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TitleDescriptionSubjectCollection
51 Keratin 7 staining in dysplastic epithelium of a bronchus (human, adult)Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). A red-brown staining with AEC indicates a positive reaction for cytokeratin 7. Disturbances in the growth and maturing might result in dysplasia of the epithelium with a changed reaction p...Immunoperoxidase; Immuno-reactionPoja Histology Collection - Respiratory System Subset
52 Keratin 7 staining in squamous metaplasia and dysplasia of the epithelium of a bronchus (human, adult)Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). A red-brown staining with AEC indicates a positive reaction for cytokeratin 7. Note that the top layer only reacts weakly positive for keratin 7 (↓). Upon squamous metaplasia the bronch...Squamous metaplasia; Immunoperoxidase; Immuno-reactionPoja Histology Collection - Respiratory System Subset
53 Keratin 7 staining in squamous metaplasia of the epithelium of a bronchiolus (human, adult)Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). A red-brown staining with AEC indicates a positive reaction for cytokeratin 7. Note that the top layer only is stained positively for keratin 7 (↓). Upon squamous metaplasia the bronchio...Bronchiolus; Squamous metaplasia; Immunoperoxidase; Immuno-reactionPoja Histology Collection - Respiratory System Subset
54 Keratin staining of bronchus epithelium (human, adult)Stain: Anti-keratin-5-7-14-19 (OVTL 12/5 monoclonal antibody with immunoperoxidase staining on frozen sections). The pseudostratified epithelium (1) is stained keratin-positively (brown product) as well as the epithelial derivates such as the bronchial glands (2) and their excretory ducts (3). Other...Bronchial epithelium; Keratin antibodies; Tumor diagnosisPoja Histology Collection - Respiratory System Subset
55 Keratin staining of bronchus epithelium (human, adult)Stain: Anti-keratin-5-7-14-19 (OVTL 12/5 monoclonal antibody with immunoperoxidase staining on frozen sedctions). The pseudostratified epithelium (1) reacts positively (brown-red product), the nuclei of the basal cells are well visible (arrows). Other structures react negatively (blue stain) such as...Tumor diagnosis; Bronchial epithelium; Lung parenchym; Keratin antibodiesPoja Histology Collection - Respiratory System Subset
56 Lamellar body of a type II alveolar cell in the lung (dog)Electron microscopy. Extrusion of surfactant material out of a type II alveolar cell (pneumocyte II, great alveolar cell). After fusion of a multilamellar body (1) (cytosome) with the apical cell membrane (note microvilli 2) the electron-dense lamellar content or surfactant (consisting of phosphatid...Type II alveolar cell; Pneumocyte II; Multilamellar bodies; Cytosomes; Tubular myelinPoja Histology Collection - Respiratory System Subset
57 Laminin in the canalicular period of the lung (mouse, embryo)Stain: Fluorescence microscopy with anti-laminin antibody. Laminin is a component of the basement membrane. Strong fluorescence visualizes the course of all basement membranes, especially around the bronchioles (B) and their branches in the developing lung tissue. In between the distal air spaces (t...Bronchioli; Canalicular periodPoja Histology Collection - Respiratory System Subset
58 Late terminal sac period of developing lung (human, fetus, low magnification)Stain: Hematoxylin and eosin. Cross-sections of a bronchus (1) with cartilage rings (2) closely associated with pulmonary arteries (3). The alveolar appearance is evident, and the open spaces represent future alveolar duct systems as well as alveolar sacs. The cellular septa are still thick due to n...Lung development; Terminal sac periodPoja Histology Collection - Respiratory System Subset
59 Longitudinal section of trachea (human, adult)Stain: Azan. On top: the epithelium (1) is pseudostratified with cilia and goblet cells. The dense lamina propria (2, ↓, deep blue) is demarcated from the submucosa with seromucous tracheal glands (3). C-shaped cartilage rings (C, light blue) maintain patency. The cartilage edges are connected by ...Pseudostratified epithelium ; Seromucous glands; Tracheal glands; Fibroelastic membrane ; AdventitiaPoja Histology Collection - Respiratory System Subset
60 Longitudinal section of trachea (human, adult)Stain: Azan. On top: the epithelium (1) is pseudostratified with cilia and goblet cells on a distinct basement membrane (↓). There is almost no demarcation (at this magnification) between lamina propria and submucosa due to the dense blue (2) staining of elastic fibers reinforced by collagen fiber...Pseudostratified epithelium ; Tracheal glands; Fibroelastic membranePoja Histology Collection - Respiratory System Subset
61 Lung alveoli (human)Stain: Azan. Alveoli (diameter about 200 m) are formed by thin walls of epithelial cells (1) such as type I alveolar cells and (blue stained) fine collagen (3) and elastin intermingled with dilated capillaries (2).Poja Histology Collection - Respiratory System Subset
62 Lung capillaries and air-blood barrier (rat)Electron microscopy. Two neighboring capillaries (C) and the alveolar spaces (A). The endothelial cell (1) of the upper capillary contains an organelle-rich cytoplasm, a centriole (2), contractile filaments (↓) and electron-dense membrane-bound granules, the so-called Weibel-Palade bodies. These b...Poja Histology Collection - Respiratory System Subset
63 Multilamellar bodies of type II alveolar cell in the lung (mouse)Electron microscopy. The cytoplasm of the type II alveolar cell (pneumocyte II) contains characteristic electron-dense multilamellar bodies (*) in different maturing stages. The lamellar bodies are responsible for the vacuolated appearance of these cells, and they give rise to surfactant (phospholip...Pneumocyte II; Multilamellar bodies; Type II alveolar cellPoja Histology Collection - Respiratory System Subset
