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TitleDescriptionSubjectCollection
276 Lymphoblast (spleen, rat)Electron microscopy. Interspersed between small lymphocytes the lymphoblast with a high nucleus-cytoplasm ratio is a larger cell with a distinct nucleolus. The cytoplasm is studded with numerous polysomes and ribosomes, only few mitochondria and a single strand of rough endoplasmic reticulum are pre...Poja Histology Collection - Blood & Bone Marrow Subset
277 Lymphoblast in splenic cord of red pulp (rat)Electron microscopy. A free circulating more matured lymphoblast with a conspicuous nucleus and nucleolus (1) still contains many polysomes (2), the swollen mitochondria (3) are obvious. A single fat droplet (4) and Golgi vesicles (5) are present. The cell is partly surrounded by reticular cell exte...electron microscopy; lymphoblastPoja Histology Collection - Lymphatic Tissues and Organs Subset
278 Lymphoblast in splenic white pulp (rat, human)Electron microscopy (A, rat) and Methyl green (B, human). Upon antigenic stimulation the lymphocytes in the germinal centre proliferate and generate activated B cells or lymphoblasts which seed towards marginal zone and red pulp while differentiating. Due to the increased number of lymphoblasts, ret...electron microscopy; lymphoblastPoja Histology Collection - Lymphatic Tissues and Organs Subset
279 LymphocyteScheme electron microscopy. A lymphocyte with an indented nucleus and (1) nucleolus shows a juxta-nuclear Golgi area (2) and centriole (3), several mitochondria (4) and sparsely profiles of rough endoplasmic reticulum (5) in the cytoplasm. Few dense-stained granules (6) are present. The granules con...Poja Histology Collection - Blood & Bone Marrow Subset
280 Lymphocyte (mature)Scheme electron microscopy. Mature B and T lymphocytes are ameboid cells (5-8 m) with a high nucleus-cytoplasmic ratio. The cytoplasm contains a juxta-nuclear Golgi area (1) with centrioles (2), few large mitochondria (3) and sparsely profiles of rough endoplasmic reticulum (4) are present. The surf...Poja Histology Collection - Blood & Bone Marrow Subset
281 Lymphocyte (mature) (peripheral blood, human)Electron microscopy. Mature B and T lymphocytes are ameboid cells (5-8 m) with a high nucleus-cytoplasmic ratio. The cytoplasm contains a juxta-nuclear Golgi area with centrioles (6), few large mitochondria (4). Profiles of rough endoplasmic reticulum (RER) (5) are sparsely present. The surface exhi...Poja Histology Collection - Blood & Bone Marrow Subset
282 Lymphocyte (peripheral blood, human)Electron microscopy. (Cytotoxic) lymphocyte (A) with a juxta-nuclear Golgi area (3) and centrioles (2), few mitochondria (4) and sparsely profiles of rough endoplasmic reticulum (RER). Dense-stained granules (1) are present. The surface exhibits short blunt microvilli. The right lymphocyte in (B) ha...Poja Histology Collection - Blood & Bone Marrow Subset
283 MHC-class II dendritic cells in spleen (rat)Stain: Immunohistochemistry of Vector red staining of MHC-class II with ER13 antibody. The survey in (A) shows that MHC-class II expressing cells are conspicuously concentrated in dendritic cell types (B) in the transition zone between red pulp (2) and white pulp (1). These dendritic or antigen-pres...MHC class II; dendritic cells; immunofluorescencePoja Histology Collection - Lymphatic Tissues and Organs Subset
284 Macrophage-sheathed capillaries in spleen (human)Azan. The branching of each penicillar arteriole gives rise to capillaries and a slow-down of the blood stream. In certain regions monocyte-derived macrophages leave the capillary and enter its wall where they develop into macrophages. Together with the present reticular cells these cell accumulatio...macrophage-sheathed capillaries; penicillar arterioles; sinusoidPoja Histology Collection - Lymphatic Tissues and Organs Subset
285 Macroscopy of fetus (human)The fetus (1)is completely wrapped in a shiny transparent amnion (2) and closely associated with the brown-coloured placenta (3). (By courtesy of the Museum of Anatomy and Pathology, University Medical Center, St. Radboud University, Nijmegen, The Netherlands)fetus; placenta; amnionPoja Histology Collection - Placenta
286 Mast cellMast cells (mastocytes) are oval (12 m) or spindle-shaped and are frequently found perivascularly or perineurally. The cytoplasm is provided with a moderate amount of organelles and small thin or blunt microvilli at the surface. Most obvious is the presence of large granules varying in shape and siz...Poja Histology Collection - Blood & Bone Marrow Subset
287 Mast cell (connective tissue, human)Electron microscopy. Mast cells (mastocytes) are frequently found perivascularly or perineurally within the connective tissue. A detail of this mast cell shows granules varying in shape and size. These membrane-bound vesicles (so-called compound granules) show a metachromatic reaction in light micro...Poja Histology Collection - Blood & Bone Marrow Subset
288 Mast cell (lung, dog)Electron microscopy. This mucosal mast cell of the lung is localized in the vicinity of a blood vessel. Notice the smooth muscle cells (1) of a small arteriole and collagen fibers (2). Most obvious is the presence of granules varying in shape and size. These membrane-bound vesicles (so-called compou...Poja Histology Collection - Blood & Bone Marrow Subset
