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Creator | Title | Description | Subject | Date |
| 176 |
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Olivera, Baldomero M. | Nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin ImI | We report the isolation, characterization, and total synthesis of a small peptide ligand for nicotinic acetylcholine receptors (nAChRs). It is highly active against the neuromuscular receptor in frog but noitn mice. In contrast, it induces seizures when injected centrally in mice and rats, suggesti... | Conotoxins; a-conotoxin ImI | 1994 |
| 177 |
 |
Olivera, Baldomero M. | Conodipine-M, a novel phospholipase A2 isolated from the venom of the marine snail Conus magus | We describe the purification and first biochemical characterization of an enzymatic activity in venom from the marine snail Conus magus. This enzyme, named conodipine-M, is a novel phospholipase A2 with a molecular mass of 13.6 ĸDa and is comprised of two polypeptide chains linked by one or more di... | Conotoxins; Conodipine-M; Conus magus | 1994 |
| 178 |
 |
Seger, Jon | Sexual dimorphism in the Hymenoptera | Spectacular sex differences of many kinds occur abundantly among the wasps, bees and ants that make up the insect order Hymenoptera. In some cases these differences are so extreme that males and females of the same species have been classified in different genera for decades, until a chance observa... | Reproductive; Insect; Morphology | 1994 |
| 179 |
 |
Gesteland, Raymond F.; Weiss, Robert B. | Efficient shine- Dalgarno sequence but not translation is necessary for LacZ mRNA stability in Escherichia coli | The 5' ends of many bacterial transcripts are important in determining mRNA stability. A series of Shine-Dalgarno (SD) sequence changes showed that the complementarity of the SD sequence to the anti-SD sequence of 16S rRNA correlates with lacZ mRNA stability in Escherichia coli. Several initiation c... | Protein Biosynthesis; Ribosomes; Escherichia coli; Shine-Dalgarno Sequence | 1994 |
| 180 |
 |
Gesteland, Raymond F.; Ives, Jeffrey T.; Stockham, Thomas G. | Automated film reader for DNA sequencing based on homomorphic deconvolution | An automated reader for electrophoresis based DNA sequencing methods is described that provides fast and accurate sequence determination. Digitized sequencing lanes are processed with homomorphic blind deconvolution in preparation for peak detection, interlane alignment, peak refinement and base cal... | Sequence Analysis; Electrophoresis; Automated Film Reader; Homomorphic Deconvolution | 1994 |
| 181 |
 |
Adler, Frederick R. | Construction of multidimensional clustered patterns | Ecological processes often depend upon the patterning, as well as the absolute density, of resources. In this paper, we develop methods for describing pattern from the perspective of the organism encountering and exploiting the resources, and for reconstructing pattern from the description. | Algorithms; clustered resources; foraging | 1994 |
| 182 |
 |
Bohs, Lynn A. | New species of Solanum section Cyphomandropsis (Solanaceae) from Bolivia | A new species of Solanum sect. Cyphomandropsis (Solanaceae), S. hibernum, is described from the western part of Dept. Santa Cruz, Bolivia. Its strongly discolorous leaves densely covered below with white dendritic hairs distinguish it from the other species in the section. | Solanum hibernum; Cyphomandropsis | 1994 |
| 183 |
 |
Gesteland, Raymond F.; Atkins, John F.; Tuohy, Therese M. | Uninterrupted translation through putative 12-nucleotide coding gap in sequence of carA: business as usual | Previous work of others reported an untranslated stretch of 12 nucleotides in the 5' coding sequence of carA from Pseudomonas aeruginosa. However, N-terminal protein sequencing of carA-lacZ translational fusions shows that these 12 nucleotides are normally translated in a continuous triplet manner, ... | Base Sequence; Protein Biosynthesis; Sequence Deletion | 1994 |
| 184 |
 |