64 Nasal concha (dog, isolated turbinate bone)Stain: Hematoxylin and eosin. This concha (turbinate with red-black-stained bone (1), is covered by a thin respiratory mucosa (3) and by a thick olfactory mucosa (2, arrow). Within the respiratory epithelium light stained goblet cells are visible between the low columnar/cuboidal epithelial cells (c...Conchae nasales; Olfactory epithelium; Respiratory epitheliumPoja Histology Collection - Respiratory System Subset
65 Nasal concha with respiratory mucosa (dog, high magnification)Stain: Hematoxylin and eosin. (↑) Indicates the transition of the olfactory epithelium (1) into the respiratory epithelium (2) with pseudostratified ciliated epithelium and goblet cells. The submucosa is richly vascularized (3). Lamellar bone of the turbinate (4) is stained reddish-black.Conchae nasales; Olfactory epithelium; Respiratory epitheliumPoja Histology Collection - Respiratory System Subset
66 Nasal glands of the nasal vestibulum (rat)Electron microscopy. At the top part of a striated draining duct with a wide lumen (*); these cuboidal ductal cells (1) contain many basolaterally located mitochondria. The ductal cells are enforced by interstitial fibroblast (2) and a capillary (4). Neighboring serous gland cells (5) contain dark s...Nasal vestibulum; Seromucous glands; Nasal glands; Serous cells; Secretion granules; Intercalated duct; Striated ductPoja Histology Collection - Respiratory System Subset
67 Nasal glands of the nasal vestibulum (rat)Electron microscopy. A low-power magnification reveals serous acini of a seromucous gland; in the center and lower left corner lumina (*) of the acini are present and dense secretion granules of varying sizes represent the active cells. Between the acini the distended interstitium reveals a fibrobla...Nasal vestibulum; Seromucous glands; Nasal glands; Serous cells; Secretion granulesPoja Histology Collection - Respiratory System Subset
68 Nasal glands of the nasal vestibulum (rat, higher magnification)Electron microscopy. Part of a serous acinus of a seromucous nasal gland demonstrates the central lumen (*) formed by four gland cells. Note junctional complexes (↑) and the close proximity of the dense secretion granules (2) ready to be released into the central lumen. These active cells contain ...Nasal vestibulum; Seromucous glands; Nasal glands; Serous cells; Secretion granulesPoja Histology Collection - Respiratory System Subset
69 Neuroepithelial body in terminal bronchiolus (golden hamster)Electron microscopy. Three epithelial cells, as part of the N(euro) E(pithelial) B(ody), contribute to a cluster of neuroendocrine cells. They belong to the Amine Precursor Uptake and Decarboxylation cell system so-called APUD cells. The dense-core granules (↓) contain among others dopamine or ser...Terminal bronchiolus ; Neuro-endocrine cellsPoja Histology Collection - Respiratory System Subset
70 Nostril area of nasal vestibulum - cutaneous region - humanStain: Azan. Slightly keratinized squamous epithelium (1) with thin red cornified layer; (2) hair follicles; (3) vibrissae and (4) associated sebaceous glands. At the bottom skeletal muscle fibers; (5) transverse part of the musculous nasalis; (6) connective tissue.Poja Histology Collection - Respiratory System Subset
71 Olfactory epithelium in the nasal cavity (mammals)Scheme electron microscopy. Four olfactory bulbs (1, vesicles) with radially sprouting cilia are present at the surface of the epithelium. Their slender cell bodies (2, bipolar neurons) are flanked by sustentacular (supporting) broad cells (3) whose apices are filled with well developed organelles, ...Pseudostratified epithelium; Olfactory epithelium; Basal cells; Olfactory vesicle; Bipolar neuronPoja Histology Collection - Respiratory System Subset
72 Olfactory epithelium in the nasal cavity (mammals)Three-dimensional scheme electron microscopy. Six olfactory cells (1) surround one massive central supporting cell (2). A third, basal cell (3) is located at the basal plate aposing to the supporting cell. These olfactory cells are tall and slender bipolar nerve cells with chemoreceptive functions. ...Pseudostratified epithelium; Olfactory epithelium; Basal cells; Olfactory vesicle; Bipolar neuronPoja Histology Collection - Respiratory System Subset
73 Olfactory epithelium in the nose (human)Electron microscopy. At the top (lumen) cross-sections of olfactory bulbs (1) (vesicles) with cilia/basal bodies. Sustentacular (supporting) cells (2) exhibit numerous microvilli in the lumen, their cytoplasms contain many dispersed mitochondria and in the lower half aggregations of endoplasmic reti...Olfactory epithelium; Olfactory vesiclePoja Histology Collection - Respiratory System Subset
74 Olfactory gland (Bowman) in olfactory region of concha (human)Electron microscopy. Beneath the olfactory epithelium tubuloalveolar glands of Bowman (1) are found containing cells that produce dense secretion granules arranged around a large lumen (*) with greyish secretion product. These cells produce a serous fluid in which odoriferous substances are dissolve...Olfactory epithelium; Bowman glands; Olfactory glands; Secretion granulesPoja Histology Collection - Respiratory System Subset
75 Olfactory mucosa in the nose (dog)Stain: Iron Hematoxylin and eosin (Heidenhain). The pseudostratified epithelium of the olfactory mucosa contains sensory cells, support cells and basal cells. The upper darker stained nuclei (1) belong to the supporting (sustentacular) cells showing a dark apical line (↑) at the top. Below lighte...Bowman glands; Olfactory glands; Olfactory mucosa; Pseudostratified epitheliumPoja Histology Collection - Respiratory System Subset
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