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101 Dailey, Andrew T.Variations in surgical treatment of cervical facet dislocationsObjective. To explore surgeon preference in the choice of surgical approach in the treatment of traumatic cervical facet dislocations. Summary of Background Data. The choice of surgical approach in the treatment of traumatic cervical dislocations is highly variable and maybe influenced by a vari...Cervical facet dislocations; Spine Trauma Study Group2008
102 Schmidt, Meic H.Repeated operations for infiltrative low-grade gliomas without intervening therapyProgression of infiltrative low-grade gliomas (LGGs) has been reported previously. The limitations of such studies include diverse histological grading systems, intervening therapy, and the lack of histological confirmation of malignant tumor progression. The aim of this study was to determine tumo...Infiltrative low-grade gliomas; LGG; Tumor progression; Repeated operations; Tumor recurrence2003
103 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 2: assessment of functional outcomeStandards. It is recommended that functional outcome be measured in patients treated for low-back pain due to degenerative disease of the lumbar spine by using reliable, valid, and responsive scales. Examples of these scales in the low-back pain population include the following: The Spinal Stenosi...Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines; Treatment outcome; Functional outcome2005
104 Dailey, Andrew T.Modulation of macrophage and microglial responses to axonal injury in the peripheral and central nervous systemsOBJECTIVE: After axonal injury, macrophages rapidly infiltrate and become activated in the mammalian peripheral nervous system (PNS) but not the central nervous system (CNS). We used the dorsal root pathway to study factors that modulate the response of macrophages to degenerating axons in both the ...Axonal injury; Macrophage response; Microglial response; Peripheral nervous system; Lewis rats1999
105 Kestle, John R. W.; MacDonald, Joel D.; Schmidt, Richard H.Marked reduction of cerebral vasospasm with lumbar drainage of cerebrospinal fluid after subarachnoid hemorrhageObject. Cerebral vasospasm after subarachnoid hemorrhage (SAH) continues to be a major source of morbidity in patients despite significant clinical and basic science research. Efforts to prevent vasospasm by removing spasmogens from the subarachnoid space have produced mixed results. The authors hyp...Cerebral vasospasm; Lumbar drainage2004
106 Couldwell, William T.; Gillespie, David L.; Jensen, Randy L.Novel model of intracranial meningioma in mice using luciferase-expressing meningioma cellsObject. Meningioma research has been hindered by the inability to sequentially measure intracranial tumor growth in a cost-effective, efficient manner. Recently, the luciferase gene has been transfected into cancer lines to obtain cells that express the luciferase enzyme, which oxidizes luciferin in...2008-01-01
107 Couldwell, William T.Assessment of long-term remission of acromegaly following surgeryObject. The criteria for remission of acromegaly following transsphenoidal adenoma resection are in evolution. In the present study the authors evaluate the utility of predicting long-term remission by reference to a single fasting growth hormone (GH) level on the 1st postoperative day. Methods. A ...Acromegaly; Pituitary adenoma; Transsphenoidal surgery; Growth hormone; Insulin-like growth factor I2003-01-01
108 Dailey, Andrew T.; Brodke, Darrel S.Cervical end of an occipitocervical fusion: a biomechanical evaluation of 3 constructsObject. Stabilization with rigid screw/rod fixation is the treatment of choice for craniocervical disorders requiring operative stabilization. The authors compare the relative immediate stiffness for occipital plate fixation in concordance with transarticular screw fixation (TASF), C-1 lateral mass...Harms technique; Occipitocervical fusion; Transarticular screw; Translaminar screw; Craniocervical instability2008
109 Kestle, John R. W.; Brockmeyer, Douglas LeeOutcomes after decompressive craniectomy for severe traumatic brain injury in childrenObject. Severe traumatic brain injury (TBI) is often accompanied by early death due to transtentorial herniation. Decompressive craniectomy, performed alone or in conjunction with evacuation of the mass lesion, can reduce the incidence of raised intracranial pressure (ICP). In this paper the authors...Traumatic brain injury; Decompressive craniectomy; Pediatric neurosurgery2006
110 Digre, Kathleen B.; Couldwell, William T.; Amini, AminPhotophobia in a blind patient: An alternate visual pathway. Case report.Photophobia is a common neurological and ophthalmological symptom that has been associated with a growing number of neurosurgical conditions, especially compressive lesions. The exact signaling pathways and neurophysiological features of the disorder are not well understood; however, data from multi...Photophobia, Blindness, Signaling Pathway, Pretectal Nuclei, Trigeminal Pathway2006-12-14
111 Couldwell, William T.; Jensen, Randy L.; Gillespie, David L.Celecoxib inhibits meningioma tumor growth in a mouse xenograft modelBackground: Treatments for recurrent meningiomas are limited. We previously demonstrated universal expression of COX-2 in meningiomas and dose-dependent growth inhibition in vitro with celecoxib, a COX-2 inhibitor. We therefore tested the effects of celecoxib on meningioma growth in a mouse xenograf...Meningioma; Cyclooxygenase-2; COX-2; Celecoxib2007
112 Couldwell, William T.Management of cysticercosis cerebriInfestation of the central nervous system (CNS) with the parasitic larval form of the cestode Taenia solium, Cysticercosis Cerebri represents an endemic problem in much of the underdeveloped world. In such areas, up to 4% of the population maybe affected by neurocysticercosis, and it accounts for u...Taenia solium; Cysticercosis Cerebri; Parenchymal cyst; Basilar cisternal cyst; Intraventricular cyst1989
113 Couldwell, William T.Prolactinomas: focus on indications, outcomes and management of recurrencesAlthough prolactinomas are discovered at autopsy with equal frequency in women and men, they present clinically in women far more often than in men. In children, "in whom they are the most common type of adenoma, prolactinomas are seen more often in girls than in boys. In a series of nearly 400 PRL...Outcome; Pituitary adenoma; Prognosis; Prolactin; Transsphenoidal surgery1999
