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Creator | Title | Description | Subject | Date |
| 101 |
 |
Normann, Richard A. | Statistical encoding model for a primary motor cortical brain-computer interface | A number of studies of the motor system suggest that the majority of primary motor cortical neurons represent simple movement-related kinematic and dynamic quantities in their time-varying activity patterns. An example of such an encoding relationship is the cosine tuning of firing rate with respect... | Discrete Distribution; LN Model; Neural Decoding; Neuroprosthetics; Sequential Monte-Carlo Filter | 2005 |
| 102 |
 |
Gesteland, Raymond F.; Atkins, John F.; Wills, Norma M. | rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshift | Base pairing between the 3' end of 16S rRNA and mRNA is shown to be important for the programmed -1 frameshifting utilized in decoding the Escherichia coli dnaX gene. This pairing is the same as the Shine-Dalgarno pairing used by prokaryotic ribosomes in selection of translation initiators, but for ... | Frameshifting; Escherichia coli; Binding Sites; Base Composition | 1994 |
| 103 |
 |
Horch, Kenneth W. | Selective stimulation of peripheral nerve fibers using dual intrafascicular electrodes | We have studied activation of newe fibers by pairs of Pt-Ir wire electrodes implanted within single fascicles of the nerve innervating the gastrocnemius muscle in cats. The purpose of this study was to determine if these intrafascicular electrodes can activate nerve fibers in different fascicles... | Functional electrical stimulation; Intrafascicular stimulation; Silicon electrode array | 1993 |
| 104 |
 |
Gesteland, Raymond F. | Simian virus 40-specific polypeptides in Ad2+ND4- infected cells | A comparison of the proteins synthesized in human cells at late times after infection with adenovirus (Ad2) and with the adeno-simian virus 40 (SV40) hybrid viruses revealed polypeptides of 30,000 and 92,000 molecular weight specific for the hybrid viruses Ad2+ND1 and Ad2+ND4, respectively. Cell-fre... | Molecular Weight; Peptide Biosynthesis; RNA, Messenger; Viral Proteins | 1976 |
| 105 |
 |
Christensen, Douglas A.; Herron, James N. | Optical immunoassay systems based upon evanescent wave interactions | Immunoassays based upon evanescent wave interactions are finding increased biosensing application. In these devices, the evanescent tail associated with total internal reflection of an incident beam at the substrate/solution interface provides sensitivity for surface-bound proteins over bulk molec... | Diagnostics; Evanescence; Planar waveguides; Human chorionic gonadotropin (hCG) | 1996 |
| 106 |
 |
Christensen, Douglas A. | Interface of forest and agriculture in nonpoint pollution control | Management practices of agriculture, including conservation and tillage options, recently have received a great deal of attention with respect to their impact upon the environment. Research efforts have focused both on the direct impacts of reduced on-site productivity resulting from the erosion of ... | Suspended sediment; Channel erosion; Silviculture | 1983 |
| 107 |
 |
Horch, Kenneth W. | Tracking changes in action potential shapes in chronic multi-unit intrafascicular recordings using neural network pattern recognition techniques | A novel scheme is proposed to train an Artificial Neural Network (A") classifier, on a repeated basis, in order to track temporal changes in the shapes of the action potentials recorded through chronically implanted intrafascicular electrodes. This scheme uses classification results of the ANN Clas... | Intrafascicular electrodes; Artificial neural network | 1994 |
| 108 |
 |
Christensen, Douglas A. | Effects of increased energy prices on U.S. agriculture: an econometric approach | Although the contents of this manuscript remain the responsibility of the authors, we wish to thanks a group of reviewers for the time and conscientious effort they put forth to solidify this final draft. Andrew Morton, Brian Holding, Wesley Buchele, and Arnold Paulsen deserve much credit for their ... | Energy prices | 1981 |
| 109 |
 |
