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Creator | Title | Description | Subject | Date |
101 |
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Gerig, Guido | Structural integrity of the uncinate fasciculus in geriatric depression: relationship with age of onset | Background: The uncinate fasciculus connects limbic structures, such as the hippocampus and amygdala, with frontal regions. This study utilized diffusion tensor imaging to examine the structural integrity of the uncinate fasciculus in late-life depression. Method: 18 elderly depressed and 19 elderly... | | 2007-01-01 |
102 |
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Gerig, Guido | Statistics of populations of images and its embedded objects: driving applications in neuroimaging | Work in progress towards modeling shape statistics of multi-object complexes is presented. Constraints defined by the set of objects such as a compact representation of object shape relationships and correlation of shape changes might have advantages for automatic segmentation and group discriminati... | | 2006-01-01 |
103 |
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Gerig, Guido | Statistical growth modeling of longitudinal DT-MRI for regional characterization of early brain development | A population growth model that represents the growth trajectories of individual subjects is critical to study and understand neurodevelopment. This paper presents a framework for jointly estimating and modeling individual and population growth trajectories, and determining significant regional diffe... | | 2012-01-01 |
104 |
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Gerig, Guido | Statistical shape analysis of brain structures using spherical wavelets | We present a novel method of statistical surface-based morphometry based on the use of non-parametric permutation tests and a spherical wavelet (SWC) shape representation. As an application, we analyze two brain structures, the caudate nucleus and the hippocampus, and compare the results obtained to... | | 2007-01-01 |
105 |
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Gerig, Guido | Subcortical structure segmentation using probabilistic atlas priors | The segmentation of the subcortical structures of the brain is required for many forms of quantitative neuroanatomic analysis. The volumetric and shape parameters of structures such as caudate are employed to characterize a disease or its evolution. This paper presents our fully automatic segmentati... | | 2007-01-01 |
106 |
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Gerig, Guido | Synergy of image analysis for animal and human neuroimaging supports translational research on drug abuse | The use of structural magnetic resonance imaging (sMRI) and diffusion tensor imaging (DTI) in animal models of neurophysiology is of increasing interest to the neuroscience community. In this work, we present our approach to create optimal translational studies that include both animal and human neu... | | 2011-01-01 |
107 |
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Gerig, Guido | Modeling 4D changes in pathological anatomy using domain adaptation: analysis of TBI imaging using a tumor database | Analysis of 4D medical images presenting pathology (i.e., lesions) is significantly challenging due to the presence of complex changes over time. Image analysis methods for 4D images with lesions need to account for changes in brain structures due to deformation, as well as the formation and deletio... | | 2013-01-01 |
108 |
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Gerig, Guido | Minimum description length with local geometry | Establishing optimal correspondence across object populations is essential to statistical shape analysis. Minimizing the description length (MDL) is a popular method for finding correspondence. In this work, we extend the MDL method by incorporating various local curvature metrics. Using local curva... | | 2008-01-01 |
109 |
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Gerig, Guido | Mixed-effects shape models for estimating longitudinal changes in anatomy | | | 2012-01-01 |
110 |
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Gerig, Guido | Modeling longitudinal MRI changes in populations using a localized, information-theoretic measure of contrast | Longitudinal MR imaging during early brain development provides important information about growth patterns and the development of neurological disorders. We propose a new framework for studying brain growth patterns within and across populations based on MRI contrast changes, measured at each time ... | | 2013-01-01 |
111 |
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Gerig, Guido | Normative modeling of early brain maturation from longitudinal DTI reveals twin-singleton differences | Early brain development of white matter is characterized by rapid organization and structuring. Magnetic Resonance diffusion tensor imaging (MR-DTI) provides the possibility of capturing these changes non-invasively by following individuals longitudinally in order to better understand departures fro... | | 2014-01-01 |
112 |
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Gerig, Guido | Noise-induced bias in low-direction diffusion tensor MRI: replication of Monte-Carlo simulation with in-vivo scans | Clinical neuroimaging studies involving diffusion tensor MRI (DTI) require precise estimation of diffusion properties for statistical analysis. Tensor derived measures such as fractional anisotropy (FA) and trace are often analyzed for hypothesis testing. Given the limited scanning time typically av... | | 2007-01-01 |
113 |
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Gerig, Guido | Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury | Available approaches to the investigation of traumatic brain injury (TBI) are frequently hampered, to some extent, by the unsatisfactory abilities of existing methodologies to efficiently define and represent affected structural connectivity and functional mechanisms underlying TI-related pathology.... | | 2012-01-01 |
114 |
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Gerig, Guido | Statistical group differences in anatomical shape analysis using Hotelling T2 Metric | Shape analysis has become of increasing interest to the neuroimaging community due to its potential to precisely locate morphological changes between healthy and pathological structures. This manuscript presents a comprehensive set of tools for the computation of 3D structural statistical shape anal... | | 2007-01-01 |