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201 Systemic Disorders With Optic Nerve and Retinal FindingsLarry P. Frohman, MDThis 1-year-old child with familial erythrophagocytic lymphohistiocytosis was readmitted with a fever and was noted to have bilateral blindness. The spinal tap showed a protein of 148, with 178 WBC with 98% ""lymphocytes."" This MRI image demonstrates the optic nerve infiltration. He was treated wit...
202 Orbital TumorsLarry P. Frohman, MDThis 30-year-old man had a retrobulbar intraconal mass OS. The CT scans showed a heterogeneous lobulated enhancing mass, 2.2 x 1.9 x 1.8 cm. The case beautifully exhibits chorodial folds. The ultrasound showed internal reflectivity. The patient refused surgery. Pair with Images 97_60, 97_61, 97_62, ...
203 Orbital TumorsLarry P. Frohman, MDThis 30-year-old man had a retrobulbar intraconal mass OS. The CT scans showed a heterogeneous lobulated enhancing mass, 2.2 x 1.9 x 1.8 cm. The case beautifully exhibits chorodial folds. The ultrasound showed internal reflectivity. The patient refused surgery. Pair with Images 97_60, 97_61, 97_62, ...
204 Isolated Congenital Optic Disc AnomaliesLarry P. Frohman, MDThis 63-year-old man with amblyopia OD was seen for a question of ischemic optic neuropathy with a pale, swollen disc OD. The correct diagnosis is an exophytic capillary angioma of the optic nerve head. Disease/Diagnosis: Capillary Angioma.
205 Neuro-Ophthalmic Imaging-CT ScanLarry P. Frohman, MDThis patient was assaulted with a blunt object and suffered acute blindness due to traumatic optic neuropathy. Note how the lateral orbital wall has been fractured and displaced posteromedially into the region of the anterior optic canal.
206 Optic Tract Syndrome Due to Carotid Artery DolichoectasiaLarry P. Frohman, MDThis 43-year-old man was referred for evaluation of 6 months of visual loss OU. In retrospect, he had noticed increasing difficulty with his tennis game dating back over 3 years, as balls would pass him unexpectedly when hit to his backhand (left) side. The patient did not think this was progressive...
207 Optic Tract Syndrome Due to Carotid Artery DolichoectasiaLarry P. Frohman, MDThis 43-year-old man was referred for evaluation of 6 months of visual loss OU. In retrospect, he had noticed increasing difficulty with his tennis game dating back over 3 years, as balls would pass him unexpectedly when hit to his backhand (left) side. The patient did not think this was progressive...
208 Optic Tract Syndrome Due to Carotid Artery DolichoectasiaLarry P. Frohman, MDThis 43-year-old man was referred for evaluation of 6 months of visual loss OU. In retrospect, he had noticed increasing difficulty with his tennis game dating back over 3 years, as balls would pass him unexpectedly when hit to his backhand (left) side. The patient did not think this was progressive...
209 Systemic Disorders With Optic Nerve and Retinal FindingsLarry P. Frohman, MDThis 8-year-old girl had a history of acute lymphoblastic leukemia with neurologic involvement, with remission induced with radiation and chemotherapy. Her relapse showed as an isolated optic neuropathy with this fundus appearance. The other eye was normal. The MRI and spinal tap at this point were ...
210 Systemic Disorders With Optic Nerve and Retinal FindingsLarry P. Frohman, MDA 29-year-old African American woman presented with headaches, bilateral transient visual obscurations, blurred vision, numbness, and weakness of the lower extremities with myalgia and joint pains. She had an unplanned 12-pound weight loss over 2 months. A neurologist and internist diagnosed her wit...
211 Systemic Disorders With Optic Nerve and Retinal FindingsLarry P. Frohman, MDA 42-year old woman presented with a history of severe brow pain and 4 days of progressive visual loss OD. There was no increased pain on ocular rotation. Aside from heavy menses, she denied any significant past medical history. Her examination revealed acuity NLP OD, 20/25 OS; color vision 9/10 OS;...
212 Magnetic Resonance Imaging in Detection of Extracranial Internal Carotid Artery DissectionMarilyn C. Kay, MDThis 28-year-old woman presented with a 4-week history of bilateral visual loss. She had a known history of multiple sclerosis. Her vision was 20/60 OD and 20/40 OS, with an RAPD OS and optic pallor OU. Her fields and MRI are shown. Optic tract lesions usually result in an incongruous homonymous hem...
