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CreatorTitleDescriptionSubjectDate
76 Digre, Kathleen B.; Kleinschmidt, Julia J.; Hanover, RitaIdiopathic intracranial hypertension. Relationship to depression, anxiety, and quality of lifeOBJECTIVE: To explore the incidence of depression and anxiety and to measure quality of life in women with idiopathic intracranial hypertension (IIH), a matched group cross-sectional study was conducted. Women with IIH (n = 28) were compared with control groups of weight- and age-matched women not d...Intracranial Hypertension; Depression; Anxiety; Quality of Life2000-01-25
77 Baehr, Wolfgang; Thulin, CraigImmunolocalization and divergent roles of phosducin and phosducin-like protein in the retinaPURPOSE: These investigations were undertaken to compare and contrast the roles of phosducin and phosducin-like protein in the retina. METHODS: Phosducin and phosducin-like protein were compared in an in vitro assay measuring their inhibition of transducin binding to light-activated rhodopsin. The t...Antibody Specificity; Protein Binding; Rod Outer Segments1999
78 Baehr, WolfgangIn vitro isoprenylation and membrane association of mouse rod photoreceptor cGMP phosphodiesterase alpha and beta subunits expressed in bacteriaWe investigated the specificity of CAAX box-related isoprenylation of rod photoreceptor cGMP phosphodiesterase (PDE) subunits expressed in bacteria and the consequences of this modification on rod disk membrane association. Full-length cDNA sequences of the alpha and beta subunits of mouse PDE, inse...Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data1992
79 Frederick, Jeanne M.Inactivity of human β,β-carotene-9′, 10-′dioxygenase (BCO2) underlies retinal accumulation of the human macular carotenoid pigmentThe macula of the primate retina uniquely concentrates high amounts of the xanthophyll carotenoids lutein, zeaxanthin, and meso-zeaxanthin, but the underlying biochemical mechanisms for this spatial- and species-specific localization have not been fully elucidated. For example, despite abundant reti...2014-01-01
80 Frederick, Jeanne M.Inhibitors of metalloendoprotease activity prevent K+-stimulated neurotransmitter release from the retina of Xenopus laevis.Metalloendoprotease activity was identified in retinal homogenates using a synthetic fluorogenic metalloendoprotease substrate and specific metalloendoprotease inhibitors. The requirement of metalloendoprotease activity in neurotransmitter release was examined during the depolarization-induced relea...Neuromuscular Junction; Neurotransmitter Agents; Membrane Fusion1984
81 Warner, Judith E. A.Intermittent reversal of Complete Ptosis-EganWarnerCASE REPORT: Ptosis secondary to dense oculomotor pareses generally improves over several months, but intermittent elevation of the eyelid has not been reported. The Author's describe two patients who demonstrated intermittent involuntary monocular eyelid elevation in an eye with complete ptosis cau...Eyelids; Ophthalmoplegia; Intraoperative Complications2006
82 Olson, Randall J.; Crandall, Alan S.; Caldwell, Karin D.; Jensen, Michael K.Intraoperative crystallization on the intraocular lens surfacePURPOSE: To report a physician survey, laboratory studies, and clinical observations of intraoperative crystallization on the surface of the intraocular lens (IOL). METHOD: We sent a survey to all ophthalmologists in the states of Wyoming, Idaho, Montana, Utah, and Colorado asking whether crystalliz...Cataract Extraction; Intraoperative Complications; Risk Factors1998-08
83 Olson, Randall J.; Crandall, Alan S.; Mamalis, NickIntraoperative miotics and posterior capsular opacification following phacoemulsification with intraocular lens insertionBACKGROUND AND OBJECTIVES: Posterior capsular opacification (PCO) is a frequent complication following phacoemulsification with intraocular lens (IOL) implantation. A series of consecutive patients receiving capsular bag-fixated, silicone IOL implants were assessed for both incidence of PCO and the ...Intraocular Lens; Nd:YAG Laser Capsulotomy; Miochol; Miostat; Phacoemulsification; Posterior Capsular Opacification1997-11
