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226 Keratin 7 staining in squamous metaplasia of the epithelium of a bronchiolus (human, adult)Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). A red-brown staining with AEC indicates a positive reaction for cytokeratin 7. Note that the top layer only is stained positively for keratin 7 (↓). Upon squamous metaplasia the bronchio...Bronchiolus; Squamous metaplasia; Immunoperoxidase; Immuno-reactionPoja Histology Collection - Respiratory System Subset
227 The alveolar tip in lung tissue (human, adult)Electron microscopy. The lung tip is covered by a flattened alveolar cell type I (↓1) and a similar neighboring bulging one with nucleus (2). In the alveolar tip amorph elastin (5) appears more electron-dense than the collagen fibers (Col) and is interwoven with it. Small foci of calcifications a...Alveolar tip; ElastoblastPoja Histology Collection - Respiratory System Subset
228 Alveolar cell type II (pneumocyte II) in an alveolus (dog)Electron microscopy. At (X) the alveolar space, the bulging alveolar cell type II shows the characteristic multilamellar bodies (*, cytosomes) that contain precusor material of surfactant. The lamellar bodies are responsible for the vacuolated appearance of these cells, and they give rise to surfact...Pneumocyte II; Alveolar cell type IIPoja Histology Collection - Respiratory System Subset
229 Olfactory vesicle (bulb) in the nose (gerbil)Electron microscopy. A distinct olfactory bulb (1, vesicle) with horizontally extended cross-sectioned cilia (*) and basal bodies (↑) is surrounded by numerous microvilli and free olfactory cilia. Close to the first bulb a second one is about to protrude above the surface of the supporting cells b...Olfactory epithelium; Olfactory vesiclePoja Histology Collection - Respiratory System Subset
230 Survey of bronchus and lung parenchym (human, adult)Stain: Azan. (1) Lumen of small bronchus beside a lumen of pulmonary artery (2). Thin plates of hyaline cartilage (3) and connective tissue surrounding (1) and (2). Arrows (→) indicate lung alveoli with black-stained patches of carbon deposits. (4) Lung parenchym with alveoli.Lung parenchymPoja Histology Collection - Respiratory System Subset
231 Bronchiolus in the lung (human, adult)Stain: Azan. The lumen is lined with one layer of ciliated epithelium (1) without goblet cells. Patches of smooth muscle fibers (2) are present. Notice small bronchial arteries (*). Arrows (↓) indicate sites of carbon accumulations between the alveoli (3).Bronchiolus; Ciliated epitheliumPoja Histology Collection - Respiratory System Subset
232 Respiratory epithelium in the nasal vestibulum (rat)Scanning electron microscopy. Note bushes of cilia (1) on the ciliary epithelium. In between areas of short microvilli-studded bulging or flattened goblet cells. Remnants of erythrocytes (2) are also found on top of ciliated cells.Respiratory epithelium; Nasal vestibulumPoja Histology Collection - Respiratory System Subset
233 Survey of lung parenchym (gerbil)Scanning electron microscopy. The photograph shows (1) bifurcation of several bronchi in the lung parenchym with alveoli (2). The long arrows indicate the route of alveolar ducts (4 ↕ length, and cross 4↑). Pulmonary vessels (3).Lung parenchym; Pulmonary vesselsPoja Histology Collection - Respiratory System Subset
234 Surface of trachea epithelium (rat)Scanning electronmicroscopy. There is an abundancy of cilia with interspersed protrusions (↓) of goblet cells due to apical secretion.Pseudostratified epitheliumPoja Histology Collection - Respiratory System Subset
235 Choriocarcinoma (human)Stain: Hematoxylin-eosin. (A) Inset: Survey tumor. Within the uterus (1) a choriocarcinoma forms solitary or multiple nodules composed of hemorrhagic necrotic areas (2) surrounded by neoplastic cells. It resembles an early implanted blastocyst with aggregations of mononuclear lighter-stained cyt...choriocarcinoma; placenta; uterus; cytotrophoblast; GTD (gestational trophoblastic disease)Poja Histology Collection - Placenta
236 Epithelial lining of terminal bronchiolus (golden hamster)Electron microscopy (low magnification). Two major epithelial cell types line the bronchiolus: (1) the ciliated cells with many organelles, and (2) the non-ciliated cells or Clara cells well provided with organelles, especially agranular endoplasmic reticulum and depending on their activity, numerou...Terminal bronchiolus; Ciliated epithelium ; Clara cells; Neuro-endocrine cells; Pneumocytes; Alveolar cell types; InterstitiumPoja Histology Collection - Respiratory System Subset
237 Electron microscopy of tertiary villus (human placenta, midpregnancy)In the left photograph (A) is shown part of a tertiary villus with the organelle-rich cytoplasm of a syncytiotrophoblast cell (STC, 1). Below a single electron-light linked cytotrophoblast cell (CTC or Langhans cell, 2) covered by the STC. A higher magnification of another CTC (right photograph) sh...placenta; tertiary villi; syncytiotrophoblast; electron microscopy; placental barrierPoja Histology Collection - Placenta
238 Normal term placenta with umbilical cord attached to the fetus (human)The macroscopy shows the expelled placenta as a discoidal mass with a circular outline about 15-20 cm in the ruptured amnionitic and chorionic sacs. Amnion and smooth chorion (chorion leave) are fused and continuous with the margins of the placenta. The fetal surface (inner surface) is covered by...placenta; amnion; chorion; umbilical cord; fetusPoja Histology Collection - Placenta