Horch, Kenneth W. | Control of ankle position using neural feedback | This paper describes a closed loop control system that uses afferent neural activity from muscle spindle fibers as feedback for controlling ankle position. The gastrocnemius muscle was stimulated through a dual channel intrafascicular electrode implanted in a fascicle of the tibial nerve. Dual cha... | Neuromuscular stimulation; Peripheral nerve; Joint angle | 1994 |
| 110 |
 |
Gesteland, Raymond F.; Atkins, John F. | Evolutionary specialization of recoding: frameshifting in the expression of S. cerevisiae antizyme mRNA is via an atypical antizyme shift site but is still +1 | An autoregulatory translational shift to the +1 frame is required for the expression of ornithine decarboxylase antizyme from fungi to mammals. In most eukaryotes, including all vertebrates and a majority of the studied fungi/yeast, the site on antizyme mRNA where the shift occurs is UCC-UGA. The me... | Antizyme; ODC; Polyamines; Frameshifting | 2006 |
| 111 |
 |
Normann, Richard A. | Effects of GABA and related drugs on horizontal cells in the isolated turtle retina | The role of GABA in the outer plexiform layer of the turtle retina has been examined by intracellular recordings from L- and C-type horizontal cells in the isolated retina preparation. GABA (1-5 mM) slightly depolarized the L-type horizontal cells, reduced the amplitude of their photoresponses, and ... | Retina; Horizontal Cells; Synapse; Negative Feedback; GABA; Turtle | 1990 |
| 112 |
 |
Gesteland, Raymond F.; Atkins, John F. | Origin and destiny of adenovirus proteins | Lytic infection of human cells by adenovirus proceeds by a temporal expression of genes. Classically two phases have been defined: an early phase, which includes events occurring before the onset of DNA synthesis (8 hours), and a late phase, including events whose existence depends on the onset of... | Protein Biosynthesis; DNA, Viral; Adenoviridae; RNA, Viral; Time Factors | 1975 |
| 113 |
 |
Gesteland, Raymond F. | Pattern of protein synthesis in monkey cells infected by simian virus 40 | After infection of several permanent monkey cell lines by simian virus 40 (SV40), four additional protein bands can be detected by simple sodium dodecyl sulfate-polyacrylamide gel electrophoresis of whole-cell extracts. These bands appear only after the onset of viral deoxyribonucleic acid (DNA) syn... | Monkeys; Simian virus 40; Peptides; DNA, Viral/biosynthesis | 1972 |
| 114 |
 |
Horch, Kenneth W. | Action potential classification with dual channel intrafascicular electrodes | Using recordings of peripheral nerve activity made with carbon fiber intrafascicular electrodes, we compared the performance of three different recording techniques (single channel, differential, and dual channel) and four different unit classification methods (linear discriminant analysis, temp... | Carbon fiber intrafascicular electrodes; Dual channel recording | 1994 |
| 115 |
 |
Christensen, Douglas A.; Horch, Kenneth W. | Experience with the first three years of an accelerated dual-degree program in biomedical engineering | Our Department of Bioengineering has instituted a pilot program aimed at helping a select group of highly qualified students obtain both bachelor's and master's degrees in an accelerated timeframe-approximately four years from the beginning of their university studies. A key element of this progra... | Accelerated; Dual-degrees; Education | 2004 |
| 116 |
 |
Horch, Kenneth W.; Tuckett, Robert P.; Burgess, Paul Richard | Neural signal for skin indentation depth. II. Steady indentations | The glabrous skin of the monkey's hand was stimulated with a waveform that indented the skin at a rate of 0.4 mm/set, held the skin steadily or nearly steadily indented for 12 set or longer, and then retracted back to the starting position. Recordings were made of activity in single afferent fibe... | Skin; Indentation; Nerve impulses | 1983 |
| 117 |
 |
Christensen, Douglas A. | Multiple sensor optical thermometry system for application in clinical hyperthermia | The thermometry system described is based upon the temperature dependence of the band edge absorption of infrared light in GaAs crystal. The design of the thermometry was completed, and the system was subjected to an extensive evaluation, including testing with tissue phantoms and microwave applic... | Thermometry; Hyperthermia applicator; Phantom tests | 1984-01 |
