101 - 125 of 4,589
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TitleDescriptionSubjectCollection
101 Lymphoblast in splenic white pulp (rat, human)Electron microscopy (A, rat) and Methyl green (B, human). Upon antigenic stimulation the lymphocytes in the germinal centre proliferate and generate activated B cells or lymphoblasts which seed towards marginal zone and red pulp while differentiating. Due to the increased number of lymphoblasts, ret...electron microscopy; lymphoblastPoja Histology Collection - Lymphatic Tissues and Organs Subset
102 Phagocytosis in small splenic blood vessel (mouse)Electron microscopy. Stain: Peroxidase reaction with diaminobenzidin staining. A diversity of red blood cells is black-stained due to the staining of hemoglobin by oxidized benzidin. Circulating lymphocytes (2) in the lumen (*) remain unstained. An oblong monocyte (1) developing into a macrophage h...electron microscopy; phagocytosisPoja Histology Collection - Lymphatic Tissues and Organs Subset
103 Survey of spleen (human)Stain: Azan. The spleen is covered by a capsule (1) of dense connective tissue and elastic fibers. The capsule continues into the spleen as trabeculae (2) carrying blood vessels and nerve fibers. As arteries leave the trabeculae it becomes invested by a sheath of T cells forming a PALS (3) or periar...white pulp; sinusoid; red pulp; PALSPoja Histology Collection - Lymphatic Tissues and Organs Subset
104 : Lymph node (human)Stain: Azan. Specialized venules (1) or so-called high endothelial venules (HEV) are here located in the paracortical area (4) close to the lymphatic follicle (2+3). The HEVs are lined by cuboidal or columnar endothelial cells that possess specific homing receptors for antigen-primed B- and T ly...paracortex; high endothelial venule (HEV); germinal centerPoja Histology Collection - Lymphatic Tissues and Organs Subset
105 Red pulp of spleen with perfused venous sinusoids (human)Stain: Azan. Cross-sectioned venous sinusoids with splenic cord (1). The wall of a sinusoid is composed of elongated rod-like endothelial cells that are orientated parallel to each other in the long axis of the sinusoid. There is a discontinuous pale-stained basement membrane (difficult to observe i...sinusoid ; red pulp; splenic cord; central arteriolePoja Histology Collection - Lymphatic Tissues and Organs Subset
106 Venous circulation pattern in perfused spleen (human)Stain: Azan. The composed picture shows part of the splenic circulation system at several enlargements (inset, A, B). The open venous sinusoids (1) drain via short pulp veins into thin-walled trabecular veins (2), subsequently into thick-walled trabecular veins (4). The trabeculae originate from the...splenic circulation; trabecular veins; sinusoid ; PALSPoja Histology Collection - Lymphatic Tissues and Organs Subset
107 Thymus medulla (rat, young adult)Electron microscopy. Epithelioreticular cells of the medulla (1) close to each other. The electron-light cytoplasm contains many small vesicles (1, Golgi area) as well as cross-sections of vacuoles (2) with small finger-like cytoplasmic extrusions in the lumen. Electron-dense lysosomal structures (3...medullar epithelioreticular cell ; thymus medulla; lymphoid tissuePoja Histology Collection - Lymphatic Tissues and Organs Subset
108 Thymus medulla (rat, young adult)Electron microscopy. Surrounded by thymocytes (3) a medullary macrophage with an electron-light nucleus (1). The cytoplasm contains many electron-dense lysosomes of varying sizes and forms (2).medullar macrophage; lymphoid tissuePoja Histology Collection - Lymphatic Tissues and Organs Subset
109 Scheme electron microscopy of the border of secondary nodule/red pulp in spleenThe left figure POJA-L974 shows a scheme of histological impression of a survey of a secondary splenic follicle or nodule. The rectangle is enlarged in the right figure POJA-L976B and shows the following elements: A. germinal centre; B. mantle zone; C. dendritic cell area; D. marginal zone; E. ...white pulp; marginal zone; red pulp; antigen presenting cell (APC)Poja Histology Collection - Lymphatic Tissues and Organs Subset
110 Thymus (human, newborn, low and higher magnification)Stain: Hematoxylin & eosin. The infantile thymus is surrounded by connective tissue capsule (3) from where vascularized interlobular septa (or trabeculae, 3) penetrate into the lobulated organ. Each lobule consists of a darker stained cortex (2) and a lighter stained medulla (1). The medulla has a l...Zhen; thymus cortex; thymus medulla; Hassall's corpuscle ; Lymphoid tissuePoja Histology Collection - Lymphatic Tissues and Organs Subset
111 The effect of cyclophosphamide on the CD8-thymocytes in thymus (rat)Stain: Immunoperoxidase staining with diaminobenzidin (DAB) and hematoxylin counterstained on frozen section. A single injection with cyclophosphamide (CP, 70 mg/ml) induces a transient cortical involution after 4 days, i.e. the darkly stained cortex and the lightly stained medulla in normal thymus ...cyclophosphamide; CD8 monoclonal antibody; immunosuppression; lymphoid tissuePoja Histology Collection - Lymphatic Tissues and Organs Subset
112 Detailed localization of heparan sulfate (HS) in spleen (rat)Stain: Immunofluorescence of Alexa 594 red labeled single chain antibody 3C3 for heparan sulfate (HS). The antibody stains HS epitopes of the meshwork of reticulum cells and the basal membrane of blood vessels. A: survey white pulp spleen. B: marginal sinuses between PALS area and red pulp. C: red...white pulp; PALS; heparan sulfatePoja Histology Collection - Lymphatic Tissues and Organs Subset
