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Creator | Title | Description | Subject | Date |
126 |
 | Bernstein, Paul S. | Retinal tubulin binds macular carotenoids | PURPOSE: To investigate the biochemical mechanisms responsible for the specific uptake, concentration, and stabilization of the carotenoids lutein and zeaxanthin in the macula. METHODS: Soluble extracts of bovine retina mixed with radioactive carotenoids were purified by hydrophobic interaction, ion... | Chromatography, Gel; Electrophoresis; Xanthophylls | 1997 |
127 |
 | Olson, Randall J. | Early experiences with microphaco | Microphaco is the separation of irrigation from aspiration that allows removal of cataracts through sub-2mm incisions. While proven intraocular lenses (IOLs) are not available at this time to take advantage of the small wounds, these wounds are advantageous from a separating irrigation standpoint w... | Microphaco; Cataracts; Irrigation; Wounds | 2004 |
128 |
 | Durney, Carl H. | An experiment in using interactive computer graphics in teaching transient transmission-line theory | An interactive computer graphics routine was developed and used in teaching EE 553, Electromagnetic Fields, autumn quarter, 1969, in the Electrical Engineering Department of the University of Utah. The routine displayed the propagation of the voltage ave form produced by a step-function generator do... | | 1970 |
129 |
 | Olson, Randall J. | Comparison of thermal features associated with 2 phacoemulsification machines | PURPOSE: To determine the thermal characteristics of the Legacy Advantec and Sovereign WhiteStar phacoemulsification machines during different clinically relevant scenarios. SETTING: In vitro study. METHODS: In water, temperature was recorded continuously on the sleeve in an artificial chamber, and ... | Cataracts; Wound Burns; Thermal Characteristics | 2006-02 |
130 |
 | Zhang, Kang | Expression of wild type and mutant ELOVL4 in cell culture: subcellular localization and cell viability | PURPOSE: ELOVL4 is a member of the fatty acid elongase (ELO) family of genes. Mutations of this gene are responsible for autosomal dominant Stargardt-like macular degeneration. However, the specific role of ELOVL4 in photoreceptor cells and the mechanism by which mutations in ELOVL4 causes macular d... | Endoplasmic Reticulum; Green Fluorescent Proteins; Microscopy, Fluorescence | 2004 |
131 |
 | Frederick, Jeanne M. | Centrin 2 is required for mouse olfactory ciliary trafficking and development of ependymal cilia planar polarity | Centrins are ancient calmodulin-related Ca2-binding proteins associated with basal bodies. In lower eukaryotes, Centrin2 (CETN2) is required for basal body replication and positioning, although its function in mammals is undefined. We generated a germline CETN2 knock-out (KO) mouse presenting with s... | | 2014-01-01 |
132 |
 | Olson, Randall J. | Efficacy and wound-temperature gradient of WhiteStar technology phacoemulsification through a 1.2 mm incision | PURPOSE: To evaluate the efficacy and wound-temperature gradients of WhiteStar micropulse technology using bimanual phacoemulsification without an irrigation sleeve through a 1.2 mm incision. SETTING: Island Eye Surgicenter, Carle Place, New York, USA. METHODS: Ten patients had bimanual phacoemulsif... | Endothelium, Corneal; Surgical Procedures; Lens Implantation; Wound Temperature gradient | 2003-06 |
133 |
 | Frederick, Jeanne M. | Inhibitors of metalloendoprotease activity prevent K+-stimulated neurotransmitter release from the retina of Xenopus laevis. | Metalloendoprotease activity was identified in retinal homogenates using a synthetic fluorogenic metalloendoprotease substrate and specific metalloendoprotease inhibitors. The requirement of metalloendoprotease activity in neurotransmitter release was examined during the depolarization-induced relea... | Neuromuscular Junction; Neurotransmitter Agents; Membrane Fusion | 1984 |
134 |