239 Survey of the intervillous space with villi (human placenta, full-term)Stain: Perjodic Acid Schiff reaction (PAS). At the right and left side the chorionic plate (1) with few cross-sectioned umbilical vessels (2), at (3) a detached amnion. Cross-sections of thick stem villi (4) at the fetal side ramify into terminal villi (tertiary) that are found stuffed (due to fix...placenta; stem villus; syncytiotrophoblast; amnionPoja Histology Collection - Placenta
240 Brush cell in lung (rat)Electron microscopy. In the proximal as well as in the terminal airways a special type of cell can be observed, the so-called brush (-border) cell. In this picture this cell is located in the alveolar space. At (1) the brush border of thick plump microvilli. In the cytoplasm a Gogi area, mitochondri...Brush cellPoja Histology Collection - Respiratory System Subset
241 Survey of the nasal conchae (dog, isolated turbinate bones)Stain: Hematoxylin and eosin. The conchae (turbinates) consist of three parts: the inferior, middle and superior turbinate bones (3, black-stained); they are covered by a respiratory mucosa (1) or by an olfactory mucosa (2). In humans only a small part of the superior concha exhibits olfactory epith...Conchae nasales; Olfactory epithelium; Respiratory epitheliumPoja Histology Collection - Respiratory System Subset
242 Transitional zone in the middle part of nasal vestibulum (comparable with red zone or vermilion border of lip, human)Stain: Azan. At the right slightly cornified squamous epithelium (1) with small dermal papillae (2) and numerous blood vessels (3). To the left the transition to pseudostratified epithelium (4). In the submucosa branching seromucous nasal glands with draining ducts (5).Stratified epithelium; Pseudostratified epithelium; Nasal glands; Seromucous glandsPoja Histology Collection - Respiratory System Subset
243 Survey of bronchus and lung parenchym (human, adult)Stain: Azan. Lumina of bifurcated bronchi (1, 2). Thin plates of hyaline cartilage (3) and connective tissue surround the bronchi. Arrows (→) indicate lung alveoli with black-stained patches of carbon deposits. (4) Lung parenchyma with alveoli.Lung parenchymPoja Histology Collection - Respiratory System Subset
244 Chorioamnionitis (human)Histologically chorioamnionitis describes the progression of the inflammatory process. Bacteria firstly colonized the chorioamniotic surface. In first two days polymorphonuclear granulocytes (PMN) migrate to the chorion (chorionitis) marginate and adhere to the bottom of the chorionic plate (stage 1...chorioamnionitis; placenta; trophoblastPoja Histology Collection - Placenta
245 Partial hydatidiform mole and invasive mole (human)(A) Macroscopy: The partial mole (1) occupies a large part of the placenta and is distinct from the normal chorionic plate where the umbilical cord (2) inserts eccentrically with branches of the umbilical vessels. The inset shows a circumscript area with swollen transparent grape-like vesicles (chor...partial hydatidiform mole ; chorioadenomaPoja Histology Collection - Placenta
246 Immunohistochemistry of thymus (rat)Stain: Alexa-594 red immunofluorescence. (1) Medulla. (2) Cortex. (A): Staining with a monoclonal antibody against vimentin illustrates that vimentin is localised in the stromal cells of the connective tissue of the capsule, of the septa or trabeculae that invade the cortex (2) and overwhelmingly ...vimentin; laminin; fibronectin; ED2 monoclonal antibodyPoja Histology Collection - Lymphatic Tissues and Organs Subset
247 Lymph node (human)Stain: Azan. Left and right: survey of lymph nodes, compare the individual differences between the nodes. The pictures display the cortex (1) with capsule (3), and the medulla (2). The cortex consists of (secondary) follicles displaying a clear germinal centre (4). The paracortex (T cell area) is ...follicle; paracortex; cortex; germinal centerPoja Histology Collection - Lymphatic Tissues and Organs Subset
248 Normal term placenta (human)(A) Left (fetal surface): 30-90 cm long umbilical cord (1), remnant of ruptured transparent amnion (2→) , near the eccentric attachment of the umbilical cord to the chorion plate ramification of the umbilical vessels (3) (arteries are smaller than the veins). (B) Right (maternal surface). The su...placenta; amnion; chorion plate; cotyledonPoja Histology Collection - Placenta
249 Survey and detail of the chorionic plate and intervillous space (human placenta, full-term)Stain: (A) Perjodic acid-Schiff reaction (PAS); (B) Hematoxylin-azophloxine. (A) At the top the chorionic plate (1) with cross-sections of umbilical vessels (2). At (3) the folded amnion covering the chorionic plate. Ramifications of thicker stem villi (6) demonstrate free-floating terminal villi ...placenta; chorionic plate; amnion; terminal villiPoja Histology Collection - Placenta
250 Spleen with central artery in secondary lymphatic nodule (human)Stain: Azan. The white pulp consists of (1) a cross-section of the central artery, (2) the germinal centre with few branches of the central artery; the mantle zone (3) and the marginal zone (4) surrounded by a perilymphoid zone around the nodule. The perilymphoid zone is composed of concentricall...germinal center; PALS; central artery; marginal zonePoja Histology Collection - Lymphatic Tissues and Organs Subset
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