optic neuritis. While the mechanism of this effect is unknown, a role in reduction of oxidative stress has been suggested. Because oxidative stress is a common mechanism of neuronal damage, we hypothesized that SIRT1 may...20130212_nanos_sciplatform2_06-1
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