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51 Couldwell, William T.; House, Paul A.De novo fenestration of the optic nerveFenestration of the optic nerve or chiasm due to the presence of an aneurysmal dilation of the internal carotid artery (ICA) has been described previously. In three of five cases reviewed recently, the optic nerve was penetrated by an ICA?ophthalmic artery aneurysm.3 Penetration of the optic nerve w...Fenestration; Aneurysm2005
52 House, Paul A.; Couldwell, William T.De novo fenestration of the optic nerve case illustration.Fenestration of the optic nerve or chiasm due to the presence of aneurismal dilation of the internal carotid artery (ICA) has been described. In three out of five cases reviewed recently, the optic nerve was penetrated by an ICAΓÇôophthalmic artery aneurysm.3 Penetration of the optic nerve was du...Aneurysm; Congenital Optic Nerve2005-02-01
53 Kestle, John R. W.Death after late failure of third ventriculostomy in childrenLate failure following successful third ventriculostomy for obstructive hydrocephalus is rare, and death caused by failure of a previously successful third ventriculostomy has been reported only once. The authors present three patients who died as a result of increased intracranial pressure (ICP) a...Ventriculostomy; Obstructive hydrocephalus; Late failure; Death2002
54 Couldwell, William T.; Apfelbaum, Ronald I.Decompression of cavernous sinus meningioma for preservation and improvement of cranial nerve functionMeningiomas are the most common tumors affecting the cavernous sinus (CS). Despite advances in microsurgery and radiosurgery, treatment of CS meningiomas remains difficult and controversial. As in cases of other meningiomas, the goal of treatment for CS meningioma is long-term growth control and pre...2006-07
55 Couldwell, William T.Defining postoperative values for successful resection of prolactinomasWe, as other authors, have noted that late relapse of hyperprolactinemia following apparent successful adenomectomy in women harboring microprolactinomas is not rare.[1-3] On retrospective review of a series of tumors treated at the University of Southern California teaching hospitals, we have foun...Hyperprolactinemia; Microadenoma; Prolactin1996
56 Couldwell, William T.Definition of the role of contemporary surgical management in cisternal and parenchymatous cysticercosis cerebriWith increasing immigration from endemic regions, the incidence of neurocysticercosis in North America is rising. This retrospective study was undertaken to examine the role of surgery in those cases presenting with large cystic parenchymal and cisternal lesions in the current era of anthelminthic a...Brain cyst; Computed tomography; Neurocysticercosis; Magnetic resonance imaging; Praziquantel; Stereotaxis1991
57 Couldwell, William T.Delayed vasospasm after removal of a skull base meningiomaCerebral vasospasm is a well-known clinical entity associated with subarachnoid hemorrhage and traumatic brain injury [1,2]. In rare instances, vasospasm has been reported to occur after tumor resections, more specifically, after skull base tumor removal [3-5]. We report a rare case of a patient pre...2012-01-01
58 Kestle, John R. W.Determining the best cerebrospinal fluid shunt valve design: the pediatric valve design trialMyriad cerebrospinal fluid shunt valve designs are available (17, IS). None has ever been shown to be superior to another, although claims by neurosurgeons and shunt manufacturers of the merits of particular designs are numerous. Such is the case with two recent shunt valve designs, the Orbis-Sigm...Pediatric valve design; Shunt valves1996
59 Couldwell, William T.; Jensen, Randy L.; Jensen, Elizabeth M.Development of contrast enhancement after long-term observation of a dysembryoplastic neuroepithelial tumorDysembryoplastic neuroepithelial tumors (DNET) are usually benign lesions that arise in cortical regions and are discovered after new onset of seizure. These lesions have many different imaging characteristics. We report a patient with a presumed low-grade medial temporal lobe lesion that was follow...Brain tumor; Dysembryoplastic neuroepithelial tumors; DNET; Imaging; Seizures2006
60 Couldwell, William T.Development of neurosurgery in Southern California and the Los Angeles County/University of Southern California Medical CenterThe Los Angeles County General Hospital has played an integral role in the development of medicine and neurosurgery in Southern California. From its fledgling beginnings, the University of Southern California School of Medicine has been closely affiliated with the hospital, providing the predomina...Historical vignette; Los Angeles County General Hospital; University of Southern California School of Medicine; Neurosurgical history1993
61 Couldwell, William T.Diagnosis and management of Cushing diseaseThe management of a case involving Cushing disease, defined as excess secretion of adrenocorticotropic hormone (ACTH) from a pituitary adenoma, remains one of the most vexing problems facing the pituitary surgeon. The systemic consequences of this endocrinopathy are profound morbidity and premature...2007-01-01
62 Schmidt, Meic H.Diagnosis and management of sacral Tarlov cystsPerineurial (Tarlov) cysts are meningeal dilations of the posterior spinal nerve root sheath that most often affect sacral roots and can cause a progressive painful radiculopathy. Tarlov cysts are most commonly diagnosed by lumbosacral magnetic resonance imaging and can often be demonstrated by com...Tarlov cysts; Meningeal dilations; Spinal lesion; Outcome2003