84 Kriesel, John D.; Gooch, Willis M.; Pavia, Andrew T.Invasive sinonasal disease due to Scopulariopsis candida: case report and review of scopulariopsosis.Sinonasal infection with fungi of the order Mucorales--termed mucormycosis or zygomycosis--is sometimes seen in immunosuppressed patients, including those with diabetic ketoacidosis and malignancy. We describe a case of invasive sinonasal infection with Scopulariopsis candida (not among the Mucorale...Granulocyte Colony-Stimulating Factor; Itraconazole; Maxillary Sinus1994
85 Fuhrmann, Sabine; Zhang, Jianmin; Vetter, Monica L.Investigation of Frizzled-5 during embryonic neural development in mouseCellular and tissue--tissue interactions regulate development of the central nervous system (CNS) and a paramount question is what is the nature of the signals involved in these interactions. The vertebrate eye represents an excellent and challenging CNS model because it contains multiple cell and ...Mouse; Eye; Optic cup; Morphogenesis; Retina; Lens; Wnt; Frizzled; Pituitary2008
86 Baehr, WolfgangIsolation and characterization of cGMP phosphodiesterase from bovine rod outer segmentsA simple purification method has been developed for isolation of bovine cGMP phosphodiesterase from photoreceptor rod outer segments. The enzyme is peripherally membrane bound in its native state and is present in relatively high concentrations. In the bovine photoreceptors its molar ratio to rhodop...Enzyme Activation; Macromolecular Substances; Trypsin/pharmacology1979
87 Angelucci, AlessandraLayer-specific programs of development in neocortical projection neuronsHow are long-range axonal projections from the cerebral cortex orchestrated during development? By using both passively and actively transported axonal tracers in fetal and postnatal ferrets, we have analyzed the development of projections from the cortex to a number of thalamic nuclei. We report th...Axonal Transport; Efferent Pathways; Brain Mapping1995
88 Baehr, WolfgangLecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liverLecithin-retinol acyltransferase (LRAT), an enzyme present mainly in the retinal pigmented epithelial cells and liver, converts all-trans-retinol into all-trans-retinyl esters. In the retinal pigmented epithelium, LRAT plays a key role in the retinoid cycle, a two-cell recycling system that replenis...Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Microscopy, Fluorescence2004
89 Olson, Randall J.Legacy AdvanTec and Sovereign WhiteStar: a wound temperature studyPURPOSE: To assess the wound temperature of the Sovereign WhiteStar (S-WS) (AMO) and Legacy AdvanTec (L-ADV) (Alcon) phacoemulsification systems. SETTING: John A. Moran Eye Center, Health Sciences Center, University of Utah, Salt Lake City, Utah, USA. METHODS: Phacoemulsification using 20-gauge, 30-...Eye Burns; Wound Temperature; Phacoemulsification Systems2004-05
90 Baehr, WolfgangLight-dependent changes in G-protein binding to ROS membranes in intact Bufo retinasLight-dependent changes in the binding of G-protein were analyzed in outer segment disk membranes obtained from photoreceptors of the toad (Bufo marinus) retina. Isolated, intact retinas, incubated in oxygenated Ringer's solution at 23 +/- 1 degree C, were subjected to various conditions of illumina...Centrifugation, Density Gradient; Membranes; Adaptation, Physiological1986
91 Baehr, WolfgangLight-dependent redistribution of visual arrestins and transducin subunits in mice with defective phototransductionPURPOSE: The light-dependent redistribution of phototransduction components in photoreceptor cells plays a role in light adaptation. Upon illumination, rod and cone arrestins (Arr and cArr) translocate from the inner to the outer segments while transducin subunits (Talpha, Tbetagamma) translocate in...Phototransduction; Protein Kinases; Rhodopsin Kinase2003