213 Neuro-Ophthalmic Case With Notable Field ChangesMarilyn C. Kay, MDThis 28-year-old woman presented with a 4-week history of bilateral visual loss. She had a known history of multiple sclerosis. Her vision was 20/60 OD and 20/40 OS, with an RAPD OS and optic pallor OU. Her fields and MRI are shown. Optic tract lesions usually result in an incongruous homonymous hem...
214 Neuro-Ophthalmic Imaging-Cerebral AngiographyMark J. Kupersmith, MDEhlers-Danlos syndrome is a connective tissue disorder that may affect blood vessels and predispose some affected patients to development of carotid cavernous fistula. Most patients with high-flow direct carotid cavernous sinus fistulas have suffered acute traumatic tears in the internal carotid art...
215 Neuro-Ophthalmic Consequences of TherapyMark J. Kupersmith, MDradiation retinopathy may mimic diabetic or hypertensive optic neuropathy. A history of irradiation to the eye, orbit, or head is mandatory. Radiation retinopathy usually occurs many months after radiation therapy.
216 Neuro-Ophthalmic Consequences of TherapyMark J. Kupersmith, MDradiation retinopathy may mimic diabetic or hypertensive optic neuropathy. A history of irradiation to the eye, orbit, or head is mandatory. Radiation retinopathy usually occurs many months after radiation therapy.
217 Neuro-Ophthalmic Consequences of TherapyMark J. Kupersmith, MDradiation retinopathy may mimic diabetic or hypertensive optic neuropathy. A history of irradiation to the eye, orbit, or head is mandatory. Radiation retinopathy usually occurs many months after radiation therapy.
218 Neuro-Ophthalmic Consequences of TherapyMark J. Kupersmith, MDRadiation causes a vascular retinopathy that may mimic diabetic or hypertensive retinopathy. It does not develop until many months or several years after radiation therapy to the eye, orbit or head.
219 Neuro-Ophthalmic Vascular DiseaseMark J. Kupersmith, MDAneurysms of the intracranial circulation may act as mass lesions and compress the afferent of efferent visual pathway. Ophthalmic artery aneurysms may compress the optic nerve and result in an optic neuropathy (ie, visual loss, afferent pupillary defect, optic atrophy). Treatment includes endovascu...
220 Neuro-Ophthalmic Vascular DiseaseMark J. Kupersmith, MDAneurysms of the intracranial circulation may act as mass lesions and compress the afferent of efferent visual pathway. Ophthalmic artery aneurysms may compress the optic nerve and result in an optic neuropathy (ie, visual loss, afferent pupillary defect, optic atrophy). Treatment includes endovascu...
221 Isolated Optic Neuritis/NeuropathyMark J. Kupersmith, MDPapilledema may produce visual loss due to chronic atrophic papilledema, secondary macular hemorrhage, exudate or edema, secondary ischemic optic neuropathy, or secondary subretinal neovascular membrane formation. Patients with papilledema and visual loss should be suspected of harboring one of thes...
222 Isolated Optic Neuritis/NeuropathyMark J. Kupersmith, MDPapilledema may produce visual loss due to chronic atrophic papilledema, secondary macular hemorrhage, exudate or edema, secondary ischemic optic neuropathy, or secondary subretinal neovascular membrane formation. Patients with papilledema and visual loss should be suspected of harboring one of thes...
223 Systemic Disorders With Optic Nerve and Retinal FindingsMark J. Kupersmith, MDSarcoidosis is an inflammatory granulomatous disease that may result in inflammatory or infiltrative optic neuropathology or retinal vasculitis. Pair with 91_34.
224 Systemic Disorders With Optic Nerve and Retinal FindingsMark J. Kupersmith, MDSarcoidosis is an inflammatory granulomatous disease that may result in inflammatory or infiltrative optic neuropathology or retinal vasculitis. Pair with 91_35.
225 Systemic Disorders With Optic Nerve and Retinal FindingsMark J. Kupersmith, MDSarcoidosis is an inflammatory multisystem granulomatous disease that may result in an inflammatory or infiltrative optic neuropathy, papilledema from increased intracranial pressure due to meningeal inflammation or intracranial granuloma, or may present with an optic disc granuloma. Pair with 91_31...
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