63 Dailey, Andrew T.Diagnosis and treatment of craniocervical dislocation in a series of 17 consecutive survivors during an 8-year periodObject. Craniocervical dissociation (CCD) is a highly unstable and usually fatal injury resulting from osseoligamentous disruption between the occiput and C-2. The purpose of this study was to elucidate systematic factors associated with delays in diagnosing and treating this life-threatening condit...Spinal cord injury; Craniocervical dislocation; Atlantooccipital joint; Atlantoaxial joint; Tetraplegia; CCJ; CCD2006
64 Dailey, Andrew T.; Brodke, Darrel S.Differences between neurosurgeons and orthopaedic surgeons in classifying cervical dislocation injuries and making assessment and treatment decisions: a multicenter reliability studyVariability exists in the management of cervical spinal injuries. The goal of this study was to assess the effect of training specialty (orthopedic surgery vs neurosurgery) on management of cervical dislocations.Cervical dislocation injuries; Classification; Orthopedic surgeons; Orthopaedic surgeons; Assessment decisions; Treatment decisions2008
65 Schmidt, Meic H.Diffuse large B-cell lymphoma presenting as a sacral tumorPrimary lymphomas of the sacrum are rare tumors, reported only in a few cases in the literature. The authors describe two patients with diffuse large B-cell lymphomas presenting as a sacral tumor. In the first case a 52-year-old man presented with progressive back pain, bilateral radicular pain, an...B-cell lymphoma; Sacral tumor2003
66 Couldwell, William T.Distal ventriculoperitoneal shunt failure secondary to Clostridium Difficile ColitisDistal ventriculoperitoneal shunt obstruction is typically associated with cerebrospinal fluid (CSF) infection, fluid pseudocysts, bowel obstruction, bowel perforation, or improper shunt placement in the abdomen. We describe a unique etiology for distal shunt obstruction secondary to Clostridium dif...Shunt Failure2005-03
67 Couldwell, William T.; Gottfried, Oren N.Distal ventriculoperitoneal shunt failure secondary to clostridium difficile colitisDistal ventriculoperitoneal shunt obstruction is typically associated with cerebrospinal fluid (CSF) infection, fluid pseudocysts, bowel obstruction, bowel perforation, or improper shunt placement in the abdomen. We describe a unique etiology for distal shunt obstruction secondary to Clostridium di...2005-01-01
68 Kestle, John R. W.Does thalamotomy alter the course of Parkinson's disease?Irving Cooper (3) observed that unilateral Parkinson's disease seemed less likely to progress to the other side of the body after thalamotomy that abolished contralateral tremor and rigidity, an effect that he felt might be the result of either the surgery itself or the slow progression of that par...1996
69 Dailey, Andrew T.; Brodke, Darrel S.Dynamic cervical plates: biomechanical evaluation of load sharing and stiffnessStudy Design. An in vitro biomechanical study using a simulated cervical corpectomy model to compare the load-sharing properties and stiffnesses of two static and two dynamic cervical plates. Objectives. To evaluate the load-sharing properties of the instrumentation with a full-length graft and...In vitro biomechanical study; Cervical corpectomy; Cervical plates2001
70 Digre, Kathleen B.; Blumenthal, Deborah T.; Salzman, Karen L.; Jensen, Randy L.; Dunson, William A.Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis.A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-assoc...Paraneoplastic neurologic disorders; Encephalitis; Neoplasm;Herpes Simplex2006-07-11
71 Digre, Kathleen B.; Blumenthal, Deborah T.; Salzman, Karen L.; Jensen, Randy L.; Dunson, William A.Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis.A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-assoc...Paraneoplastic neurologic disorders; Encephalitis; Neoplasm;Herpes Simplex2006-07-11
72 Couldwell, William T.Effect of absorbable topical hemostatic agents on the relaxation time of blood: an in vitro study with implications for postoperative magnetic resonance imagingAbsorbable topical hemostatic agents are commonly used in neurosurgery. In this study the authors examine the longitudinal relaxation time (T1) of blood in contact with these agents over time, measured in vitro, to determine if their presence could affect the interpretation of postoperative magneti...Absorbable hemostatic agent; Collastat; Surgicel; Oxidized regenerated cellulose; Methemoglobin2001
73 Kestle, John R. W.Effect of hyperventilation on regional cerebral blood flow in head-injured childrenObjectives: To study cerebral blood flow and cerebral oxygen consumption in severe head-injured children and also to assess the effect of hyperventilation on regional cerebral blood flow. Design: Prospective cohort study. Setting: Pediatric intensive care unit at a tertiary-level university childre...Cerebral blood flow; Head injury; Jugular venous oximetry; Xenon computed tomography scan; Head-injured children1997
74 Kestle, John R. W.Effect of single-application topical ophthalmic anesthesia in patients with trigeminal neuralgia: a randomized double-blind placebo-controlled trialTo evaluate the reported benefit of ipsilateral single-application ophthalmic anesthetic eyedrops in patients with typical trigeminal neuralgia, a randomized double-blind placebo-controlled trial was performed. Fortyseven patients were randomly assigned to receive two drops of either proparacaine (...Randomized trial; Ophthalmic anesthesia1994
75 Couldwell, William T.Efficacy of clip-wrapping in treatment of complex pediatric aneurysmsPurpose: Pediatric aneurysms (PAs) are distinct from their adult counterparts with respect to typical location, aneurysm type, and known predisposing risk factors. Many strategies have been employed to treat PAs, but, although it has been used frequently in adults, clip-wrapping in pediatric patient...2012-01-01
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