| 118 |
 |
Normann, Richard A.; Horch, Kenneth W.; Cha, Kichul | Mobility performance with a pixelized vision system | A visual prosthesis, based on electrical stimulation of the visual cortex, has been suggested as a means for partially restoring functional vision in the blind. The prosthesis would create a pixelized visual sense consisting of punctate spots of light (phosphenes). The present study investigated the... | Visual Prosthesis; Mobility; Phosphene Simulator | 1992 |
| 119 |
 |
Gesteland, Raymond F.; Atkins, John F.; Weiss, Robert B. | Slippery runs, shifty stops, backward steps and forward hops: -2, -1, +1, +2, +5 and +6 Ribosomal frameshifting | Frameshift mutations frequently express residual levels of gene activity; that is, they are often leaky. This leakiness can be used as a tool to define the functional components that affect the reading frame during gene expression. Recent technological advances in the capability to efficiently bu... | Molecular Sequence Data; Mutation; RNA, Transfer; Frameshifting | 1987 |
| 120 |
 |
Horch, Kenneth W. | Intrafascicular electrodes for nerve stimulation | We have designed a new type of intrafascicular, implanted electrode for stimulating peripheral nerves to elicit muscle contraction. The electrode requires low current to stimulate the nerve fibers, provides a fine control of muscular force, and causes little or no tissue reaction. it is of potential... | Intrafascicular electrodes; Peripheral nerve; Neural recordings | 1988 |
| 121 |
 |
Christensen, Douglas A. | Introduction to biomedical engineering: biomechanics and bioelectricity - part I | Intended as an introduction to the field of biomedical engineering, this book covers the topics of biomechanics (Part I) and bioelectricity (Part II). Each chapter emphasizes a fundamental principle or law, such as Darcy's Law, Poiseuille's Law, Hooke's Law, Starling's law, levers and work in the a... | Biological membranes; Poiseuille's law; Hooke's law; Starling's law of the heart; Matlab | 2009 |
| 122 |
 |
Christensen, Douglas A.; Andrade, Joseph D. | Improved sensitivity in ellipsometry of thin biochemical films by employing sublayers | Ellipsometry is widely used for investigating the optical properties of thin films on planar substrates, including films of adsorbed proteins or polymers. The average thickness and effective refractive index of the adsorbed layer are calculated by measuring the A and ¥ ellipsometry parameters. Unfo... | Biochemical films; SiO2 sublayer | 1990 |
| 123 |
 |
Christensen, Douglas A. | Pulsed Schlieren system for visualizing beams from phased-array HIFU applicators | We have assembled a Schlieren system for imaging the beam patterns from HIFU transducers in water to verify the desired beam focusing and direction. It consists of a high power (65 mW) short-pulse (as short as 2 ns) laser emitting at 658 nm, a beam expander/spatial filter, water tank, 400 Jim round ... | Ultrasound beam patterns; Pulsed laser; Wavefronts | 2007 |
| 124 |
 |
Horch, Kenneth W. | Separation of action potentials in multiunit intrafascicular recordings | Classification of action potentials in multiunit recordings was based on the use of various types of features to uniquely characterize action potentials from different cells. We compared classification results obtained using three types of descriptive features: digitized data points, amplitude and ... | Long-term implantable intrafascicular electrodes; Nerve recordings; Simulated neural data | 1992 |
| 125 |
 |
Christensen, Douglas A.; Horch, Kenneth W. | Accelerated dual-degree BS/MS program - experience with the first three years | We have initiated a pilot program that accelerates the studies of a small group of highly qualified students early in their college careers and allows them to earn both a bachelor's degree and a master's degree in about four years after starting college. It does this by introducing them early to res... | Accelerated dual-degree program | 2004 |
