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101 Gerig, GuidoA framework for longitudinal data analysis via shape regressionTraditional longitudinal analysis begins by extracting desired clinical measurements, such as volume or head circumference, from discrete imaging data. Typically, the continuous evolution of a scalar measurement is estimated by choosing a 1D regression model, such as kernel regression or fitting a p...2012-01-01
102 Rondina, Matthew ThomasEmerging evidence for platelets as immune and inflammatory effector cellsWhile traditionally recognized for their roles in hemostatic pathways, emerging evidence demonstrates that platelets have previously unrecognized, dynamic roles that span the immune continuum. These newly recognized platelet functions, including the secretion of immune mediators, interactions with e...2014-01-01
103 Gerig, GuidoPatient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injuryAvailable approaches to the investigation of traumatic brain injury (TBI) are frequently hampered, to some extent, by the unsatisfactory abilities of existing methodologies to efficiently define and represent affected structural connectivity and functional mechanisms underlying TI-related pathology....2012-01-01
104 Gerig, GuidoMeasures for validation of DTI tractographyThe evaluation of analysis methods for diffusion tensor imaging (DTI) remains challenging due to the lack of gold standards and validation frameworks. Significant work remains in developing metrics for comparing fiber bundles generated from streamline tractography. We propose a set of volumetric and...2012-01-01
105 Gerig, GuidoStatistical growth modeling of longitudinal DT-MRI for regional characterization of early brain developmentA population growth model that represents the growth trajectories of individual subjects is critical to study and understand neurodevelopment. This paper presents a framework for jointly estimating and modeling individual and population growth trajectories, and determining significant regional diffe...2012-01-01
106 Gerig, GuidoAnalysis of diffusion tensor imaging for subjects with Down SyndromeAuthors: Neda Sadeghi1, Clement Vachet1, Marcel Prastawa1, Julie Korenberg1, Guido Gerig1 Institutions: 1University of Utah, Salt Lake City, UT Introduction: Down syndrome (DS) is the most common chromosome abnormality in humans. It is typically associated with delayed cognitive development and phys...2013-01-01
107 Gerig, GuidoA longitudinal structural MRI study of change in regional contrast in Autism Spectrum DisorderAuthors: Avantika Vardhan1, Joseph Piven2, Marcel Prastawa3, Guido Gerig3 Institutions: 1Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, United States, 2Dept of Psychiatry, UNC School of Medicine, Chapel Hill, NC, 3University of Utah, Salt Lake City, UT Introduction: ...2013-01-01
108 Gerig, GuidoEfficient probabilistic and geometric anatomical mapping using particle mesh approximation on GPUsDeformable image registration in the presence of considerable contrast differences and large size and shape changes presents significant research challenges. First, it requires a robust registration framework that does not depend on intensity measurements and can handle large nonlinear shape variati...2011-01-01
109 Gerig, GuidoBrain volumes in psychotic youth with schizophrenia and mood disordersBackground: We sought to test the hypothesis that deficits in grey matter volume are characteristic of psychotic youth with early-onset schizophrenia-spectrum disorders (EOSS) but not of psychotic youth with early-onset mood disorders (EOMD). Methods: We used magnetic resonance imaging to examine br...2010-01-01
110 Gerig, GuidoSynergy of image analysis for animal and human neuroimaging supports translational research on drug abuseThe use of structural magnetic resonance imaging (sMRI) and diffusion tensor imaging (DTI) in animal models of neurophysiology is of increasing interest to the neuroscience community. In this work, we present our approach to create optimal translational studies that include both animal and human neu...2011-01-01
111 Gerig, GuidoQuantifying regional growth patterns through longitudinal analysis of distances between multimodal MR intensity distributionsQuantitative analysis of early brain development through imaging is critical for identifying pathological development, which may in turn affect treatment procedures. We propose a framework for analyzing spatiotemporal patterns of brain maturation by quantifying intensity changes in longitudinal MR i...2012-01-01
112 Jaskowski, Troy D.Neuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice culturesBackground: Anti-Hu and anti-Ri antibodies are paraneoplastic immunoglobulin (Ig)G autoantibodies which recognize cytoplasmic and nuclear antigens present in all neurons. Although both antibodies produce similar immunohistological labeling, they recognize different neuronal proteins. Both antibodies...2014-01-01
113 Gur, YanivAssessment of white matter microstructure in stroke patients using NODDIDiffusion weighted imaging (DWI) is widely used to study changes in white matter following stroke. In various studies employing diffusion tensor imaging (DTI) and high angular resolution diffusion imaging (HARDI) modalities, it has been shown that fractional anisotropy (FA), me...2014-01-01
114 Gerig, GuidoWhite matter microstructure and atypical visual orienting in 7 month-olds at risk for autismObjective: The authors sought to determine whether specific patterns of oculo-motor functioning and visual orientingcharacterize 7-month-old infants who later meet criteria for an autism spectrum disorder (ASD) and to identify the neural correlates of these behaviors. Method:Data were collected from...2013-01-01
115 Gerig, GuidoReduced relationship to cortical white matter volume revealed by Tractography-based segmentation of the corpus callosum in young children with developmental delayObjective: The corpus callosum is the primary anatomical substrate for inter-hemispheric communication, which is important for a range of adaptive and cognitive behaviors in early development. Previous studies that have measured the corpus callosum in developmental populations have been limited by t...2006-01-01
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