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126 Couldwell, William T.Penetrating craniocerebral injury resultant from gunshot wounds: gang-related injury in children and adolescentsWE PROSPECTIVELY AND retrospectively reviewed a series of 780 patients who presented to the University of Southern California/Los Angeles County Medical Center with a diagnosis of gunshot wound to the brain during an 8-year period. Of these, 105 were children ranging in age from 6 months to 17 yea...Craniocerebral injury; Los Angeles County General Hospital; University of Southern California School of Medicine1993
127 Osborne, Anne G.; Couldwell, William T.Rathke cleft cyst intracystic nodule: a characteristic magnetic resonance imaging finding.OBJECT: The fluid content of Rathke cleft cysts (RCCs) displays variable appearances on magnetic resonance (MR) images and can appear indistinguishable from other intrasellar or suprasellar cystic lesions. Intracystic nodules associated with individual RCCs have been noted, but to date their signifi...Brain Neoplasms; Central Nervous System Cysts; Magnetic Resonance Imaging2005-11-01
128 Couldwell, William T.; Apfelbaum, Ronald I.Decompression of cavernous sinus meningioma for preservation and improvement of cranial nerve functionMeningiomas are the most common tumors affecting the cavernous sinus (CS). Despite advances in microsurgery and radiosurgery, treatment of CS meningiomas remains difficult and controversial. As in cases of other meningiomas, the goal of treatment for CS meningioma is long-term growth control and pre...2006-07
129 Schmidt, Meic H.Diffuse large B-cell lymphoma presenting as a sacral tumorPrimary lymphomas of the sacrum are rare tumors, reported only in a few cases in the literature. The authors describe two patients with diffuse large B-cell lymphomas presenting as a sacral tumor. In the first case a 52-year-old man presented with progressive back pain, bilateral radicular pain, an...B-cell lymphoma; Sacral tumor2003
130 Digre, Kathleen B.Serum vitamin A concentration is elevated in idiopathic intracranial hypertension.OBJECTIVE: The primary purpose was to investigate whether serum vitamin A concentration is associated with idiopathic intracranial hypertension (IIH). The secondary aim was to obtain pilot data regarding the amount of vitamin A ingested by patients and controls. BACKGROUND: Vitamin A is an attractiv...Vitamin A; Retinol; Idiopathic intracranial hypertension; Chromatography2007-02-01
131 Couldwell, William T.; Harnsberger, H. RicOronasopharyngeal chordomasBackground: Chordomas are rare tumors derived from notochordal remnants. The authors report on a series of three cases of primary familial oronasopharyngeal chordomas treated at our institution. Methods: A retrospective chart review was completed of the three cases of primary familial oronasopharyng...Oronasopharyngeal; Chordoma; Pharynx; Notochord; Transoral; Skull base2009
132 Couldwell, William T.Combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumorsCOMPLEX TUMORS OF the glomus jugulare present a surgical challenge because of their difficult location, extreme vascularity, and involvement with multiple cranial nerves. Modern microneurosurgical and cranial base techniques have enabled safe total removal of these complicated tumors. We describe a ...Cranial base approach; Surgical approach; Glomus jugulare tumor; Jugular foramen exposure; Microsurgical anatomy2006
133 Schmidt, Meic H.Castleman disease of the spine mimicking a nerve sheath tumorCastleman disease is a rare lymphoproliferative disease of unknown cause. In most cases, afflicted patients present with a mediastinal mass although the disease may manifest in numerous other sites, including intracranially and rarely intraspinally. The authors report on the case of a 19-year-old wo...Castleman disease; Nerve sheath tumor2007
134 Schmidt, Meic H.Light-emitting diodes as a light source for intraoperative photodynamic therapyTHE DEVELOPMENT OF more cost-effective light sources for photodynamic therapy of brain tumors would be of benefit for both research and clinical applications. In this study, the use of light-emitting diode arrays for photodynamic therapy of brain tumors with Pholofrin porfimer sodium was investiga...Photodynamic therapy; Brain tumors; Brain tumor therapy; Photofrin; LED1996
135 Kestle, John R. W.Tracking resident work hours: available software is not yet ideal, but it's helpfulAn ideal system would be completely passive and would allow more detailed tracking of activity inside the hospital. A new reality began July 1. We are all now responsible for tracking our residents' work hours and ensuring compliance with the new regulations mandated by the Accreditation Council fo...Resident work hours; Tracking; TimeClock system2003
136 Couldwell, William T.Posterior fossa brain tumors and arterial hypertensionHypertension caused by arterial compression of the rostral ventrolateral medulla is well described. Much less information is available on the association between neurogenic hypertension and posterior fossa brain tumors. To date, multiple reports have supported the impression that a small subpopulat...Posterior fossa tumors; Brain stem; Arterial hypertension; Essential hypertension; EHTN2006
137 Kestle, John R. W.Propionibacterium encephalitis [Letter to the editor]To THE EDITOR: We read with interest the article by Camarata, et al., reporting two cases of dorsal midbrain encephalitis (Camarata PJ, McGeachie RE, Haines S J: Dorsal midbrain encephalitis caused by Propionibacterium aches. Report of two cases. J Neurosurg 72." 654-659, April, 1990). There are...1990
138 Schmidt, Meic H.Spinal meningiomas: surgical management and outcomeAdvances in imaging and surgical technique have improved the treatment of spinal meningiomas; these include magnetic resonance imaging, intraoperative ultrasonography, neuromonitoring, the operative microscope, and ultrasonic cavitation aspirators. This study is a retrospective review of all patient...Spinal meningioma; Spinal tumor; Intradural; Extramedullary2003
