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201 Couldwell, William T.; Orlandi, Richard R.; Jensen, Randy L.Endoscopic-assisted craniofacial resection of esthesioneuroblastoma: minimizing facial incisionsThe surgical management of esthesioneuroblastomas has traditionally been craniofacial resection, which combines a bifrontal craniotomy with a transfacial approach. The latter usually involves a disfiguring facial incision, mid-facial degloving, lateral rhinotomy, and/or extensive facial osteotomies...Esthesioneuroblastoma; Craniofacial resection; Endoscope; Craniofacial surgery; Minimally invasive2003
202 Digre, Kathleen B.; Mamalis, Nick; White, George L. Jr.Congenital anomalies of the optic nerve in one family.We present three cases of congenital optic disc anomalies in one family who underwent an extensive diagnostic workup to exclude any intracranial pathology. One patient had elevated optic nerve heads and was hospitalized for multiple diagnostic tests including a lumbar puncture and magnetic resonance...Optic Nerve; Congenital Anomalies1992-04-24
203 Couldwell, William T.Immunology and immunotherapy of intrinsic glial tumorsImmunological aspects of glial neoplasms have been actively investigated for the past several years with particular focus on academic, diagnostic, and therapeutic objectives. As more knowledge is acquired about the cellular events relating to tumor behavior the more it appears that the immune system...Immunology; Glial tumors1990
204 Kestle, John R. W.It's randomized and double blinded... what more do we want?This issue of Journal of Neurosurgery: Pediatrics presents a randomized trial in which investigators have evaluated antimicrobial suture (AMS) in the prevention of shunt infection. The authors randomized 84 shunt procedures in 61 patients over 21 months. The surgeons and patients were blinded to...2008
205 Couldwell, William T.Use of cylindrical titanium mesh and locking plates in anterior cervical fusionAfter performing anterior cervical corpectomy or discectomy for cervical spondolytic myelopathy or radiculopathy, iliac crest bone graft and fibular auto- or allograft is often used to achieve arthrodesis in the cervical spine. The purpose of this study was to evaluate the use of a cylindrical titan...Anterior cervical fusion; Arthrodesis; Cylindrical titanium mesh; Lordosis; Kyphosis2001
206 Couldwell, William T.Increasing exposure of the petrous internal carotid artery for revascularization using the transzygomatic extended middle fossa approach: a cadaveric morphometric studyWhen internal carotid artery (ICA) sacrifice is planned in the management of difficult tumors or aneurysms at the cranial base, the petrous ICA may be a useful site for anastomosis for interpositional vascular bypass. However, exposure of the artery and performing an anastomosis in this region may...Revascularization; Internal carotid artery; Cranial base tumors; Giant aneurysms; Interpositional bypass; Surgical approach; Middle fossa2006
207 Couldwell, William T.Comment on Kitano, M., et al.: Subdural patch graft technique for watertight closure of large dural defects in extended transsphenoidal surgeryAhn and Kim demonstrate a suturing technique to close dural defects after transsphenoidal and extended transsphenoidal approaches. The technique entails a specifically designed forceps to cinch the knot down in the depths of the field. The Author's used the technique in 21 consecutive patients (16 e...Transsphenoidal surgery; CSF leaks2009
208 Kestle, John R. W.Comparison between magnetic resonance imaging and computed tomography for stereotactic coordinate determinationThe spatial accuracy of magnetic resonance imaging (MRI) has not been established for stereotactic surgery. Magnetic susceptibility artifacts may lead to anatomical distortion and inaccurate stereotactic MRI coordinates, especially when targets are in regions of the brain out of the center of the ma...Computed tomography; Stereotactic coordinates; Stereotactic surgery1992
209 Schmidt, Meic H.; Apfelbaum, Ronald I.Cervical spinal metastasis: anterior reconstruction and stabilization techniques after tumor resectionObject. In a review of the literature, the authors provide an overview of various techniques that have evolved for reconstruction and stabilization after resection for metastatic disease in the subaxial cervical spine. Methods. Reconstruction and stabilization of the cervical spine after vertebral...Cervical spine reconstruction; Metastasis; Spine tumor; Corpectomy; Stabilization technique; Vertebral body2003
210 Couldwell, William T.Simple closure following transsphenoidal surgeryThe most common nonendocrine complication after transsphenoidal surgery is cerebrospinal fluid (CSF) leak. Many neurosurgeons have advocated the routine reconstruction of the floor of the sella turcica using autologous fat, muscle, fascia, and either cartilage or bone after transsphenoidal surgery t...2006
211 Couldwell, William T.Total intravenous anesthesia: advantages for intracranial surgeryAlthough volatile anesthetics have been widely accepted in anesthetic management for neurosurgery, they reduce vascular resistance, resulting in increased cerebral blood flow and increased intracranial pressure (ICP). In patients with elevated ICP who undergo craniotomy, the increase in ICP during s...Anesthesia; Inhalants; Intravenous; Propofol; Intracranial surgery2007
212 Couldwell, William T.; Chin, Steven S.Extranodal NK/T-cell lymphoma presenting as a pituitary massExtranodal NK/T-cell lymphomas are uncommon neoplasms that are highly aggressive and show a strong association with Epstein-Barr virus. They most commonly affect the nasal cavity and paranasal sinuses; manifestation as a primary pituitary tumor has never been described. The authors report a case of ...2007-09
213 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 7: intractable low-back pain without stenosis or spondylolisthesisStandards. Lumbar fusion is recommended as a treatment for carefully selected patients with disabling lowback pain due to one- or two-level degenerative disease without stenosis or spondylolisthesis. Guidelines. There is insufficient evidence available to support a treatment guideline. Options. An...Fusion; Lumbar spine; Degenerative disease; Low back pain2005