113 Immunohistochemistry with cellular markers in thymus (rat)Stain: Alexa-594 red immunofluorescence. (1) medulla. (2) cortex. (A-survey, B-cortex): ER13 antibody stains for MHC-class II antigens on reticular cell types in medulla and cortex. (C): ED1 monoclonal antibody stains a single chain glycoprotein of 110 kDa on the lysosomal membrane of myeloid cel...ER13 antibody; ED1 monoclonal antibody; ED2 monoclonal antibody; ER2 monoclonal antibodyPoja Histology Collection - Lymphatic Tissues and Organs Subset
114 Phagocytosis in splenic red pulp (mouse)Electron microscopy. Stain: Peroxidase reaction with diaminobenzidin staining. A diversity of red blood cells in the red pulp can be discerned due to the DAB staining of hemoglobin by oxidized benzidin (dark and light staining). The macrophage (1) shows peroxidase activity along the nuclear membran...electron microscopy; phagocytosisPoja Histology Collection - Lymphatic Tissues and Organs Subset
115 Red pulp of spleen with venous sinusoids (monkey, human)Stain: A: Silver stain (Movat) (monkey); B: Silver stain (Gomori) (human). (A): The darkly stained fibres are conspicuous in the PALS (1) area arranged in parallel rows. The blood vessels continue in the surrounding splenic sinusoids (4). The wall of the sinusoid is built as a grid, the space is su...sinusoid; reticular fibresPoja Histology Collection - Lymphatic Tissues and Organs Subset
116 Survey of pharyngeal tonsil ('lymphoepithelial tissues', 'gut-associated lymphatic tissue' or GALT) (human)Stain Azan. The solitary pharyngeal tonsil is localized in the pharyngeal fornix and belongs to the so-called Waldeyer's ring of pharyngeal lymphatic tissue. A survey shows the folded columnar epithelium (1) with faintly light-stained goblet cells with clefts (2) in between. The lamina propria co...pharyngeal tonsil; GALTPoja Histology Collection - Lymphatic Tissues and Organs Subset
117 Cystic corpuscle in thymus (human, adult)Stain: Azan. With age the remaining Hassall's corpuscles become more prominent and might represent large multiform structures of over hundreds of microns. The central cells (*) are keratinized. They might be swollen, calcify and become necrotic eventually, or undergo lysis, leaving a large cystic st...thymic corpuscle (Hassalls); epithelioreticular cell (ERC); lymphoid tissuePoja Histology Collection - Lymphatic Tissues and Organs Subset
118 Peroxidase reaction in reticular cell and myelocytes (postnatal liver, rat)Electron microscopy (peroxidase reaction with diaminobenzidin staining). The elongated reticular cell (1) shows peroxidase activity within the perinuclear space as well as the rough endoplasmic reticulum (species-dependent). It is surrounded by three eosinophilic myelocytes (2) with a positive react...Poja Histology Collection - Blood & Bone Marrow Subset
119 Plasma cell (liver, rat)Electron microscopy. The mature plasma cell or plasmacyte shows an eccentric nucleus with a characteristic chunky distribution of heterochromatin along the inner nuclear membrane (spoke-wheel effect in light microscopy). Juxtanuclearly an elaborate Golgi area (2) (cytocentrum/centrosome). The cytopl...Poja Histology Collection - Blood & Bone Marrow Subset
120 Three basophilic erythroblasts in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). Three basophilic erythroblasts (1) with intense blue stained cytoplasm, and some so called ears or cytoplasmic projections (arrows). Chromatin strands are thicker than in the proerythroblast. Generally no nucleoli are seen. (2) Damaged or smudged eosinophilic myelocy...Poja Histology Collection - Blood & Bone Marrow Subset
121 Polychromatic erythroblasts and neutrophilic granulocytes in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). Three polychromatic erythroblasts or normoblasts (1) and two neutrophils (2). The erythroblasts show light basophilic cytoplasm and well condensed nuclear chromatin. The lower neutrophil (more mature) has a more segmented nucleus than the upper one.Poja Histology Collection - Blood & Bone Marrow Subset
122 Erythron in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). The erythron or erythroblastic island consists of a large reticulum cell (1) surrounded by erythroblastic cell types (2) at varoius stages of differentiation. The nucleus of the reticulum cell (histiocyte) usually contains a noticeable nucleolus. At distance, some my...Poja Histology Collection - Blood & Bone Marrow Subset
123 Mast cell in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). The mast cell (1) is characterized by the presence of coarse purple-black granules and a nucleus with oval, central nucleus. The granules contain pharmacologically active mediators such as heparin, histamine, neutrophil- and eosinophil-chemotactic factors, vasoactive...Poja Histology Collection - Blood & Bone Marrow Subset
124 Degenerating granulocytes in peripheral blood smear (human)Stain: May-Grnwald-Giemsa (MGG).Two neutrophils with degenerated nuclei. Note the pyknotic pattern (like mature erythroblast) of the separated and rounded nuclear lobes and the granules in the cytoplasm. Normally only a small number of granulocytes die in the blood.Poja Histology Collection - Blood & Bone Marrow Subset
125 Giant plasma cell in peripheral blood smear (human)Stain: May-Grnwald-Giemsa (MGG). A giant plasma cell with diffusely spread immunoglobulins in the cytoplasm. The Golgi area remains unstained (white area).Poja Histology Collection - Blood & Bone Marrow Subset
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