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276 Couldwell, William T.Review by Oren N. Gottfried, M.D. and William T. Couldwell, M.D., Ph.D for Neurosurgery Journal Club. (Yadav JS, Wholey MH, Kuntz RE, et al: Protected carotid-artery stenting versus endarterectomy in high-risk patients.)This is an important study that helps further define a role for carotid stenting as a therapeutic option for atherosclerotic carotid disease. There is a need for a larger-scale multi-centered trial with increased numbers patients and longer follow-up to identify appropriate patients for either endar...Carotid Stenosis; Endarterectomy, Carotid; Stents2005-01-07
277 Jaeckle, Kurt A.; Digre, Kathleen B.; Jones, Christopher R.; Bailey, Peter L.Central neurogenic hyperventilation: pharmacologic intervention with morphine sulfate and correlative analysis of respiratory, sleep, and ocular motor dysfunction.Central neurogenic hyperventilation (CNH), for which there is no effective therapy, can eventually result in respiratory fatigue and death. This report describes a patient with CNH due to a brainstem anaplastic astrocytoma who also exhibited disturbances of sleep and ocular motor function. The CNH r...Central Neurogenic H yperventilation; Ocular Motor Dysfunction1990-11
278 Couldwell, William T.Posterolateral approach for decompression with anterior and posterior fusion: a less invasive surgical technique for stabilization of the thoracic spineThe goals of surgery in unstable thoracic fractures or tumors involving the thoracic spine are neural decompression, correction of deformity, and stabilization. Several different approaches can be used to achieve these goals. The anterior, combined anterior and posterior, and more recently thoraco...Decompression; Thoracic spine; Posterolateral approach1998
279 Couldwell, William T.Prognostic variables in surgery for skull base meningiomasThe authors have retrospectively analyzed selected surgical and pathological observations made among a group of 20 patients harboring recurrent cranial base meningiomas in an attempt to reveal which factors may be important in predicting tumor recurrence. This cohort was compared with a group of 3...Skull base; Prognostic factor; Recurrence1997
280 Schmidt, Meic H.Cervical spine deformity associated with resection of spinal cord tumorsPostoperative sagittal-plane cervical spine deformities are a concern when laminectomy is performed for tumor resection in the spinal cord. These deformities appear to occur more commonly after resection of intramedullary spinal cord lesions, compared with laminectomy for stenosis caused by degener...Kyphosis; Cervical deformity; Intramedullary tumor; Laminectomy; Children2006
281 Couldwell, William T.Surgical approaches to petroclival meningiomas part I: upper and midclival approachesStrictly considered, petroclival meningiomas represent only a percentage of the 10% of all intracranial meningiomas that reside in the posterior fossa. Although not statistically frequent, with their location in proximity to cranial nerves, the basilar artery and its perforating branches, and t...Petroclival meningiomas; Petroclivus; Surgical approach; Upper clivus; Midclivus1994
282 Kestle, John R. W.Determining the best cerebrospinal fluid shunt valve design: the pediatric valve design trialMyriad cerebrospinal fluid shunt valve designs are available (17, IS). None has ever been shown to be superior to another, although claims by neurosurgeons and shunt manufacturers of the merits of particular designs are numerous. Such is the case with two recent shunt valve designs, the Orbis-Sigm...Pediatric valve design; Shunt valves1996
283 Dailey, Andrew T.Pathophysiology of oral pharyngeal apraxia and mutism following posterior fossa tumor resection in childrenMutism following posterior fossa tumor resection in pediatric patients has been previously recognized, although its pathophysiology remains unclear. A review of the available literature reveals 33 individuals with this condition, with only a few adults documented in the population. All of these pati...Vermis; Posterior fossa tumor; Pediatric patients1995
284 Kestle, John R. W.Response to editorial: summer shuntingWe thank Dr. Scott for his review and comments about our report of shunt surgery complications in the summer. He makes two very good points. Clearly, different databases are suited for different purposes, and the NIS database used in the study by Smith and colleagues is well suited to evaluating t...2006
285 Couldwell, William T.; Apfelbaum, Ronald I.Variations on the standard transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches: surgical experience in 105 casesThe traditional boundaries of the transsphenoidal approach may be expanded to include the region from the cribriform plate of the anterior cranial base to the inferior clivus in the anteroposterior plane, and laterally to expose the cavernous cranial nerves and the optic canal. We review our combin...Transsphenoidal surgery; Chordoma; Craniopharyngioma; Intracranial neoplasm; Meningioma; Pituitary adenoma; Sella turcica; Transsphenoidal craniotomy2004
286 Kestle, John R. W.Reduction of hemorrhage risk after stereotactic radiosurgery for cavernous malformationsThe benefits of radiosurgery for cavernous malformations are difficult to assess because of the unclear natural history of this vascular lesion, the inability to image malformation vessels, and the lack of an imaging technique that defines "cure." The authors selected for radiosurgery 47 patients w...Cavernous malformation; Gamma knife; Stereotactic radiosurgery1995
287 Couldwell, William T.Role of CCM1 loss-of-function-induced endothelial-to-mesenchymal transition in the development of cavernous malformationsCerebral cavernous malformations (CCM) occur in two variants: sporadic and familial. Mutations in three genes-CCM1, CCM2, and CCM3-play a role in both subtypes, with mouse models showing the development of multiple cavernous malformations in animals with loss of function in any of these three genes....2013-01-01