Bohs, Lynn A. | Cyphomandra (Solanaceae) | Unusual ecological aspects of Cyphomandra include its pollination syndrome and herbivore relationships. Male euglossine bees may be important pollinators of Cyphomandra flowers, and the primary attractants may not be pollen, but odor substances secreted by the anther connectives. Specialized herbi... | Cyphomandra; Latin America | 1994 |
| 185 |
 |
Adler, Frederick R. | General test for interaction modification | How can measurements of population dynamics be used to deduce the mechanisms of interaction in an assemblage of species? We present a technique to use such measurements to distinguish among assemblages of species with no direct interactions, sets of species influenced predominantly by pairwise inter... | Species; Population; Dynamics | 1994 |
| 186 |
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Gesteland, Raymond F.; Atkins, John F.; Wills, Norma M. | rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshift | Base pairing between the 3' end of 16S rRNA and mRNA is shown to be important for the programmed -1 frameshifting utilized in decoding the Escherichia coli dnaX gene. This pairing is the same as the Shine-Dalgarno pairing used by prokaryotic ribosomes in selection of translation initiators, but for ... | Frameshifting; Escherichia coli; Binding Sites; Base Composition | 1994 |
| 187 |
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Adler, Frederick R. | Defended fortresses or moving targets? Another model of inducible defenses inspired by military metaphors | We use a common framework to compare three models of plant strategies to confront herbivory: constitutive defense, optimal inducible defense, and the "moving target." Plants with constitutive defenses retain a fixed defensive phenotype. Plants with optimal inducible defenses respond to attack by inc... | Constitutive defense; optimal inducible defense; phenotype | 1994 |
| 188 |
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Beckerle, Mary C.; Davis, Darrell R.; Winge, Dennis R. | Mutational analysis of the metal sites in an LIM domain | Site-directed mutagenesis was carried out map the residues that form the two Zn(I1) sites within a LIM domain. The C-terminal LIM domain derived from the cysteine-rich protein was utilized for this analysis and is referred to as LIMB. | LIM domains; Metal-binding | 1994 |
| 189 |
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Beckerle, Mary C. | Biochemical and molecular characterization of the chicken cysteine-rich protein, a developmentally regulated LIM-domain protein that is associated with the actin cytoskeleton | LIM domains are present in a number of proteins including transcription factors, a protooncogene product, and the adhesion plaque protein zyxin. The LIM domain exhibits a characteristic arrangement of cysteine and histidine residues and represents a novel zinc binding sequence (Michelsen et al., ... | Zyxin; Cysteine-rich proteins; cCRP; Actin; LIM domains | 1994 |
| 190 |
 |
| Local television news clips for June 14, 1994 featuring Mario Capecchi | This is a compilation of news clips from Salt Lake City's four major commercial television stations (Channels 2, 4, 5, and 13) lasting a total of 2 minutes, 59 seconds. The topic is Capecchi's winning of the General Motors Corporation's Alfred P. Sloan Jr. Prize for Outstanding Basic Science Contrib... | Transgenic mice; Gene targeting; Cancer - Research - Awards; Capecchi, Mario R.; Science - Awards - United States; Television broadcasting of news | 1994-06-14 |
| 191 |
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Capecchi, Mario R. | Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions. | The Hox genes encode transcription factors which mediate the formation of the mammalian body plan along the anteroposterior and appendicular axes. Paralogous Hox genes within the separate linkage groups are closely related with respect to DNA sequence and expression, suggesting that they could have ... | Animals; Atlas; Homozygote; Mice; Models, Genetic | 1994-07-28 |
| 192 |
 |
