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101 Schmidt, Meic H.; Schmidt, Richard H.Nerve sheath tumors involving the sacrumNerve sheath tumors that involve the sacrum are rare. Delayed presentation is common because of their slow-growing nature, the permissive surrounding anatomical environment, and nonspecific symptoms. Consequently, these tumors are usually of considerable size at the time of diagnosis. The authors di...Nerve sheath tumor; Schwannoma2003
102 Schmidt, Meic H.Repeated operations for infiltrative low-grade gliomas without intervening therapyProgression of infiltrative low-grade gliomas (LGGs) has been reported previously. The limitations of such studies include diverse histological grading systems, intervening therapy, and the lack of histological confirmation of malignant tumor progression. The aim of this study was to determine tumo...Infiltrative low-grade gliomas; LGG; Tumor progression; Repeated operations; Tumor recurrence2003
103 Couldwell, William T.Zones of approach for craniofacial resection: minimizing facial incisions for resection of anterior cranial base and paranasal sinus tumorsAnterior cranial base tumors are surgically resected with combined craniofacial approaches that frequently involve disfiguring facial incisions and facial osteotomies. The authors outline three operative zones of the anterior cranial base and paranasal sinuses in which tumors can be resected with th...Anatomic study; Anterior cranial base; Cranial base surgery; Craniofacial surgery; Minimally invasive2003
104 Schmidt, Meic H.Diffuse large B-cell lymphoma presenting as a sacral tumorPrimary lymphomas of the sacrum are rare tumors, reported only in a few cases in the literature. The authors describe two patients with diffuse large B-cell lymphomas presenting as a sacral tumor. In the first case a 52-year-old man presented with progressive back pain, bilateral radicular pain, an...B-cell lymphoma; Sacral tumor2003
105 Schmidt, Meic H.; Apfelbaum, Ronald I.Cervical spinal metastasis: anterior reconstruction and stabilization techniques after tumor resectionObject. In a review of the literature, the authors provide an overview of various techniques that have evolved for reconstruction and stabilization after resection for metastatic disease in the subaxial cervical spine. Methods. Reconstruction and stabilization of the cervical spine after vertebral...Cervical spine reconstruction; Metastasis; Spine tumor; Corpectomy; Stabilization technique; Vertebral body2003
106 Schmidt, Meic H.; Kestle, John R. W.Treatment of metastatic spinal epidural disease: a review of the literatureObject. Spinal cord compression is one of the most dreaded complications of metastatic cancer. It can lead to a number of sequelae, including pain, spinal instability, neurological deficits, and a reduction in the patient's quality of life. Except in selected circumstances, treatment is palliative. ...Spinal cord compression; Metastasis; Radiation therapy; Stereotactic radiosurgery2003
107 Schmidt, Meic H.Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome ProjectIn many new clinical trials of patients with malignant gliomas surgical intervention is incorporated as an integral part of tumor-directed interstitial therapies such as gene therapy, biodegradable wafer placement, and immunotherapy. Assessment of toxicity is a major component of evaluating these no...Perioperative complications; Neurological outcomes; Glioma Outcome Project2003
108 Schmidt, Meic H.Embolization of sacral tumorsThe management of sacral tumors is challenging because of difficulties in accessing the lesion, the high rate of local recurrence, extensive vascularity causing significant intraoperative blood loss, resistance to radiation therapy, and risk of malignant transformation. Although surgery is the main ...Sacral tumor2003
109 Couldwell, William T.; Orlandi, Richard R.; Jensen, Randy L.Endoscopic-assisted craniofacial resection of esthesioneuroblastoma: minimizing facial incisionsThe surgical management of esthesioneuroblastomas has traditionally been craniofacial resection, which combines a bifrontal craniotomy with a transfacial approach. The latter usually involves a disfiguring facial incision, mid-facial degloving, lateral rhinotomy, and/or extensive facial osteotomies...Esthesioneuroblastoma; Craniofacial resection; Endoscope; Craniofacial surgery; Minimally invasive2003
110 Kestle, John R. W.Lack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trialObject. Endoscopically assisted ventricular catheter placement has been reported to reduce shunt failure in uncontrolled series. The authors investigated the efficacy of this procedure in a prospective multicenter randomized trial. Methods. Children younger than 18 years old who were scheduled for t...Ventriculoperitoneal shunt; Shunt insertion; Shunt failure2003
111 Couldwell, William T.; Schmidt, Meic H.; MacDonald, Joel D.; Jensen, Randy L.Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinusStereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary,...Pituitary tumor; Cavernous sinus; Hypopituitarism; Stereotactic radiosurgery; Transsphenoidal surgery; Pituitary transposition2003
112 Schmidt, Meic H.Spinal meningiomas: surgical management and outcomeAdvances in imaging and surgical technique have improved the treatment of spinal meningiomas; these include magnetic resonance imaging, intraoperative ultrasonography, neuromonitoring, the operative microscope, and ultrasonic cavitation aspirators. This study is a retrospective review of all patient...Spinal meningioma; Spinal tumor; Intradural; Extramedullary2003