 | Normann, Richard A.; Maynard, Edwin M. | Neural interface for a cortical vision prosthesis | The development of a cortically based vision prosthesis has been hampered by a lack of basic experiments on phosphene psychophysics. This basic research has been hampered by the lack of a means to safely stimulate large numbers of cortical neurons. Recently, a number of laboratories have developed a... | Neuroprosthetics; Artificial Vision; Electrode Arrays; Multielectrode Recordings; Biocompatibility | 1999 |
135 |
 | Olson, Randall J.; Crandall, Alan S.; Caldwell, Karin D.; Jensen, Michael K. | Intraoperative crystallization on the intraocular lens surface | PURPOSE: To report a physician survey, laboratory studies, and clinical observations of intraoperative crystallization on the surface of the intraocular lens (IOL). METHOD: We sent a survey to all ophthalmologists in the states of Wyoming, Idaho, Montana, Utah, and Colorado asking whether crystalliz... | Cataract Extraction; Intraoperative Complications; Risk Factors | 1998-08 |
136 |
 | Normann, Richard A.; Kolb, Helga | Neural organization of the retina of the turtle Mauremys caspica: a light microscope and Golgi study | The organization of the retina of the turtle species Mauremys caspica, found in fresh water ponds of Israel, has been examined by light microscopical techniques including examination of fresh wholemount retina, one micron blue-stained vertical sections and Golgi-stained material. The anatomical find... | Turtle Retina; Photoreceptors; Golgi Technique; Amarcine Cells | 1988 |
137 |
 | Olson, Randall J. | Cohort study of 27 cases of endophthalmitis at a single institution | PURPOSE: To identify potential risk factors associated with post-cataract surgery bacterial endophthalmitis. SETTING: The John A. Moran Eye Center, Salt Lake City, Utah, USA. METHODS: This retrospective cohort study consisted of patients who had surgery for cataract(s) at this eye hospital. A 10% sa... | Cataract Extraction; Endophthalmitis; Wound Healing; Risk Factors | 2005-04 |
138 |
 | Angelucci, Alessandra | Layer-specific programs of development in neocortical projection neurons | How are long-range axonal projections from the cerebral cortex orchestrated during development? By using both passively and actively transported axonal tracers in fetal and postnatal ferrets, we have analyzed the development of projections from the cortex to a number of thalamic nuclei. We report th... | Axonal Transport; Efferent Pathways; Brain Mapping | 1995 |
139 |
 | Zhang, Kang | Novel mutation in the ELOVL4 gene causes autosomal dominant Stargardt-like macular dystrophy | PURPOSE. To conduct clinical and genetic studies in a European family with autosomal dominant Stargardt-like macular dystrophy (adSTGD-like MD) and to investigate the functional consequences of a novel ELOVL4 mutation | Macular dystrophy; ELOVL4 mutation; Genetics | 2004 |
140 |
 | Fuhrmann, Sabine; Zhang, Jianmin; Vetter, Monica L. | Investigation of Frizzled-5 during embryonic neural development in mouse | Cellular and tissue--tissue interactions regulate development of the central nervous system (CNS) and a paramount question is what is the nature of the signals involved in these interactions. The vertebrate eye represents an excellent and challenging CNS model because it contains multiple cell and ... | Mouse; Eye; Optic cup; Morphogenesis; Retina; Lens; Wnt; Frizzled; Pituitary | 2008 |
141 |
 | Kriesel, John D.; Maulden, Sarah Annamarie; Spruance, Spotswood L. | Anti-interleukin-6 antibodies inhibit herpes simplex virus reactivation. | Herpes simplex viruses (HSVs) infect epithelial cells, become localized in neurons, and can reactivate in response to a variety of stimuli, including ultraviolet light and hyperthermia. The sequence of gene activation during viral replication is known, but the molecular linkage between exogenous sti... | Mice, Inbred BALB C; Tumor Necrosis Factor-alpha; Virus Activation | 1997 |
142 |
