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CreatorTitleDescriptionSubjectDate
226 Bernstein, Paul S.HPLC measurement of ocular carotenoid levels in human donor eyes in the lutein supplementation era.PURPOSE: A substantial proportion of the population at risk for visual loss from age-related macular degeneration consumes supplements containing high doses of lutein, but clinical studies to date have shown only modest and variable increases in macular carotenoid pigments in response to supplementa...Chromatography, High Pressure Liquid; Dietary Supplements; Tissue Donors2007-02
227 Olson, Randall J.Comparison of patient satisfaction after uncomplicated cataract surgery between the silicone AMO SI-30/40 and the acrylic Alcon MA30BA and MA60BA foldable intraocular lensesPURPOSE: To compare patient satisfaction with vision 12 months after implantation of a silicone or acrylic foldable intraocular lens (IOL). SETTING: John A. Moran Eye Center, University of Utah Medical Center, Salt Lake City, Utah, USA. METHODS: Selection criteria included patients who had uneventfu...Patient Satisfaction; Lenses, Intraocular; Silicone Elastomers; Biocompatible Materials2001-10
228 Baehr, WolfgangIdentification and light-dependent translocation of a cone-specific antigen, (Cone Arrestin) recognized by monoclonal antibody 7G6PURPOSE: To elucidate the antigen recognized by monoclonal antibody (mAb) 7G6, a widely used cone-specific marker. METHODS: 7G6 immunocytochemistry was performed on sections of human, primate, and bovine retina. The antigen was immunoprecipitated from human retinal lysates and purified with protein ...Cones (Retina); Molecular Sequence Data; Phototransduction2003
229 Couldwell, William T.Predictive value of serum prolactin levels measured immediately after transsphenoidal surgeryObject. Prolactin-secreting pituitary adenomas may be managed by surgery, medication, radiotherapy, or observation. The authors reviewed a consecutive series of patients who were followed for at least 5 years after surgery to assess the prognostic significance of preoperative factors (tumor size and...Prolactin; Transsphenoidal surgery; Pituitary adenoma; Prolactinoma; Transsphenoidal approach2002
230 Pepper, Ginette A.Improving geriatric drug therapy.Healthcare professional and society in general harbor ambivalent beliefs about drug therapy. Most of us anticipate that drugs will eventually control, or even cure many age-related diseases. On the other hand, there is a growing unease about the hazards of medications, which range from minor discomf...Older people1987-10
231 Bernstein, Paul S.; Zabriskie, Norman A.; Zhang, Kang; Leppert, Mark F.Diverse macular dystrophy phenotype caused by a novel complex mutation in the ELOVL4 genePURPOSE: A 5-bp deletion in ELOVL4, a photoreceptor-specific gene, has been associated with autosomal dominant (ad) macular dystrophy phenotypes in five related families, in which phenotypes range from Stargardt-like macular dystrophy (STGD3; Mendelian Inheritance in Man 600110) to pattern dystrophy...Linkage (Genetics); Middle Older people; Phenotype2001
232 Foster, Norman L.Novel insertional presenilin 1 mutation causing Alzheimer disease with spastic paraparesis.A four-generation pedigree exhibiting early-onset autosomal dominant Alzheimer disease (AD) with spastic paraplegia, dystonia, and dysarthria due to a novel 6-nucleotide insertional mutation in exon 3 of the presenilin 1 gene (PS1) is described. Serial examinations, PET scans, and autopsy revealed t...Older people, 80 and over; Membrane Proteins; Neuropsychological Tests2004-05-25
233 Smith, A. Gordon; Singleton, J. RobinsonLifestyle intervention for pre-diabetic neuropathy.OBJECTIVE: The purpose of this study was to evaluate intraepidermal nerve fiber density (IENFD) as a sensitive measure of neuropathy change in patients with neuropathy associated with impaired glucose tolerance (IGT) receiving lifestyle intervention based on that used in the Diabetes Prevention Prog...Older people; Biopsy; Blood Pressure; Body Mass Index; Cholesterol; Diabetic Diet2006-06-29
234 Normann, Richard A.Acute human brain responses to intracortical microelectrode arrays: challenges and future prospectsThe emerging field of neuroprosthetics is focused on the development of new therapeutic interventions that will be able to restore some lost neural function by selective electrical stimulation or by harnessing activity recorded from populations of neurons. As more and more patients benefit from thes...2014-01-01
235 Light, Alan R.Activation of Src family kinases in spinal microglia contributes to formalin-induced persistent pain state through p38 pathwayProtein tyrosine phosphorylation has been implicated in normal and pathological functions, such as cell proliferation, migration and differentiation. Recently, some studies have shown that Src family kinases (SFKs) were involved in neurological disorders and neuropathic pain states in which microgli...2012-01-01
236 Normann, Richard A.Adaptive parameter selection for asynchronous intrafascicular multi-electrode stimulationThis paper describes an adaptive algorithm for selecting perelectrode stimulus intensities and inter-electrode stimulation phasing to achieve desired isometric plantar-flexion forces via asynchronous, intrafascicular multi-electrode stimulation. The algorithm employed a linear model of force product...2012-01-01
237 Narus, Scott P.Birth of identity: Understanding changes to birth certificates and their value for identity resolutionIntroduction Identity information is often used to link records within or among information systems in public health and clinical settings. The quality and stability of birth certificate identifiers impacts both the success of linkage efforts and the value of birth certificate registries for identit...2014-01-01