289 Mast cell (lung, golden hamster)Electron microscopy. Mucosa mast cells (mastocytes) are frequently found perivascularly or perineurally. The mast cell shows long thin microvilli at the surface and the cytoplasm is stuffed with granules (1) varying in shape and size. At (2) a Golgi area and at (3) small mitochondria and some electr...Poja Histology Collection - Blood & Bone Marrow Subset
290 Mast cell (lung, human)Electron microscopy. Mast cells (mastocytes) are oval (12 m) or spindle-shaped and show few thin microvilli at the surface. They are frequently found perivascularly or perineurally within the connective tissue (1). The cytoplasm is provided with a moderate amount of organelles. Most obvious is the p...Poja Histology Collection - Blood & Bone Marrow Subset
291 Mast cell (lung, human)Electron microscopy. Mast cells (mastocytes) are frequently found perivascularly or perineurally. A part of this mast cell shows thin microvilli at the surface and the cytoplasm is provided with a moderate amount of organelles. At (*) the Golgi area (1) is seen in close association with granules tha...Poja Histology Collection - Blood & Bone Marrow Subset
292 Mast cell in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). The mast cell (1) is characterized by the presence of coarse purple-black granules and a nucleus with oval, central nucleus. The granules contain pharmacologically active mediators such as heparin, histamine, neutrophil- and eosinophil-chemotactic factors, vasoactive...Poja Histology Collection - Blood & Bone Marrow Subset
293 Mast cells in peripheral blood smear (human)Stain: May-Grnwald-Giemsa (MGG). Mast cells (1) from two different smears. (2) Monocyte. Mast cells or tissue basophils are normally present in small numbers in bone marrow smears. They must not be confused with developing basophils. Mast cells are large cells (20-30 m in diameter) with an irregular...Poja Histology Collection - Blood & Bone Marrow Subset
294 Maturation stages of plasmablasts (spleen, liver rat)Electron microscopy. The youngest (plasmacytoid) lymphocyte in (A) shows a slight indented nucleus with a distinct nucleolus. Apart from a few mitochondria the cytoplasm contains large amount of free ribosomes and polysomes, few profiles of long rough endoplasmic reticulum (1, RER) and Golgi areas (...Poja Histology Collection - Blood & Bone Marrow Subset
295 Mature erythrocytes (spleen, gerbil)Scanning electron microscopy. Normal mature erythrocytes (1) are mostly biconcave and discoid. They might change their forms due to mechanical pressures. (2) a mature lymphocyte recognizable by many short stubby microvilli at the surface. (3) granulocytes are larger with fewer but longer microvilli....Poja Histology Collection - Blood & Bone Marrow Subset
296 Medulla of lymph node (human)Stain: Azan. Part of the medulla showing medullary cords (1) and medullary sinuses (2) close to the hilum and capsule (3). The medullary cords consist of a meshwork of reticular fibers and reticular cells (blue-stained). The cords (1) are more stuffed with lymphocytes and other blood cells. The sinu...medullar cords; medullar sinus; hilumPoja Histology Collection - Lymphatic Tissues and Organs Subset
297 Medulla of thymus (human, puberty)Stain: Hematoxylin. The light-stained medulla consists of a loosened framework of epithelial reticular cells, macrophages, thymocytes and capillaries. Accumulations of a specialized type of epithelial reticular cells (1) are localized between the thymocytes. These clusters represent precursors of fu...thymic corpuscle (Hassalls); epithelioreticular cell (ERC); thymus medulla; lymphoid tissuePoja Histology Collection - Lymphatic Tissues and Organs Subset
298 Medullary cords and sinus in lymph node (mouse)Stain: Trichrome (Goldner). Detail of medullary sinus (1) flanked by part of medullar cords (2). The sinus space (1) is lined by flattened littoral cells (foamed cytoplasm) (?) and dispersedly filled with lymphocytes (4) and macrophages (brown hemo-pigment) (3). Within the medullary cords one finds ...medullar cords; medullar sinusPoja Histology Collection - Lymphatic Tissues and Organs Subset
299 Medullary part of lymph node (human)Stain: Azan. Part of the medulla with darkly stained medullary cords (1) and lightly stained medullary sinuses (2). The cords are stuffed with densely packed lymphocytes and reticular cells. Their blue-stained structures indicate massive bundles of reticular fibres. The sinuses are lined by flattene...medulla; medullar cords; sinusPoja Histology Collection - Lymphatic Tissues and Organs Subset
300 Megakaryoblast in bone marrow smear (human)Stain: May-Grnwald-Giemsa (MGG). The megakaryoblast (1) is not yet producing platelets and has a relative small amount of basophilic cytoplasm. The nucleus is large with fine disperse chromatin and nucleoli. Most other nucleated cells are of the myeloid cell line.Poja Histology Collection - Blood & Bone Marrow Subset
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