214 Couldwell, William T.Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C systemThe protein kinase-C (PKC) second messenger system contributes to regulation of cell growth and differentiation. This study was undertaken to examine the effects of modulators of the PKC enzyme system on the state of differentiation and proliferation rates of human gliomas in vitro. The administrat...Protein kinase C; Phorbol ester; Cell proliferation; Tumor cell growth; Astrocyte; Glioma; Immunohistochemistry1990
215 Schmidt, Meic H.Benzoporphyrin derivative and light-emitting diode for use in photodynamic therapy: applications of space light-emitting diode technologyPhotodynamic therapy (PDT) is a cancer treatment modality that recently has been applied as adjuvant therapy for rain tumors. PDT consists of intravenously injecting a photosensitizer, which preferentially accumulates in tumor ells, into a patient and then activating the photosensitizer with a light...Benzoporphyrin; Photodynamic therapy; Brain tumors; Photofrin1998
216 Digre, Kathleen B.; Schmidt, Richard H.; Osborne, Anne G.; Patel, Bhupendra C.; Pratt, David; Rietz, Lisa A.Compressive optic neuropathy caused by renal osteodystrophy. Case report.Compressive optic neuropathy with acute or chronic vision loss has been associated with various skull base tumors, aneurysms, Graves disease, trauma, and, less commonly, fibrous dysplasia and osteopetrosis. The Author's present a case of acute visual deterioration in a 25-year-old woman who had mass...Optic Neuropathy; Optic Nerve Decompression; Renal Osteodystrophy2001-10
217 Dailey, Andrew T.Risk factors for respiratory failure following operative stabilization of thoracic and lumbar spine fracturesBackground: Respiratory failure is a serious complication that can adversely affect the hospital course and survival of multiply injured patients. Some studies have suggested that delayed surgical stabilization of spine fractures may increase the incidence of respiratory complications. However, the...Respiratory failure; Operative stabilization; Thoracic spine; Lumbar spine2006
218 Kestle, John R. W.Moyamoya phenomenon after radiation for optic gliomaThe role of radiotherapy in the management of patients with optic pathway glioma is controversial. In a series of patients with optic pathway glioma treated at The Hospital for Sick Children in Toronto, five children were encountered who developed moyamoya phenomenon after radiotherapy. A retrospec...Optic pathway glioma1993
219 Couldwell, William T.; Orlandi, Richard R.; Apfelbaum, Ronald I.Novel closure technique for the endonasal transsphenoidal approach: Technical noteTranssphenoidal microsurgery has been the standard approach to sellar lesions since the repopularization of the technique with modifications by Dott, Guiot, and Hardy. The endonasal transseptal transsphenoidal approach, as introduced by Hirsch, is still commonly used by pituitary surgeons to remove ...2004
220 Couldwell, William T.Pituitary apoplexy: diagnosis and managementPituitary apoplexy, an uncommon complication of pituitary adenomas, was first decribed in 1898 when pearce Bailey reported hemorrhage into a pituitary adenoma in a 50 year old man with acromegaly. The patient presented with sudden onset of headache, nausea, vomiting, fever, oculomotor palsies, and v...Pituitary Apoplexy; Pituitary adenoma; Transsphenoidal surgery2003
221 Schmidt, Meic H.Role of light-emitting diodes for photodynamic therapy of brain tumorsThe development of more effective light sources for Photodynamic Therapy (PDT) of brain tumors would be of benefit for both research and clinical application. In this study, the use of light-emitting diode arrays for PDT of brain tumors with Photofrin® porfimer sodium was investigated. An inflatabl...Aluminum Gallium Arsenide; Photodynamic therapy; Brain tumors; Photofrin1996
222 Kestle, John R. W.Lack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trialObject. Endoscopically assisted ventricular catheter placement has been reported to reduce shunt failure in uncontrolled series. The authors investigated the efficacy of this procedure in a prospective multicenter randomized trial. Methods. Children younger than 18 years old who were scheduled for t...Ventriculoperitoneal shunt; Shunt insertion; Shunt failure2003
223 Schmidt, Meic H.Role of photodynamic therapy in posterior fossa brain tumors: a preclinical study in a canine glioma modelPhotodynamic therapy was studied in dogs with and without posterior fossa glioblastomas. This mode of therapy consisted of intravenous administration of Photofrin-II at doses ranging from 0.75 to 4 mg/kg 24 hours prior to laser light irradiation in the posterior fossa. Tissue levels of Photofrin-l...Brain neoplasm; Posterior fossa; Photodynamic therapy; Glioblastomas; Dog; Photofrin-II; Canine glioma model1993
224 Dailey, Andrew T.; Brodke, Darrel S.Differences between neurosurgeons and orthopaedic surgeons in classifying cervical dislocation injuries and making assessment and treatment decisions: a multicenter reliability studyVariability exists in the management of cervical spinal injuries. The goal of this study was to assess the effect of training specialty (orthopedic surgery vs neurosurgery) on management of cervical dislocations.Cervical dislocation injuries; Classification; Orthopedic surgeons; Orthopaedic surgeons; Assessment decisions; Treatment decisions2008
225 Couldwell, William T.; Gottfried, Oren N.Too many? Too few. New study reveals current trends in U. S. neurosurgical workforceRemarkable changes in the neurosurgical specialty have taken place in the past 15 years. While advances in basic science have occurred and new technologies and therapies have proliferated, other, less propitious factors-such as the promises (some might say false promises) and hopes of managed care-h...2003-01-01
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