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101 Couldwell, William T.Cholesteatoma of the clivus case reportObjective: Cholesteatomas (CNS epidermoids) can be found intradurally or extradurally in the central nervous system. Extradural intraosseous lesions are most commonly found in the petrous bone. Design: Case report Clinical Presentation: The authors describe a unique case of a clival cholesteatoma o...2006-01-01
102 Kestle, John R. W.Natural history of cerebral cavernous malformationsTo determine the natural history of brain cavernous malformations, the authors entered patients referred to their center into a prospective registry between 1987 and 1993. All patients underwent magnetic resonance imaging, which showed the typical appearance of this lesion, and conservative manageme...Cavernous malformation; Vascular malformation; Seizure1995
103 Couldwell, William T.Zones of approach for craniofacial resection: minimizing facial incisions for resection of anterior cranial base and paranasal sinus tumorsAnterior cranial base tumors are surgically resected with combined craniofacial approaches that frequently involve disfiguring facial incisions and facial osteotomies. The authors outline three operative zones of the anterior cranial base and paranasal sinuses in which tumors can be resected with th...Anatomic study; Anterior cranial base; Cranial base surgery; Craniofacial surgery; Minimally invasive2003
104 Schmidt, Meic H.Pigmented villonodular synovitis associated with pathological fracture of the odontoid and atlantoaxial instabilityPPigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovium with a predisposition for the appendicular skeleton. Rarely PVNS can arise from the spine, where this disorder usually presents with localized or radicular pain secondary to involvement of the posterior elements. Th...Atlantoaxial instability; Pigmented villonodular synovitis; Odontoid2007
105 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 10: fusion following decompression in patients with stenosis without spondylolisthesisStandards. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) In situ posterolateral lumbar fusion is not recommended as a treatment option in patients with lumbar stenosis in whom there is n...Fusion; Lumbar spine; Degenerative disease; Lumbar fusion2005
106 Kestle, John R. W.Value of postoperative surveillance imaging in the management of children with some common brain tumorsThe rationale for obtaining surveillance computerized tomography (CT) scans or magnetic resonance (MR) images in pediatric patients with brain tumors is that early detection of recurrence may result in timely treatment and better outcome. The purpose of this study was to investigate the value of sur...Brain neoplasm; Brain tumors; Computerized tomography scanning; Surveillance; Postoperative surveillance1996
107 Couldwell, William T.; Gillespie, David L.Ubiquitous expression of cyclooxygenase-2 in meningiomas and decrease in cell growth following in vitro treatment with the inhibitor celecoxib: potential therapeutic applicationObject. Meningiomas are the second most common symptomatic primary central nervous system tumor in adults. Findings of epidemiological studies link meningiomas with a history of head trauma, indicating a causal relationship between the inflammatory response and meningioma tumorigenesis. Cyclooxygena...2005-09
108 Couldwell, William T.Man for all seasons: W.W. KeenWILLIAM WILLIAMS KEEN was the catalyst for the advent of neurosurgery in the United States. He served in the Civil War and collaborated with Silas Weir Mitchell in studying injuries sustained to the nervous system. These studies culminated in the publication in 1864 of Gunshot Wounds and Other Inj...Brain tumor2002
109 Kestle, John R. W.Change in ventricular size and effect of ventricular catheter placement in pediatric patients with shunted hydrocephalusOBJECTIVE: The multicenter, randomized pediatric cerebrospinal fluid shunt valve design trial found no difference in the rate of shunt failure between a standard valve, a siphon-reducing valve (Delta; Medtronic PS Medical, Goleta, CA), and a flow-limiting valve (Orbis Sigma; Cordis, Miami, FL); ho...Shunt failure; Valve design; Ventricular size; Ventricular catheter placement1999
110 Schmidt, Meic H.Assessment of the reliability of the Enneking and Weinstein-Boriani-Biagini classifications for staging of primary spinal tumors by the spine oncology study groupDespite advances in the treatment of primary spinal tumors in recent years, the with respect to the feasibility of oncologically appropriate surgical treatment and the selection of the optimal surgical approach. These tumors are relatively rare, comprising 11% of all primary musculoskeletal tumors a...2009-01-01
111 Dailey, Andrew T.; Moore, Kevin R.Value of MR neurography for evaluating extraspinal neuropathic leg pain: a pictorial essaySummary: Fifteen patients with neuropathic leg pain referable to the lumbosacral plexus or sciatic nerve underwent high-resolution MR neurography. Thirteen of the patients also underwent routine MR imaging of the lumbar segments of the spinal cord before undergoing MR neurography. Using phased-array...MR neurography; Neuropathic leg pain; Extraspinal; Lumbosacral plexus2001
112 Couldwell, William T.Defining postoperative values for successful resection of prolactinomasWe, as other authors, have noted that late relapse of hyperprolactinemia following apparent successful adenomectomy in women harboring microprolactinomas is not rare.[1-3] On retrospective review of a series of tumors treated at the University of Southern California teaching hospitals, we have foun...Hyperprolactinemia; Microadenoma; Prolactin1996
