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226 Schmidt, Meic H.Titanium cage-assisted polymethylmethacrylate reconstruction for cervical spinal metastasisReconstruction and stabilization of the cervical spine after vertebrectomy is an important goal in the surgical management of spinal metastasis. The authors describe their reconstruction technique using a titanium cage-Silastic tube construct injected with polymethylmethacrylate (PMMA) augmented by...Titanium cage; Cervical spine; Cervical spinal metastasis; Reconstruction; Vertebrectomy; PMMA reconstruction; Silastic tube2005
227 Couldwell, William T.Submandibular-infratemporal interpositional carotid artery bypass for cranial base tumors and giant aneurysmsCerebral revascularization is an important strategy in the surgical management of some complex cranial base tumors and unclippable aneurysms. A highflow bypass may be necessary in planned carotid occlusion or sacrifice. The cervical-to-supraclinoid internal carotid artery bypass or cervical carotid-...Internal carotid artery; Cranial base tumors; Giant aneurysms; Interpositional bypass; Surgical approach; Radial artery; Revascularization; Saphenous vein; Submandibular infratemporal bypass2006
228 Dailey, Andrew T.Vertebral artery injuries associated with cervical spine injuries: a review of the literatureObjective: To determine the incidence of vertebral artery injuries (VAIs) in association with cervical spine trauma and investigate the optimum diagnostic and treatment protocols. Summary of Background Data: VAIs may result from cervical spine trauma and have the potential to cause cerebral, brain...Cervical spine injuries; Literature review2008
229 Couldwell, William T.Irving S. Cooper (1922-1985): a pioneer in functional neurosurgeryIrving S. Cooper (1922-1985), the son of a salesman, worked his way through high school, college, and medical school to become one of the pioneers in functional neurosurgery. He developed several novel techniques for the surgical management of Parkinson's disease and other crippling movement disord...Functional neurosurgery; Cryosurgery; Dystonia; Movement disorder; Parkinson's disease; Thalamotomy; Tremor; Neurosurgical history1998
230 Couldwell, William T.Surgical approaches to petroclival meningiomas Part II: extended approachesIn Part I, the classification, clinical presentation, and upper and midclival surgical approaches were discussed. This lesson covers extended surgical approaches, results, complications, and adjuvant therapy.Petroclival meningiomas; Petroclivus; Surgical approach; Staged surgery; Complications; Adjuvant therapy; Radiosurgery; Resections1994
231 Couldwell, William T.Transmaxillary approach to the anterior cavernous sinus: a microanatomic studyOBJECTIVE: Several approaches to expose the anterior cavernous sinus have been used, such as frontotemporal, orbitofrontal, anterior subtemporal, and various transfacial approaches. In an effort to gain exposure to the anterior cavernous sinus without necessitating a craniotomy or wide transfacial ...Anterior cavernous sinus; Clivus; Cranial base; Maxillary sinus1997
232 Couldwell, William T.; Gottfried, Oren N.Surgical management of posterior petrous meningiomasPosterior petrous meningiomas (commonly termed posterior pyramid meningiomas and/or meningiomas of the posterior surface of the petrous pyramid) are the most common meningiomas of the posterior cranial fossa. They are located along the posterior surface of the temporal bone in the region of the cere...2003-01-01
233 Couldwell, William T.Resident curriculum guidelines for neurosurgeryThis curriculum was created to detail the body of knowledge that should be attained by an individual completing residency training in neurological surgery. The specific structure of resident education in neurological surgery is defined by the American Board of Neurological Surgery, and each program...Residency training; Neurological surgery2000
234 Couldwell, William T.Neurosurgical implications of allergic fungal sinusitisObject. Allergic fungal sinusitis (AFS) is a form of paranasal mycosis that often involves bone destruction and extension into the orbit and anterior skull base. Treatment consists of surgical extirpation and a course of corticosteroids. Despite frequent intracranial involvement, AFS is rarely repor...2004
235 Couldwell, William T.Comment on: Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trialsThe long-term consequences of adenovirus-mediated conditional cytotoxic gene therapy for gliomas remain uncharacterized. We report here detection of active brain inflammation 3 months after successful inhibition of syngeneic glioma growth. The inflammatory infiltrate consisted of activated macrophag...Brain inflammation; Herpes simplex virus-1; Thymidine kinase; Syngeneic glioma; Adenovirus-mediated gene therapy1994
236 Kestle, John R. W.Shunt insertion in the summer: is it safe?Object. The potential for increased complications related to the arrival of new residents in July each year has not previously been demonstrated in the neurosurgical literature. The authors investigated this phenomenon in children undergoing cerebrospinal fluid shunt surgery. Methods. Data were ob...Ventriculoperitoneal shunt; July effect; Complication; Shunt insertion2006
237 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 12: pedicle screw fixation as an adjunct to posterolateral fusion for low-back painStandard. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) Pedicle screw fixation is recommended as a treatment option for patients with low-back pain treated with PLF who are at high risk...Fusion procedures; Degenerative disease; Lumbar spine; Pedicle screw fixation; Posterolateral fusion; Low-back pain2005
