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CreatorTitleDescriptionSubjectDate
76 Couldwell, William T.Tunneled lumbar drainThe authors report a simple and rapid procedure for tunneling a lumbar drain subcutaneously to facilitate chronic cerebrospinal fluid (CSF) drainage. A standard lumbar puncture (LP) is performed with a large-bore Tuohy needle (14- to 16-gauge), the drainage catheter is advanced into the subarachnoid...Lumbar drain; Fistula2002
77 Couldwell, William T.Comment on Nugent, G. R.: Targeting the ventral lateral nucleus of the thalamus: a stereotactic vignetteDr. Nugent provides a fascinating personal account of his early experience with stereotactic surgery for movement disorders. I was especially pleased to read the positive comments regarding the personal interactions with and innovations of Irving Cooper, a neurosurgeon who was derided by his peers b...Stereotactic surgery; Stereotaxis2006
78 Couldwell, William T.Effect of absorbable topical hemostatic agents on the relaxation time of blood: an in vitro study with implications for postoperative magnetic resonance imagingAbsorbable topical hemostatic agents are commonly used in neurosurgery. In this study the authors examine the longitudinal relaxation time (T1) of blood in contact with these agents over time, measured in vitro, to determine if their presence could affect the interpretation of postoperative magneti...Absorbable hemostatic agent; Collastat; Surgicel; Oxidized regenerated cellulose; Methemoglobin2001
79 Couldwell, William T.Stress and burnout: insidious influencesA career in neurosurgery may take a substantial toll on an individual?s body and mind. From the ?baptism by fire? experienced by a brand-new junior resident, to keeping one?s head above water as the residency proceeds, to the realization shortly after graduation of being responsible for the health a...2008-01-01
80 Gluf, Wayne M.; Gottfried, Oren N.; Schmidt, Meic H.Cavernous hemangioma of the skull presenting with subdural hematomaCavernous hemangioma of the calvarium is a very rare disease, and patients usually present with headaches or a visible skull deformity. Few reports of patients presenting with intradiploic or epidural hemorrhages are found in the literature. No cases of an intradural hemorrhage from a cavernous hema...Hemangioma, Cavernous; Skull; Hematoma, Subdural2004-07-15
81 Couldwell, William T.Hemorrhagic and nonhemorrhagic Rathke cleft cysts mimicking pituitary apoplexyObject. Rathke cleft cysts (RCCs) are infrequently symptomatic, and apoplexy is one of the most unusual presentations. Only a few cases of apoplexy associated with RCCs have been reported, and their clinical, imaging, surgical, and pathological features are poorly understood. In the cases that have ...2008-01-01
82 Schmidt, Meic H.Cavernous hemangioma of the skull presenting with subdural hematomaCavernous hemangioma of the calvaria is a very rare disease, and patients usually present with headaches or a visible skull deformity. Few reports of patients presenting with intradiploic or epidural hemorrhages are found in the literature. No case of an intradural hemorrhage from a cavernous hemang...Calvaria; Cavernous hemangioma2004
83 Couldwell, William T.Harvey cushing and oskar hirsch: early forefathers of modern transsphenoidal surgeryThe transnasal transsphenoidal approach is the preferred route for removal of most lesions of the sella turcica. The concept of transnasal surgery traversing the sphenoid sinus to reach the sella has existed for nearly a century. A comprehensive historical overview of the evolution of transsphenoida...2005
84 Couldwell, William T.; Jensen, Randy L.; Jensen, Elizabeth M.Development of contrast enhancement after long-term observation of a dysembryoplastic neuroepithelial tumorDysembryoplastic neuroepithelial tumors (DNET) are usually benign lesions that arise in cortical regions and are discovered after new onset of seizure. These lesions have many different imaging characteristics. We report a patient with a presumed low-grade medial temporal lobe lesion that was follow...Brain tumor; Dysembryoplastic neuroepithelial tumors; DNET; Imaging; Seizures2006
85 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 16: bone graft extenders and substitutesStandards. The use of autologous bone or rhBMP-2 bone graft substitute is recommended in the setting of an ALIF in conjunction with a threaded titanium cage. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) Recombinant human BMP-2 in combination with HA ...Lumbar fusion; Lumbar spine; Bone graft; Treatment outcome; Practice guidelines; Degenerative disease2005
86 Couldwell, William T.Comment on Kitano, M., et al.: Subdural patch graft technique for watertight closure of large dural defects in extended transsphenoidal surgeryAhn and Kim demonstrate a suturing technique to close dural defects after transsphenoidal and extended transsphenoidal approaches. The technique entails a specifically designed forceps to cinch the knot down in the depths of the field. The Author's used the technique in 21 consecutive patients (16 e...Transsphenoidal surgery; CSF leaks2009
87 Kestle, John R. W.Comparison between magnetic resonance imaging and computed tomography for stereotactic coordinate determinationThe spatial accuracy of magnetic resonance imaging (MRI) has not been established for stereotactic surgery. Magnetic susceptibility artifacts may lead to anatomical distortion and inaccurate stereotactic MRI coordinates, especially when targets are in regions of the brain out of the center of the ma...Computed tomography; Stereotactic coordinates; Stereotactic surgery1992
88 Kestle, John R. W.; Walker, Marion L.Noncommunicating spinal extradural arachnoid cyst causing spinal cord compression in a childExtradural arachnoid cysts in the spine are relatively uncommon causes of spinal cord compression in the pediatric population that are thought to arise from congenital defects in the dura mater. Most reports describe such cysts communicating with the intrathecal subarachnoid space through a small de...2006