92 Normann, Richard A.; Branner, AlmutLong-term stimulation and recording with a penetrating microelectrode array in cat sciatic nerveWe studied the consequences of long-term implantation of a penetrating microelectrode array in peripheral nerve over the time course of 4-6 mo. Electrode arrays without lead wires were implanted to test the ability of different containment systems to protect the array and nerve during contractions o...Cats; Microelectrodes; Prosthesis Implantation; Sciatic Nerve2004
93 Zhang, KangLoss of ER retention and sequestration of the wild-type ELOVL4 by Stargardt disease dominant negative mutantsPURPOSE: Mutations in ELOVL4, a member of the fatty acid elongase (ELO) family, are responsible for autosomal dominant Stargardt-like macular degeneration. The specific role of ELOVL4 in photoreceptors and the degenerative events induced by dominant ELOVL4 mutations are not well understood. As a fir...Macular Degeneration; Transcription Factor CHOP; Molecular Chaperones2005
94 Bernstein, Paul S.; Gellermann, WernerMacular pigment Raman detector for clinical applicationsClinical studies of carotenoid macular pigments (MP) have been limited by the lack of noninvasive, objective instruments. We introduce a novel noninvasive optical instrument, an MP Raman detector, for assessment of the carotenoid status of the human retina in vivo. The instrument uses resonant excit...Diagnosis, Computer-Assisted; Equipment Failure Analysis; Sensitivity and Specificity2004
95 Olson, Randall J.Mathematical description of causative factors and prevention of elevated intraocular pressure after keratoplastyIn keratoplasty with grafts the same size as the recipient bed, tight sutures and thick recipient corneal periphery distort the angle and may collapse the filtering meshwork. This can cause very high postoperative pressures, which can be avoided by the use of donor grafts larger than the recipient b...Keratoplasty; Trabecular Collapse; Angle Disrottion; Elevated Pressure; Aphakia; Mathematics1977-12
96 Fu, YingbinMechanism of reductive activation of potato tuber ADP-glucose pyrophosphorylase.The potato tuber (Solanum tuberosum L.) ADP-glucose pyrophosphorylase activity is activated by a incubation with ADP-glucose and dithiothreitol or by ATP, glucose- 1-phosphate, Ca2+, and dithiothreitol. The activation was accompanied by the appearance of new sulfhydryl groups as determined with 5, 5...Glucosephosphates; Enzyme Activation; Adenosine Triphosphate1998
97 Baehr, WolfgangMetabolism and transactivation activity of 13,14-dihydroretinoic acidThe metabolism of vitamin A is a highly regulated process that generates essential mediators involved in the development, cellular differentiation, immunity, and vision of vertebrates. Retinol saturase converts all-trans-retinol to all-trans-13,14-dihydroretinol (Moise, A. R., Kuksa, V., Imanishi, Y...Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Retinoid X Receptors2005
98 Olson, Randall J.Microphaco updateMicrophacoemulsification, or cataract surgery using ultrasound through two small stab incisions. Wound burn is now not a problem with AMO's Sovereign system plus Whitestar technology.Microphacoemulsification; Wound Burn; Cataract Extraction2002
99 Kriesel, John D.Miliary Tuberculosis and the postpartum stateIn 1985, a resurgence of tuberculosis began in the United States. In conjunction with this resurgence, there has been an increase in the number of atypical presentations of the disease. We recently treated a patient who had disseminated tuberculosis that became manifest in the postpartum state. Wher...Miliary tuberculosis; Postpartum1995
100 Normann, Richard A.; Horch, Kenneth W.; Cha, KichulMobility performance with a pixelized vision systemA visual prosthesis, based on electrical stimulation of the visual cortex, has been suggested as a means for partially restoring functional vision in the blind. The prosthesis would create a pixelized visual sense consisting of punctate spots of light (phosphenes). The present study investigated the...Visual Prosthesis; Mobility; Phosphene Simulator1992
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