139 Couldwell, William T.Neurosurgical workforce trends in the United StatesObject. The purpose of this study was to evaluate the US neurosurgery workforce by reviewing journal recruitment advertisements published during the past 10 years. Methods. The number of available academic and private neurosurgical staff positions was determined based on recruitment advertisements ...2005-02
140 Swallow, Charles E.; Tsuruda, Jay S.; Digre, Kathleen B.; Glaser, Matthew J.; Davidson, H. Christian; Harnsberger, H. RicTerson syndrome: CT evaluation in 12 patients.PURPOSE: Terson syndrome may be overlooked in the acute setting and often requires ophthalmologic intervention to prevent long-term visual loss. In this syndrome, vitreous or retinal hemorrhage results from an abrupt rise in intracranial pressure, leading to retinal venous hypertension and intraocul...Retinal Hemorrhage; Visual Acuity; Vitreous Hemorrhage1998-04
141 Couldwell, William T.Thrombosed Basilar Apex Aneurysm presenting as a third ventricular mass and hydrocephalus: case report and review of the literatureAneurysms presenting as third ventricular masses are uncommon; most are giant aneurysms arising from the basilar apex. We present a case of a thrombosed basilar apex aneurysm presenting as a third ventricular mass and hydrocephalus in a 55-year-old man. The case is unique in the literature as the an...Basilar Apex Aneurysm; Ventricular Mass; Third Ventriculostomy2005-04
142 Couldwell, William T.Review by Oren N. Gottfried, M.D. and William T. Couldwell, M.D., Ph.D for Neurosurgery Journal Club. (Yadav JS, Wholey MH, Kuntz RE, et al: Protected carotid-artery stenting versus endarterectomy in high-risk patients.)This is an important study that helps further define a role for carotid stenting as a therapeutic option for atherosclerotic carotid disease. There is a need for a larger-scale multi-centered trial with increased numbers patients and longer follow-up to identify appropriate patients for either endar...Carotid Stenosis; Endarterectomy, Carotid; Stents2005-01-07
143 Jaeckle, Kurt A.; Digre, Kathleen B.; Jones, Christopher R.; Bailey, Peter L.Central neurogenic hyperventilation: pharmacologic intervention with morphine sulfate and correlative analysis of respiratory, sleep, and ocular motor dysfunction.Central neurogenic hyperventilation (CNH), for which there is no effective therapy, can eventually result in respiratory fatigue and death. This report describes a patient with CNH due to a brainstem anaplastic astrocytoma who also exhibited disturbances of sleep and ocular motor function. The CNH r...Central Neurogenic H yperventilation; Ocular Motor Dysfunction1990-11
144 Kestle, John R. W.Effect of hyperventilation on regional cerebral blood flow in head-injured childrenObjectives: To study cerebral blood flow and cerebral oxygen consumption in severe head-injured children and also to assess the effect of hyperventilation on regional cerebral blood flow. Design: Prospective cohort study. Setting: Pediatric intensive care unit at a tertiary-level university childre...Cerebral blood flow; Head injury; Jugular venous oximetry; Xenon computed tomography scan; Head-injured children1997
145 Schmidt, Meic H.Role of thoracoscopic spinal surgery in the management of pyogenic vertebral osteomyelitisStudy Design. Case report, operative technique. Objectives. Vertebral osteomyelitis is frequently associated with elderly and debilitated patients who have significant medical comorbidities. If surgical debridement is contemplated, an open anterior approach like a thoracotomy can be associated with...Thoracoscopic spinal surgery; Pyogenic vertebral osteomyelitis2004
146 Couldwell, William T.Management of pituitary adenomasWe present an overview of the management of pituitary adenomas, with discussions of microanatomy, of diagnostic studies of general neuroendocrine function, and of radiologic evaluation. We discuss the diagnosis of pituitary adenoma and its treatment with sections on null cell, prolactin (PRL)-secre...Pituitary adenoma; Transsphenoidal surgery; Corticotropin; Prolactin; Growth hormone; Transcranial surgery1994
147 Dailey, Andrew T.Emergent aneurysm clipping without angiography in the moribund patient with intracerebral hemorrhage: the use of infusion computed tomography scansTHE AUTHORS REPORT their experience with 25 patients (mean age, 44.3 ± 12.1 years) with an intracerebral hematoma (ICH) from a ruptured aneurysm who were emergently operated on without angiography. Instead, preoperative high-resolution infusion computed tomography (CT) scans were used to identify...Ruptured aneurysms; Computed tomography; Infusion computed tomography; Aneurysm clipping1993
148 Couldwell, William T.Glioma invasionA characteristic pathological feature of malignant glioma cells is their ability to extensively invade surrounding brain parenchyma-particularly along white matter tracts- thus rendering focal therapies incapable of controlling tumor growth and resulting in inevitable recurrence. In this regard, ...2001
149 Dailey, Andrew T.Sciatic nerve sarcoidosis: utility of magnetic resonance peripheral nerve imaging and treatment with radiation therapySarcoidosis may involve both the central and peripheral nervous system, although peripheral nerve manifestations are usually seen late in the disease. In this report, the authors describe a case of sarcoidosis in a 22-year-old woman who presented with a foot drop. Although results of conventional lu...Peripheral nerve imaging; Radiation therapy2004
150 Couldwell, William T.Surgical outcomes in 118 patients with Rathke cleft cystsObject. Microscopic Rathke cleft cysts are a common incidental autopsy finding, but some Rathke cleft cysts can become sufficiently large to cause visual impairment, hypothalamic-pituitary dysfunction, and headaches. In this study patients were evaluated pre- and postoperatively to ascertain the cli...2005-02
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