 | Frederick, Jeanne M.; Thulin, Craig; Bernstein, Paul S. | Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye | Uptake, metabolism, and stabilization of xanthophyll carotenoids in the retina are thought to be mediated by specific xanthophyll-binding proteins (XBPs). A membrane-associated XBP was purified from human macula using ion-exchange chromatography followed by gel-exclusion chromatography. Two-dimensio... | Circular Dichroism; Isoelectric Focusing; Macula Lutea; Xanthophylls | 2004 |
143 |
 | Baehr, Wolfgang | Phenolic components from the leaves of the Ginkgo tree (Ginkgo biloba L) | No summary- Article is in German. | Flavonoids; Chromatography; Phenols; Plant Extracts; Ginkgo Biloba L. | 1968-05 |
144 |
 | Normann, Richard A.; Maynard, Edwin M. | Neuronal interactions improve cortical population coding of movement direction | Interactions among groups of neurons in primary motor cortex (MI) may convey information about motor behavior. We investigated the information carried by interactions in MI of macaque monkeys using a novel multielectrode array to record simultaneously from 12-16 neurons during an arm-reaching task. ... | Motor Cortex; Monkey; Population Coding; Movement | 1999 |
145 |
 | Normann, Richard A. | Effects of background illumination on the photoresponses of red and green cones | 1. The photoresponses of light- and dark-adapted red and green cone photoreceptors were recorded intracellularly in the retina of the turtle, Pseduemys scripta elegans. Background illumination produced similar effects on both types of cones. 2. In response to the onset of a prolonged, steady backgro... | Turtles; Adaptation, Ocular; Retina; Signal Transmission | 1979 |
146 |
 | Kriesel, John D.; Baringer, J R; Spruance, Spotswood L. | Correlation between detection of herpes simplex virus in oral secretions by PCR and susceptibility to experimental UV radiation-induced herpes labialis. | We examined the oral secretions of 25 patients for herpes simplex virus (HSV) at the time of and following experimental UV radiation (UVR). HSV was detected in one or more oral secretion specimens in 5 of 12 (42%) cases by cell culture and in 8 of 12 (67%) cases by PCR. On the day of UVR, HSV was de... | Polymerase Chain Reaction; Ultraviolet Rays; Simplexvirus | 1994 |
147 |
 | Baehr, Wolfgang | Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye | Visual sensation in vertebrates is triggered when light strikes retinal photoreceptor cells causing photoisomerization of the rhodopsin chromophore 11-cis-retinal to all-trans-retinal. The regeneration of preillumination conditions of the photoreceptor cells requires formation of 11-cis-retinal in t... | Microscopy, Fluorescence; Visual Perception; Membrane Proteins | 2004 |
148 |
 | Baehr, Wolfgang | Evaluation of the 17 kda prenyl binding protein as a regulatory protein for phototransduction in retinal photoreceptors | The mammalian rod photoreceptor phosphodiesterase (PDE6) holoenzyme is isolated in both a membrane-associated and a soluble form. Membrane binding is a consequence of prenylation of PDE6 catalytic subunits, whereas soluble PDE6 is purified with a 17-kDa prenyl-binding protein (PDEdelta) tightly boun... | Amino Acid Sequence; Immunohistochemistry; Phosphoric Diester Hydrolases | 2005 |
149 |
 | Baehr, Wolfgang | Novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD) | PURPOSE: To elucidate the phenotypic and biochemical characteristics of a novel mutation associated with autosomal dominant cone-rod dystrophy (adCORD). METHODS: Twenty-three family members of a CORD pedigree underwent clinical examinations, including visual acuity tests, standardized full-field ERG... | Polymorphism, Single-Stranded Conformational; Guanylate Cyclase-Activating Proteins; DNA Mutational Analysis | 2005 |
150 |
 | Larson, Scott A. | Strabismus surgery complications: prevention and management | Strabismus surgery is increasingly becoming a subspecialty domain, especially with cyclovertical muscles, restricted muscles, or reoperations. While is impossible to completely eliminate complications from strabimus surgery, it is possible to minimize their occurrence and significance by proper prev... | Malignant hyperthermia; Overcorrection; Strabismus; Surgery; Undercorrection | 2003 |