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Creator | Title | Description | Subject | Date |
| 26 |
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Hawkes, Kristen | Human actuarial aging increases faster when background death rates are lower: a consequence of differential heterogeneity? | Many analyses of human populations have found that age-specific mortality rates increase faster across most of adulthood when overall mortality levels decline. This contradicts the relationship often expected from Williams' classic hypothesis about the effects of natural selection on the evolution o... | Frailty; Gompertz; Mortality rate doubling times; Ricklefs' omega; Strehler-Mildvan correlations; Weibull | 2011-01-01 |
| 27 |
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Gerig, Guido | Hypothesis testing with nonlinear shape models | We present a method for two-sample hypothesis testing for statistical shape analysis using nonlinear shape models. Our approach uses a true multivariate permutation test that is invariant to the scale of different model parameters and that explicitly accounts for the dependencies between variables. ... | | 2005-01-01 |
| 28 |
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Hawkes, Kristen | Increased longevity evolves from grandmothering | Postmenopausal longevity may have evolved in our lineage when ancestral grandmothers subsidized their daughters' fertility by provisioning grandchildren, but the verbal hypothesis has lacked mathematical support until now. Here, we present a formal simulation in which life spans similar to those of ... | Human evolution; Life history; Sexual conflict | 2012-01-01 |
| 29 |
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Hawkes, Kristen | Kin selection and culture | This paper argues that while the discriminations organizing human action are cultural, and kinship in anthropology is not equivalent to genetic relatedness, the theory of kin selection developed in evolutionary biology can tell us a great deal about human social organization. Data on garden assistan... | | 1983-01-01 |
| 30 |
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Hawkes, Kristen | Mortality and fertility rates in humans and chimpanzees: how within-species variation complicates cross-species comparisons | A grandmother hypothesis may explain why humans evolved greater longevity while continuing to end female fertility at about the same age as do the other great apes. With that grandmother hypothesis in mind, we sought to compare age-specific mortality and fertility rates between humans and chimpanzee... | | 2009-01-01 |
| 31 |
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Gerig, Guido | Network inefficiencies in autism spectrum disorder at 24 months | Autism spectrum disorder (ASD) is a developmental disorder defined by behavioral symptoms that emerge during the first years of life. Associated with these symptoms are differences in the structure of a wide array of brain regions, and in the connectivity between these regions. However, the use of c... | | 2014-01-01 |
| 32 |
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North American Neuro-Ophthalmology Society (NANOS) | Neuro-ophthalmology virtual education library (NOVEL) | An extensive, accessible collection of high quality digital materials to cover all of neuro-ophthalmology for use by educators and students world wide. | Neuro-Ophthalmology; NOVEL; Neuro-Ophthalmology Virtual Education Library | 2005-08-11 |
| 33 |
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Gerig, Guido | Neuroimaging of structural pathology and connectomics in traumatic brain injury: toward personalized outcome prediction | Recent contributions to the body of knowledge on traumatic brain injury (TBI) favor the view that multimodal neuroimaging using structural and functionalmagnetic resonance imaging (MRI and fMRI, respectively) as well as diffusion tensor imaging (DTI) has excellent potential to identify novel biomark... | Trauma; Neuroimaging; MRI/fMRI; Diffusion tensor; Outcome measures | 2012-01-01 |
| 34 |
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Gerig, Guido | Object models in multiscale intrinsic coordinates via m-reps | Object descriptions used for 3D segmentation by deformable models and for statistical characterization of 3D object classes benefit from having intrinsic correspondences over deformation of the objects or multiple instances in the same object class. These correspondences apply over a variety of spat... | | 2003-01-01 |
| 35 |
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Hawkes, Kristen | Ovarian follicle loss in humans and mice: lessons from statistical model comparison | Menopause is triggered by the number of ovarian follicles falling below a threshold number and is irreversible because oogonial stem cells disappear after birth. Since it is the result of programmed disappearance of a limited store of follicles, menopause can be predicted using mathematical models b... | Age; Follice; Mathematical; Model; Menopause; Ovary | 2010-01-01 |
| 36 |
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Gerig, Guido | Particle based shape regression of open surfaces with applications to developmental neuroimaging | Shape regression promises to be an important tool to study the relationship between anatomy and underlying clinical or biological parameters, such as age. In this paper we propose a new method to building shape models that incorporates regression analysis in the process of optimizing correspondences... | | 2009-01-01 |
| 37 |
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Gerig, Guido | Prenatal isolated mild ventriculomegaly is associated with persistent ventricle enlargement at ages 1 and 2 | Background-Enlargement of the lateral ventricles is thought to originate from abnormal prenatal brain development and is associated with neurodevelopmental disorders. Fetal isolated mild ventriculomegaly (MVM) is associated with enlargement of lateral ventricle volumes in the neonatal period and dev... | Magnetic resonance imaging; Ultrasound; Gray matter; White matter; Cognitive development | 2012-01-01 |