238 Reimherr, Frederick W.Neuropsychological functioning and OROS® methylphenidate in an Adult Attention-Deficit/Hyperactivity Disorder (ADHD) populationObjective: Neuropsychological tests have been used in attention-deficit/hyperactivity disorder (ADHD) to compare ADHD patients with normal subjects, to assess drug-placebo differences in clinical trials and to identify appropriate medication levels via test dose paradigms. While clinical studies h...Trapeze Interactive Poster2010-03-15
239 Kestle, John R. W.Effect of hyperventilation on regional cerebral blood flow in head-injured childrenObjectives: To study cerebral blood flow and cerebral oxygen consumption in severe head-injured children and also to assess the effect of hyperventilation on regional cerebral blood flow. Design: Prospective cohort study. Setting: Pediatric intensive care unit at a tertiary-level university childre...Cerebral blood flow; Head injury; Jugular venous oximetry; Xenon computed tomography scan; Head-injured children1997
240 Schmidt, Meic H.Role of thoracoscopic spinal surgery in the management of pyogenic vertebral osteomyelitisStudy Design. Case report, operative technique. Objectives. Vertebral osteomyelitis is frequently associated with elderly and debilitated patients who have significant medical comorbidities. If surgical debridement is contemplated, an open anterior approach like a thoracotomy can be associated with...Thoracoscopic spinal surgery; Pyogenic vertebral osteomyelitis2004
241 Digre, Kathleen B.; Blumenthal, Deborah T.; Cessna, Melissa H.; Gopez, Evelyn V.; Shen, YueCarcinomatous meningitis as the presenting manifestation of gallbladder carcinoma: case report and review of the literatureThe primary tumors that typically cause carcinomatous meningitis include lung cancer, breast cancer, leukemia, lymphoma and melanoma. A variety of neurological signs and symptoms can be seen depending on the extent and location of the meningeal metastasis. Once the diagnosis of carcinomatous meningi...Carcinomatous Meningitis; Gallbladder Carcinoma; Leptomeningeal Metastasis; Meningeal Carcinomatosis; Cranial Neuropathy2004-10
242 Schmidt, Meic H.Pigmented villonodular synovitis associated with pathological fracture of the odontoid and atlantoaxial instabilityPPigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovium with a predisposition for the appendicular skeleton. Rarely PVNS can arise from the spine, where this disorder usually presents with localized or radicular pain secondary to involvement of the posterior elements. Th...Atlantoaxial instability; Pigmented villonodular synovitis; Odontoid2007
243 Zhang, KangIdentification and functional consequences of a new mutation (E155G) in the gene for GCAP1 that causes autosomal dominant cone dystrophy2001
244 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 10: fusion following decompression in patients with stenosis without spondylolisthesisStandards. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) In situ posterolateral lumbar fusion is not recommended as a treatment option in patients with lumbar stenosis in whom there is n...Fusion; Lumbar spine; Degenerative disease; Lumbar fusion2005
245 Caserta, Michael; Lund, Dale A.Future directions in adult bereavement researchThe primary purpose of this article is to stimulate interest in conducting research related to adult bereavement and provide suggestions for improving the quality of these studies and the application of their findings. Future research needs to generate new knowledge about grief and bereavement but ...1998
246 Kestle, John R. W.Value of postoperative surveillance imaging in the management of children with some common brain tumorsThe rationale for obtaining surveillance computerized tomography (CT) scans or magnetic resonance (MR) images in pediatric patients with brain tumors is that early detection of recurrence may result in timely treatment and better outcome. The purpose of this study was to investigate the value of sur...Brain neoplasm; Brain tumors; Computerized tomography scanning; Surveillance; Postoperative surveillance1996
247 Couldwell, William T.; Gillespie, David L.Ubiquitous expression of cyclooxygenase-2 in meningiomas and decrease in cell growth following in vitro treatment with the inhibitor celecoxib: potential therapeutic applicationObject. Meningiomas are the second most common symptomatic primary central nervous system tumor in adults. Findings of epidemiological studies link meningiomas with a history of head trauma, indicating a causal relationship between the inflammatory response and meningioma tumorigenesis. Cyclooxygena...2005-09
248 Varner, Michael W.Human placental lactogen: a predictor of perinatal outcome?Serial human placental lactogen (hPL) determinations were performed on 806 women with normal and abnormal pregnancies late in the pregnancy. These results were not reported to the clinicians involved. For the study population as a whole, low hPL levels did not effectively predict those adverse perin...Infant, Newborn; Placental Lactogen; Pregnancy; Prenatal Diagnosis1979-08
249 Couldwell, William T.Man for all seasons: W.W. KeenWILLIAM WILLIAMS KEEN was the catalyst for the advent of neurosurgery in the United States. He served in the Civil War and collaborated with Silas Weir Mitchell in studying injuries sustained to the nervous system. These studies culminated in the publication in 1864 of Gunshot Wounds and Other Inj...Brain tumor2002
250 Thomas, Kirk R.; Capecchi, Mario R.Location of crossovers during gene targeting with insertion and replacement vectors.Gene targeting was used to introduce nonselectable genetic changes into chromosomal loci in mouse embryo-derived stem cells. The nonselectable markers were linked to a selectable marker in both insertion- and replacement-type vectors, and the transfer of the two elements to the Hprt locus was assaye...Genetic Vectors; Molecular Sequence Data; Restriction Mapping1993-04
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