288 Couldwell, William T.Pituitary modelsPituitary tumor animal models provide researchers a microenvironment that simulates the clinical situation; however, in comparison with astrocytoma and meningioma tumor research where intracranial xenograft transplantations are increasingly being used to test various therapeutic modalities, in vivo ...2013-01-01
289 Kestle, John R. W.Abdominal bindersSklar and colleagues2 describe their experience managing "over-shunting headaches" with an abdominal binder. Seventy children with over-shunting headaches complied with application of a binder for about 1 month. In 61 patients (87%), the headaches "greatly improved or went away." This headache relie...2012-01-01
290 Schmidt, Meic H.Spinal extradural arachnoid cysts: clinical, radiological, and surgical featuresExtradural arachnoid cysts in the spine are rare and are seldom a cause of spinal cord compression. They are thought to arise from congenital defects in the dura mater, and they almost always communicate with the intrathecal subarachnoid space through a small defect in the dura. The mainstay of trea...Spinal extradural arachnoid cyst; Spinal meningeal cyst; Neurogenic claudication2007
291 Schmidt, Meic H.Minimally invasive thoracoscopic resection of paraspinal neurogenic tumors: technical case reportOBJECTIVE: The posterior mediastinum is a common location for benign neurogenic tumors. They are frequently asymptomatic but can present with local compressive or neurological symptoms. METHODS: Thoracoscopy is used increasingly over posterolateral thoracotomy for the removal of these lesions. RES...2008-01-01
292 Couldwell, William T.; Schmidt, Richard H.Ruptured intracranial dermoid cysts: clinical, radiographic, and surgical featuresIntracranial dermoid cysts are pathologically characterized by a thick, stratified squamous epithelium cyst wall containing dermal elements. Rupture into the subarachnoid spaces and ventricles is extremely rare. We review the clinical, radiographic, and surgical features of eight ruptured dermoid c...Dermoid cyst; Intracranial; Rupture; Tumor2008
293 Couldwell, William T.; MacDonald, Joel D.Revision of vagal nerve stimulator electrodes: technical approachPurpose To demonstrate the feasibility of complete removal of the vagal nerve stimulator electrode using microsurgical technique. Methods Operative databases at the University of Utah (1995 through 2002), Westchester Medical Center (1995 through 2001), and University of Arizona Health Sciences Ce...Vagal nerve stimulation; Helical electrode; Electrode revision2004
294 Dailey, Andrew T.; Moore, Kevin R.Value of MR neurography for evaluating extraspinal neuropathic leg pain: a pictorial essaySummary: Fifteen patients with neuropathic leg pain referable to the lumbosacral plexus or sciatic nerve underwent high-resolution MR neurography. Thirteen of the patients also underwent routine MR imaging of the lumbar segments of the spinal cord before undergoing MR neurography. Using phased-array...MR neurography; Neuropathic leg pain; Extraspinal; Lumbosacral plexus2001
295 Couldwell, William T.Defining postoperative values for successful resection of prolactinomasWe, as other authors, have noted that late relapse of hyperprolactinemia following apparent successful adenomectomy in women harboring microprolactinomas is not rare.[1-3] On retrospective review of a series of tumors treated at the University of Southern California teaching hospitals, we have foun...Hyperprolactinemia; Microadenoma; Prolactin1996
296 Couldwell, William T.Resolution of an anterior-inferior cerebellar artery feeding aneurysm with the treatment of a transverse-sigmoid dural arteriovenous fistulaThe authors describe a 27-year old man who developed an unruptured anterior-inferior cerebellar artery feeding aneurysm from a transverse-sigmoid dAVF and its subsequent resolution with the treatment of the dAVF. The patient, with a known history of left transverse and sigmoid sinus thrombosis, pres...Aneurysms; Dural Arteriovenous Fistulas; Endovascular therapy; Surgery2007
297 Schmidt, Meic H.; MacDonald, Joel D.; Jensen, Randy L.; Couldwell, William T.Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinusStereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary,...Hypophysial transposition; Hypophysopexy; Pituitary tumors; Stereotactic radiosurgery; Pituitary transposition; Hypopituitarism2003
298 Couldwell, William T.Ventroposterior medial pallidotomy in patients with advanced Parkinson's diseaseIN A PRELIMINARY study, the effects of ventroposterior medial pallidotomy were evaluated in five patients with advanced Parkinson's disease in whom medical therapy had failed. The mean age was 67.0 ? 5.6 years, and t h e mean Hoelin and Yahr stage when "off" was 3.9 ? 1.3. Three patients received u...Pallidotomy; Dyskinesia; Stereotaxy; Postoperative morbidity1995
299 Schmidt, Meic H.; Apfelbaum, Ronald I.Chylorrhea: a rare complication of thoracoscopic discectomy of the thoracolumbar junctionThe thoracic duct along with the cisterna chyli is a major lymphatic pathway near the anterior thoracolumbar spine. Despite the fragile nature of the lymphatic system and its proximity to the spinal column, chylorrhea is rarely encountered by spine surgeons. The authors present a unique case of chyl...Chylous leak; Thoracoscopy; Thoracic spine; Thoracoscopic discectomy; Thoracolumbar junction; Chylorrhea2007
300 Schmidt, Meic H.Medical applications of space light-emitting diode technology-space station and beyondSpace light-emitting diode (LED) technology has provided medicine with a new tool capable of delivering light deep into tissues of the body, at wavelengths which are biologically optimal for cancer treatment and wound healing. This LED technology has already flown on Space Shuttle missions, and show...Photodynamic therapy; Lutetium Texaphyrin; Lutex; Canine glioma1999
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