238 Kestle, John R. W.; Brockmeyer, Douglas LeeEvaluation of the necessity of postoperative imaging after craniosynostosis surgeryObject. Childhood radiation exposure increases the lifetime risk of cancer from an estimated 0.07 to 0.35%. Neurological evaluation of patients after cranial vault reconstruction for synostosis repair is often complicated by pain medication, sedation, intubation, swelling, and dressings; therefore c...Computed tomography; Cranial vault reconstruction; Pediatric neurosurgery; Radiation dose; Postoperative imaging2007
239 Kestle, John R. W.; Walker, Marion L.Noncommunicating spinal extradural arachnoid cyst causing spinal cord compression in a childExtradural arachnoid cysts in the spine are relatively uncommon causes of spinal cord compression in the pediatric population that are thought to arise from congenital defects in the dura mater. Most reports describe such cysts communicating with the intrathecal subarachnoid space through a small de...2006
240 Dailey, Andrew T.Diagnosis and treatment of craniocervical dislocation in a series of 17 consecutive survivors during an 8-year periodObject. Craniocervical dissociation (CCD) is a highly unstable and usually fatal injury resulting from osseoligamentous disruption between the occiput and C-2. The purpose of this study was to elucidate systematic factors associated with delays in diagnosing and treating this life-threatening condit...Spinal cord injury; Craniocervical dislocation; Atlantooccipital joint; Atlantoaxial joint; Tetraplegia; CCJ; CCD2006
241 Schmidt, Meic H.Photodynamic therapyWe appreciate the comments of Drs. Kaye and Hill on our article. We are pleased that these investigators concurred with our impression that photodynamic therapy (PDT) may potentially be useful in the treatment of posterior fossa tumors. Several interesting questions were raised about the technical ...Photodynamic therapy; Photofrin1994
242 Kestle, John R. W.Priorities for hydrocephalus research: report from a National Institutes of Health-sponsored workshopObject. Treatment for hydrocephalus has not advanced appreciably since the advent of cerebrospinal fluid (CSF) shunts more than 50 years ago. Many questions remain that clinical and basic research could address, which in turn could improve therapeutic options. To clarify the main issues facing hydr...Biomedical research2007
243 Couldwell, William T.; Gillespie, David L.; Jensen, Randy L.Identification of hypoxia-induced genes in a malignant glioma cell line (U-251) by cDNA microarray analysisOvercoming the metabolic restrictions of hypoxia may allow the progression of lower-grade tumors to glioblastoma multiforme. Our findings of up-regulation of HIF-1α and its downstream targets VEGF, GLUT-1, and CAIX in higher-grade gliomas support this hypothesis. We compared the gene expression pro...Glioblastoma multiforme; U-251; Hypoxia; Microarray analysis; Brain tumor; Depp; Astrocytoma2007
244 Couldwell, William T.Response to comment on: the combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumorsWe appreciate the comments by Dr. Sanna regarding our article (1). We recognize Dr. Sanna has much experience with these tumors and that, as cranial base surgeons, we should work as a team of neurosurgeons, otologists, and occasionally, head and neck surgeons and plastic surgeons. We also agree tha...Jugular foramen tumor; Glomus jugulare tumors2007
245 Couldwell, William T.Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case reportLEVAMISOLE AND 5-FLUOROURACIL have now become the standard chemotherapeutic regimen for patients with Stage 111 colon carcinoma. A case of multifocal inflammatory leukoencephalopathy secondary to levamisole alone or combination of levamisole and 5-fluorouracil is reported. Magnetic resonance imaging...Autopsy; Levamisole; Multifocal inflammatory leukoencephalopathy1994
246 Couldwell, William T.Comparison of radiosurgery and conventional surgery for the treatment of glomus jugulare tumorsObject. The optimal management of glomus jugulare tumors remains controversial. Available treatments were once associated with poor outcomes and significant complication rates. Advances in skull base surgery and the delivery of radiation therapy by stereotactic radiosurgery have improved the results...2004
247 Couldwell, William T.Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitroDirect measurement of protein kinase C (PKC) activity in vitro revealed a significant increase in the activity of the enzyme in all human malignant glioma lines examined and the rat C6 tumor in comparison with control nonneoplastic astrocyte and mixed glial cultures. The total and particulate PKC ac...Brain neoplasms; Flow cytometry; Glioma; Phorbol ester; Protein kinase C1991
248 Dailey, Andrew T.; Schmidt, Meic H.; Apfelbaum, Ronald I.Anterior fixation of odontoid fractures in an elderly populationObject. Fractures of the odontoid process are the most common fractures of the cervical spine in patients over the age of 70 years. The incidence of fracture nonunion in this population has been estimated to be 20-fold greater than that in patients under the age of 50 years if surgical stabilizatio...Odontoid fractures; Elderly population; Anterior fixation2010
249 Couldwell, William T.Comment on Kitano, M. and Taneda, M.: Extended transsphenoidal approach to the anterior communicating artery aneurysm: aneurysm incidentally identified during macroadenoma resectionKitano and Taneda describe the successful clipping of an ACoA aneurysm via the transsphenoidal approach. There are limitations of the approach; most notable are the limited and narrow corridor and the relationship between the aneurysm and the optic chiasm, which may hinder full visualization of the ...Aneurysm; Transsphenoidal approach2007
250 Couldwell, William T.; House, Paul A.De novo fenestration of the optic nerveFenestration of the optic nerve or chiasm due to the presence of an aneurysmal dilation of the internal carotid artery (ICA) has been described previously. In three of five cases reviewed recently, the optic nerve was penetrated by an ICA?ophthalmic artery aneurysm.3 Penetration of the optic nerve w...Fenestration; Aneurysm2005
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