113 Couldwell, William T.Resolution of an anterior-inferior cerebellar artery feeding aneurysm with the treatment of a transverse-sigmoid dural arteriovenous fistulaThe authors describe a 27-year old man who developed an unruptured anterior-inferior cerebellar artery feeding aneurysm from a transverse-sigmoid dAVF and its subsequent resolution with the treatment of the dAVF. The patient, with a known history of left transverse and sigmoid sinus thrombosis, pres...Aneurysms; Dural Arteriovenous Fistulas; Endovascular therapy; Surgery2007
114 Schmidt, Meic H.; MacDonald, Joel D.; Jensen, Randy L.; Couldwell, William T.Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinusStereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary,...Hypophysial transposition; Hypophysopexy; Pituitary tumors; Stereotactic radiosurgery; Pituitary transposition; Hypopituitarism2003
115 Couldwell, William T.Ventroposterior medial pallidotomy in patients with advanced Parkinson's diseaseIN A PRELIMINARY study, the effects of ventroposterior medial pallidotomy were evaluated in five patients with advanced Parkinson's disease in whom medical therapy had failed. The mean age was 67.0 ? 5.6 years, and t h e mean Hoelin and Yahr stage when "off" was 3.9 ? 1.3. Three patients received u...Pallidotomy; Dyskinesia; Stereotaxy; Postoperative morbidity1995
116 Schmidt, Meic H.; Apfelbaum, Ronald I.Chylorrhea: a rare complication of thoracoscopic discectomy of the thoracolumbar junctionThe thoracic duct along with the cisterna chyli is a major lymphatic pathway near the anterior thoracolumbar spine. Despite the fragile nature of the lymphatic system and its proximity to the spinal column, chylorrhea is rarely encountered by spine surgeons. The authors present a unique case of chyl...Chylous leak; Thoracoscopy; Thoracic spine; Thoracoscopic discectomy; Thoracolumbar junction; Chylorrhea2007
117 Couldwell, William T.Personal perspective: AANS Bulletin's momentum continues: new editor considers peer review, practice survey impactWith this issue, I assume the reins as editor of the AANS Bulletin. I am indebted to James Bean, MD, for his extraordinary efforts in this capacity, as witnessed by review of the recent issues published under his leadership. An important initiative put forth by Dr. Bean and the Bulletin Advisory Boa...2005
118 Couldwell, William T.Medical and surgical management of microprolactinomaA recent report by Colao et al. [1] indicates that a significant proportion of patients harboring prolactinomas treated with cabergoline will have persistence of remission of hyperprolactinemia following withdrawal of the drug. The prolactin and tumor control rates in the study suggest that medical ...Microprolactinoma; Prolactinoma; Cabergolene2004
119 Couldwell, William T.Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. a comparison between staurosporine and tamoxifenWE HAVE PREVIOUSLY demonstrated that the proliferation of established human glioma cell lines correlated with protein kinase C (PKC) activity and that a relatively selective PKC inhibitor, staurosporine, inhibits glioma cell proliferation. The purpose of this study was to determine whether low-passa...Staurosporin; Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Glioma cell lines1993
120 Schmidt, Meic H.; Brockmeyer, Douglas Lee; Dailey, Andrew T.Surgical management of aneurysmal bone cysts of the spineObject. Aneurysmal bone cysts of the spine are benign, highly vascular osseous lesions of unknown origin that may present difficult diagnostic and therapeutic challenges. They are expansile lesions containing thin-walled, blood-filled cystic cavities that cause bone destruction and sometimes spinal ...Aneurysmal bone cyst; Spine tumor; Spinal fusion; Embolization2003
121 Couldwell, William T.Metabolic syndrome: what neurosurgeons should knowThe term metabolic syndrome, first introduced in 1988, has evolved in concept since that time. While the strict definition is subject to ongoing debate, the syndrome generally involves glucose intolerance, obesity, dyslipidemia and high blood pressure, which increase the risk of developing cardiovas...2008-01-01
122 Schmidt, Meic H.Rod derotation techniques for thoracolumbar spinal deformityOBJECTIVE: The operative correction of scoliosis requires multiple intraoperative techniques and tools to achieve an adequate result. Frequently, multiple methods are used to accomplish this, such as rod cantilever techniques, in situ bending, Smith-Petersen and pedicle subtraction osteotomies, clo...2008-01-01
123 Kestle, John R. W.Predicting shunt failure on the basis of clinical symptoms and signs in childrenObject. In evaluating pediatric patients for shunt malfunction, predictive values for symptoms and signs are important in deciding which patients should undergo an imaging study, whereas determining clinical findings that correlate with a low probability of shunt failure could simplify management. ...Pediatric Shunt Design Trial; PSDT; Shunt failure; Shunt malfunction; Clinical signs2001
124 Couldwell, William T.Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase CTHE PROLIFERATION RATES of gliomas may be modulated by the protein kinase C (PKC) signal transduction system. The present study was undertaken to further examine the role of PKC system in growth regulation of gliomas in vitro by measurement of PKC activity over various phases of tumor growth and by ...Protein kinase C; Brain neoplasms; Growth factor; Glioma; Phorbol ester1992
125 Couldwell, William T.Distal ventriculoperitoneal shunt failure secondary to Clostridium Difficile ColitisDistal ventriculoperitoneal shunt obstruction is typically associated with cerebrospinal fluid (CSF) infection, fluid pseudocysts, bowel obstruction, bowel perforation, or improper shunt placement in the abdomen. We describe a unique etiology for distal shunt obstruction secondary to Clostridium dif...Shunt Failure2005-03
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