Capecchi, Mario R. | Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus. | Implantation within the mammalian uterus elicits dramatic changes in the growth, differentiation, and morphogenesis of the conceptus. This process is interrupted in mice carrying a targeted disruption of the murine evx1 gene, a homolog of the Drosophila even-skipped (eve) gene. Upon implantation, pr... | Extraembryonic; Homozygotes; Drosophila | 1994-08-15 |
| 193 |
 |
Clayton, Dale H. | New genus and three new species of chewing lice (Phthiraptera: Philopteridae) from Peruvian ovenbirds (Passeriformes: Furnariidae) | The new genus Furnariphilus is described to include three new species from Peruvian hosts within the passerine family Furnariidae, subfamily Furnariinae: F. pagei, the type species of the genus, from Furnarius leucopus Swainson; F. griffithsi from Sclerurus mexicanus Sclater; and F. parkeri from Scl... | Chewing lice; Peruvian ovenbirds; Phthiraptera; Furnariphilus; Ectoparasites; Peru; Furnarius leucopus; Sclerurus mexicanus; Sclerurus caudacutus | 1995 |
| 194 |
 |
Coley, Phyllis D. | What's up? Perspectives from the first international forest canopy conference at Sarasota, Florida, 1994 | Jumars, caribineers, pole pruners, tree bicycles, Bosun's chairs, booms, peconhas . . . these terms are not listed in most biological dictionaries. Nor are construction cranes or large treehouses or hot-air dirigibles listed as priority equipment for any scientific laboratories. But these are th... | | 1995 |
| 195 |
 |
Capecchi, Mario R. | Personal view of gene targeting | Gene targeting provides the means for creating strains of mice with mutations in virtually any gene.1 First, the desired mutation is introduced into a cloned copy of the chosen gene by standard recombinant DNA technology. The mutation is then transferred to the genome of a pluripotent mouse embryo-d... | | 1995 |
| 196 |
 |
Coley, Phyllis D. | Benefits and costs of defense in a neotropical shrub | Benefits and costs are central to optimality theories of plant defense. Benefit is the gain in fitness to reducing herbivory and cost is the loss in fitness to committing resources to defense. We evaluate the benefits and costs of defense in a neotropical shrub, Psychotria horizontalis. Plants were ... | Cost of defense; Growth-defense trade-off; Exclosures; Field experiment; Herbivory; Panama; Psychotria horizontalis; Rubiaceae; Tannins; Toughness; Tropics | 1995 |
| 197 |
 |
Olivera, Baldomero M.; McIntosh, J. Michael; Gray, William Robert; Hillyard, David R. | New family of conotoxins that block voltage-gated sodium channels | Conus peptides, including ω-conotoxins and α-conotoxins (targeting calcium channels and nicotinic acetylcholine receptors, respectively) have been useful ligands in neuroscience. In this report, we describe a new family of sodium channel ligands, the μO-conotoxins. | Conotoxins; Sodium channel blockers | 1995 |
| 198 |
 |
Seger, Jon; Davidson, Diane W. | Biological richness of deserts | A desert is "waterless," "treeless," "barren," "remote," "uninteresting," and "presumably uninhabited," according to the authoritative Oxford English Dictionary. The word is derived from deserere, a Latin verb meaning "to leave." In English, to desert is still to "abandon," "forsake," or "fail." Bec... | Desert life; Desert biodiversity | 1995 |
| 199 |
 |
Ehleringer, James R. | Carbon isotope discrimination in the C4 shrub Atriplex confertifolia along a salinity gradient | Carbon isotope discrimination (∆) was measured for leaves of Atriplex confertifolia along a salinity gradi~ ent in northern Utah. Over this gradient, the variation of ∆ values was high for a C4 species, and the ∆ values were positively correlated with salinity in both years of the study. Of th... | Carbon isotope ratio; Salt stress; Bundle sheath leakiness; Halophyte; Atriplex confertifolia; Salinity gradient | 1995 |
| 200 |
 |
Dale, Colin | Kinetics of maturation of trypanosome infections in tsetse | Estimates of the time delay between the infective bloodmeal and maturation (incubation or maturation time) for 4 trypanosome stocks (2 Trypanozoon and 2 Trypanosoma congolense) show that maturation time in tsetse is not a parasite species-specific constant. The mean incubation time of a Trypanosoma ... | | 1995 |