| 38 |
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Gerig, Guido | Probabilistic fiber tracking using particle filtering | This paper presents a novel and fast probabilistic method for white matter fiber tracking from diffusion weighted MRI (DWI). We formulate fiber tracking on a nonlinear state space model which is able to capture both smoothness regularity of fibers and uncertainties of the local fiber orientations du... | | 2007-01-01 |
| 39 |
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Gerig, Guido | Probabilistic white matter fiber tracking using, particle filtering and von mises-fisher sampling | Standard particle filtering technique have previously been applied to the problem of fiber tracking by Brun et al. (2002) and Bjornemo et al. (2002). However, these previous attempts have not utilised the full power of the technique, and as a result the fiber paths were tracked in a goal directed wa... | Diffusion tensor MRI; Tractography; Probabilistic fiber tracking; Particle filtering; von Mises-Fisher sampling | 2009-01-01 |
| 40 |
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Gerig, Guido | Quantification of measurement error in DTI: theoretical predictions and validation | The presence of Rician noise in magnetic resonance imaging (MRI) introduces systematic errors in diffusion tensor imaging (DTI) measurements. This paper evaluates gradient direction schemes and tensor estimation routines to determine how to achieve the maximum accuracy and precision of tensor derive... | | 2007-01-01 |
| 41 |
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Gerig, Guido | Quantitative tract-based white matter development from birth to age 2 years | Few large-scale studies have been done to characterize the normal human brain white matter growth in the first years of life. We investigated white matter maturation patterns in major fiber pathways in a large cohort of healthy young children from birth to age two using diffusion parameters fraction... | White matter maturation; Axonal myelination; Early brain development; Diffusion properties; DTI atlas; Fiber tracking; Functional regression analysis | 2012-01-01 |
| 42 |
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Gerig, Guido | Reduced interhemispheric connectivity in schizophrenia- tractography based segmentation of the corpus callosum | Background-A reduction in interhemispheric connectivity is thought to contribute to the etiology of schizophrenia. Diffusion Tensor Imaging (DTI) measures the diffusion of water and can be used to describe the integrity of the corpus callosum white matter tracts, thereby providing information concer... | | 2008-01-01 |
| 43 |
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Gerig, Guido | Simulation of brain tumors in MR images for evaluation of segmentation efficacy. | Obtaining validation data and comparison metrics for segmentation of magnetic resonance images (MRI) are difficult tasks due to the lack of reliable ground truth. This problem is even more evident for images presenting pathology, which can both alter tissue appearance through infiltration and cause ... | Brain MRI; Segmentation validation; Tumor simulation; Simulation of tumor infiltration; Diffusion tensor imaging; Ground truth; Gold standard | 2009-01-01 |
| 44 |
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Gerig, Guido | Spatiotemporal atlas estimation for developmental delay detection in longitudinal datasets | We propose a new methodology to analyze the anatomical variability of a set of longitudinal data (population scanned at several ages). This method accounts not only for the usual 3D anatomical variability (geometry of structures), but also for possible changes in the dynamics of evolution of the str... | | 2009-01-01 |
| 45 |
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Gerig, Guido | Unbiased atlas formation via large deformations metric mapping | The construction of population atlases is a key issue in medical image analysis, and particularly in brain mapping. Large sets of images are mapped into a common coordinate system to study intrapopulation variability and inter-population differences, to provide voxelwise mapping of functional sites,... | Computational anatomy; Brain atlases; Image metric space | 2005-01-01 |
| 46 |
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Gerig, Guido | User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability | Active contour segmentation and its robust implementation using level set methods are well-established theoretical approaches that have been studied thoroughly in the image analysis literature. Despite the existence of these powerful segmentation methods, the needs of clinical research continue to b... | Computational anatomy; Image segmentation; Caudate nucleus; 3D active contour models; Open source software; Validation; Anatomical objects | 2006-01-01 |
| 47 |
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Gerton, Jordan | Using a sharp metal tip to control the polarization and direction of emission from a quantum dot | Optical antennas can be used to manipulate the direction and polarization of radiation from an emitter. Usually, these metallic nanostructures utilize localized plasmon resonances to generate highly directional and strongly polarized emission, which is determined predominantly by the antenna geometr... | | 2014-01-01 |
| 48 |
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Gerig, Guido | Vessel tortuosity and brain tumor malignancy: a blinded study | Rationale-Malignancy provokes regional changes to vessel shape. Characteristic vessel tortuosity abnormalities appear early during tumor development, affect initially healthy vessels, spread beyond the confines of tumor margins, and do not simply mirror tissue perfusion. The ability to detect and qu... | Computer; Cancer; Blood vessels; Tortuosity; MRA; Brain tumor | 2005-01-01 |