89 Dailey, Andrew T.Diagnosis and treatment of craniocervical dislocation in a series of 17 consecutive survivors during an 8-year periodObject. Craniocervical dissociation (CCD) is a highly unstable and usually fatal injury resulting from osseoligamentous disruption between the occiput and C-2. The purpose of this study was to elucidate systematic factors associated with delays in diagnosing and treating this life-threatening condit...Spinal cord injury; Craniocervical dislocation; Atlantooccipital joint; Atlantoaxial joint; Tetraplegia; CCJ; CCD2006
90 Schmidt, Meic H.Photodynamic therapyWe appreciate the comments of Drs. Kaye and Hill on our article. We are pleased that these investigators concurred with our impression that photodynamic therapy (PDT) may potentially be useful in the treatment of posterior fossa tumors. Several interesting questions were raised about the technical ...Photodynamic therapy; Photofrin1994
91 Couldwell, William T.Personal perspective: AANS Bulletin's momentum continues: new editor considers peer review, practice survey impactWith this issue, I assume the reins as editor of the AANS Bulletin. I am indebted to James Bean, MD, for his extraordinary efforts in this capacity, as witnessed by review of the recent issues published under his leadership. An important initiative put forth by Dr. Bean and the Bulletin Advisory Boa...2005
92 Couldwell, William T.Medical and surgical management of microprolactinomaA recent report by Colao et al. [1] indicates that a significant proportion of patients harboring prolactinomas treated with cabergoline will have persistence of remission of hyperprolactinemia following withdrawal of the drug. The prolactin and tumor control rates in the study suggest that medical ...Microprolactinoma; Prolactinoma; Cabergolene2004
93 Couldwell, William T.Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. a comparison between staurosporine and tamoxifenWE HAVE PREVIOUSLY demonstrated that the proliferation of established human glioma cell lines correlated with protein kinase C (PKC) activity and that a relatively selective PKC inhibitor, staurosporine, inhibits glioma cell proliferation. The purpose of this study was to determine whether low-passa...Staurosporin; Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Glioma cell lines1993
94 Schmidt, Meic H.; Brockmeyer, Douglas Lee; Dailey, Andrew T.Surgical management of aneurysmal bone cysts of the spineObject. Aneurysmal bone cysts of the spine are benign, highly vascular osseous lesions of unknown origin that may present difficult diagnostic and therapeutic challenges. They are expansile lesions containing thin-walled, blood-filled cystic cavities that cause bone destruction and sometimes spinal ...Aneurysmal bone cyst; Spine tumor; Spinal fusion; Embolization2003
95 Couldwell, William T.Metabolic syndrome: what neurosurgeons should knowThe term metabolic syndrome, first introduced in 1988, has evolved in concept since that time. While the strict definition is subject to ongoing debate, the syndrome generally involves glucose intolerance, obesity, dyslipidemia and high blood pressure, which increase the risk of developing cardiovas...2008-01-01
96 Schmidt, Meic H.Rod derotation techniques for thoracolumbar spinal deformityOBJECTIVE: The operative correction of scoliosis requires multiple intraoperative techniques and tools to achieve an adequate result. Frequently, multiple methods are used to accomplish this, such as rod cantilever techniques, in situ bending, Smith-Petersen and pedicle subtraction osteotomies, clo...2008-01-01
97 Kestle, John R. W.Predicting shunt failure on the basis of clinical symptoms and signs in childrenObject. In evaluating pediatric patients for shunt malfunction, predictive values for symptoms and signs are important in deciding which patients should undergo an imaging study, whereas determining clinical findings that correlate with a low probability of shunt failure could simplify management. ...Pediatric Shunt Design Trial; PSDT; Shunt failure; Shunt malfunction; Clinical signs2001
98 Couldwell, William T.Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase CTHE PROLIFERATION RATES of gliomas may be modulated by the protein kinase C (PKC) signal transduction system. The present study was undertaken to further examine the role of PKC system in growth regulation of gliomas in vitro by measurement of PKC activity over various phases of tumor growth and by ...Protein kinase C; Brain neoplasms; Growth factor; Glioma; Phorbol ester1992
99 Schmidt, Meic H.; Couldwell, William T.Far lateral transcondylar transtubercular approach to lesions of the ventral foramen magnum and craniovertebral junctionThe craniovertebral junction, which consists of the lower one third of the clivus, the foramen magnum, and the CI and C2 vertebrae, is a common site for neoplastic, vascular, congenital, and degenerative lesions of the cranial base. The far lateral transcondylar transtubercular approach (commonlyr...Far-lateral; Transcondylar; Transtubercular; Ventral foramen magnum; Craniovertebral junction2007
100 Schmidt, Meic H.Minimally invasive thoracoscopic approach for anterior decompression and stabilization of metastatic spine diseaseObject. The choices available in the management of metastatic spine disease are complex, and the role of surgical therapy is increasing. Recent studies have indicated that patients treated with direct surgical decompression and stabilization before radiation have better functional outcomes than thos...Metastatic spine disease; Minimally invasive surgery; Spinal cord decompression2008
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