113 Schmidt, Meic H.Diagnosis and management of sacral Tarlov cystsPerineurial (Tarlov) cysts are meningeal dilations of the posterior spinal nerve root sheath that most often affect sacral roots and can cause a progressive painful radiculopathy. Tarlov cysts are most commonly diagnosed by lumbosacral magnetic resonance imaging and can often be demonstrated by com...Tarlov cysts; Meningeal dilations; Spinal lesion; Outcome2003
114 Schmidt, Meic H.; MacDonald, Joel D.; Jensen, Randy L.; Couldwell, William T.Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinusStereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary,...Hypophysial transposition; Hypophysopexy; Pituitary tumors; Stereotactic radiosurgery; Pituitary transposition; Hypopituitarism2003
115 Couldwell, William T.Pituitary apoplexy: diagnosis and managementPituitary apoplexy, an uncommon complication of pituitary adenomas, was first decribed in 1898 when pearce Bailey reported hemorrhage into a pituitary adenoma in a 50 year old man with acromegaly. The patient presented with sudden onset of headache, nausea, vomiting, fever, oculomotor palsies, and v...Pituitary Apoplexy; Pituitary adenoma; Transsphenoidal surgery2003
116 Kestle, John R. W.Tracking resident work hours: available software is not yet ideal, but it's helpfulAn ideal system would be completely passive and would allow more detailed tracking of activity inside the hospital. A new reality began July 1. We are all now responsible for tracking our residents' work hours and ensuring compliance with the new regulations mandated by the Accreditation Council fo...Resident work hours; Tracking; TimeClock system2003
117 Couldwell, William T.Transsphenoidal microsurgical treatment of Cushing disease: postoperative assessment of surgical efficacy by application of an overnight low-dose dexamethasone suppression testObject. Transsphenoidal adenomectomy with resection of a defined pituitary adenoma has been the treatment of choice for CD for the last 30 years. Surgical resection, however, may not always result in long-term remission of CD. This is particularly important in light of the high risk of morbidity and...2003-01-01
118 Couldwell, William T.Assessment of long-term remission of acromegaly following surgeryObject. The criteria for remission of acromegaly following transsphenoidal adenoma resection are in evolution. In the present study the authors evaluate the utility of predicting long-term remission by reference to a single fasting growth hormone (GH) level on the 1st postoperative day. Methods. A ...Acromegaly; Pituitary adenoma; Transsphenoidal surgery; Growth hormone; Insulin-like growth factor I2003-01-01
119 Couldwell, William T.; Gottfried, Oren N.Surgical management of posterior petrous meningiomasPosterior petrous meningiomas (commonly termed posterior pyramid meningiomas and/or meningiomas of the posterior surface of the petrous pyramid) are the most common meningiomas of the posterior cranial fossa. They are located along the posterior surface of the temporal bone in the region of the cere...2003-01-01
120 Couldwell, William T.; Gottfried, Oren N.Too many? Too few. New study reveals current trends in U. S. neurosurgical workforceRemarkable changes in the neurosurgical specialty have taken place in the past 15 years. While advances in basic science have occurred and new technologies and therapies have proliferated, other, less propitious factors-such as the promises (some might say false promises) and hopes of managed care-h...2003-01-01
121 Couldwell, William T.Communication between malignant glioma cells and vascular endothelial cells through gap junctionsObject. Extensive invasion and angiogenesis are hallmark features of malignant gliomas. Communication between malignant glioma cells and surrounding astrocytes occurs, resulting in transformation of the astrocytic phenotype. In the present study, the authors examined whether malignant glioma cells a...2003-01-01
122 Couldwell, William T.Increased invasive capacity of connexin43-overexpressing malignant glioma cellsObject. Malignant glioma cells, similar to astrocytes, express connexin43 (Cx43) universally but at widely varied levels. Data from previous studies have demonstrated that malignant glioma cells form functional gap junction channels among themselves as well as with astrocytes and that such a communi...2003-12
123 Couldwell, William T.Porous polyethylene implant for cranioplasty and skull base reconstructionObject. Cranial reconstruction after skull base surgery is important for restoration of function and cosmesis. The authors describe their experience with the Medpor porous polyethylene implant for cosmetic cranioplasty and reconstruction after skull base surgery. Methods. Medpor, a biocompatible i...2004
124 Schmidt, Meic H.Role of thoracoscopic spinal surgery in the management of pyogenic vertebral osteomyelitisStudy Design. Case report, operative technique. Objectives. Vertebral osteomyelitis is frequently associated with elderly and debilitated patients who have significant medical comorbidities. If surgical debridement is contemplated, an open anterior approach like a thoracotomy can be associated with...Thoracoscopic spinal surgery; Pyogenic vertebral osteomyelitis2004
125 Schmidt, Meic H.Cavernous hemangioma of the skull presenting with subdural hematomaCavernous hemangioma of the calvaria is a very rare disease, and patients usually present with headaches or a visible skull deformity. Few reports of patients presenting with intradiploic or epidural hemorrhages are found in the literature. No case of an intradural hemorrhage from a cavernous hemang...Calvaria; Cavernous hemangioma2004
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