114 Schmidt, Meic H.Spinal epidural lipomatosis: a review of its causes and recommendations for treatmentSpinal epidural lipomatosis is most commonly observed in patients receiving long-term exogenous steroid therapy, but can also be seen in patients with endogenous steroid overproduction, obesity, or idiopathic disease. With this condition, there is hypertrophy of the epidural adipose tissue, causing ...Spinal epidural lipomatosis; Steroid; Hypertrophy; Adipose tissue2004
115 Couldwell, William T.Zones of approach for craniofacial resection: minimizing facial incisions for resection of anterior cranial base and paranasal sinus tumorsAnterior cranial base tumors are surgically resected with combined craniofacial approaches that frequently involve disfiguring facial incisions and facial osteotomies. The authors outline three operative zones of the anterior cranial base and paranasal sinuses in which tumors can be resected with th...Anatomic study; Anterior cranial base; Cranial base surgery; Craniofacial surgery; Minimally invasive2003
116 Kestle, John R. W.It's randomized and double blinded... what more do we want?This issue of Journal of Neurosurgery: Pediatrics presents a randomized trial in which investigators have evaluated antimicrobial suture (AMS) in the prevention of shunt infection. The authors randomized 84 shunt procedures in 61 patients over 21 months. The surgeons and patients were blinded to...2008
117 Couldwell, William T.Use of cylindrical titanium mesh and locking plates in anterior cervical fusionAfter performing anterior cervical corpectomy or discectomy for cervical spondolytic myelopathy or radiculopathy, iliac crest bone graft and fibular auto- or allograft is often used to achieve arthrodesis in the cervical spine. The purpose of this study was to evaluate the use of a cylindrical titan...Anterior cervical fusion; Arthrodesis; Cylindrical titanium mesh; Lordosis; Kyphosis2001
118 Couldwell, William T.Increasing exposure of the petrous internal carotid artery for revascularization using the transzygomatic extended middle fossa approach: a cadaveric morphometric studyWhen internal carotid artery (ICA) sacrifice is planned in the management of difficult tumors or aneurysms at the cranial base, the petrous ICA may be a useful site for anastomosis for interpositional vascular bypass. However, exposure of the artery and performing an anastomosis in this region may...Revascularization; Internal carotid artery; Cranial base tumors; Giant aneurysms; Interpositional bypass; Surgical approach; Middle fossa2006
119 Couldwell, William T.Penetrating craniocerebral injury resultant from gunshot wounds: gang-related injury in children and adolescentsWE PROSPECTIVELY AND retrospectively reviewed a series of 780 patients who presented to the University of Southern California/Los Angeles County Medical Center with a diagnosis of gunshot wound to the brain during an 8-year period. Of these, 105 were children ranging in age from 6 months to 17 yea...Craniocerebral injury; Los Angeles County General Hospital; University of Southern California School of Medicine1993
120 Osborne, Anne G.; Couldwell, William T.Rathke cleft cyst intracystic nodule: a characteristic magnetic resonance imaging finding.OBJECT: The fluid content of Rathke cleft cysts (RCCs) displays variable appearances on magnetic resonance (MR) images and can appear indistinguishable from other intrasellar or suprasellar cystic lesions. Intracystic nodules associated with individual RCCs have been noted, but to date their signifi...Brain Neoplasms; Central Nervous System Cysts; Magnetic Resonance Imaging2005-11-01
121 Couldwell, William T.; Apfelbaum, Ronald I.Decompression of cavernous sinus meningioma for preservation and improvement of cranial nerve functionMeningiomas are the most common tumors affecting the cavernous sinus (CS). Despite advances in microsurgery and radiosurgery, treatment of CS meningiomas remains difficult and controversial. As in cases of other meningiomas, the goal of treatment for CS meningioma is long-term growth control and pre...2006-07
122 Schmidt, Meic H.Diffuse large B-cell lymphoma presenting as a sacral tumorPrimary lymphomas of the sacrum are rare tumors, reported only in a few cases in the literature. The authors describe two patients with diffuse large B-cell lymphomas presenting as a sacral tumor. In the first case a 52-year-old man presented with progressive back pain, bilateral radicular pain, an...B-cell lymphoma; Sacral tumor2003
123 Digre, Kathleen B.Serum vitamin A concentration is elevated in idiopathic intracranial hypertension.OBJECTIVE: The primary purpose was to investigate whether serum vitamin A concentration is associated with idiopathic intracranial hypertension (IIH). The secondary aim was to obtain pilot data regarding the amount of vitamin A ingested by patients and controls. BACKGROUND: Vitamin A is an attractiv...Vitamin A; Retinol; Idiopathic intracranial hypertension; Chromatography2007-02-01
124 Couldwell, William T.; Harnsberger, H. RicOronasopharyngeal chordomasBackground: Chordomas are rare tumors derived from notochordal remnants. The authors report on a series of three cases of primary familial oronasopharyngeal chordomas treated at our institution. Methods: A retrospective chart review was completed of the three cases of primary familial oronasopharyng...Oronasopharyngeal; Chordoma; Pharynx; Notochord; Transoral; Skull base2009
125 Schmidt, Meic H.; Apfelbaum, Ronald I.Cervical spinal metastasis: anterior reconstruction and stabilization techniques after tumor resectionObject. In a review of the literature, the authors provide an overview of various techniques that have evolved for reconstruction and stabilization after resection for metastatic disease in the subaxial cervical spine. Methods. Reconstruction and stabilization of the cervical spine after vertebral...Cervical spine reconstruction; Metastasis; Spine tumor; Corpectomy; Stabilization technique; Vertebral body2003
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