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Creator | Title | Description | Subject | Date |
| 226 |
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Couldwell, William T. | Photophobia in a blind patient: an alternate visual pathway | Photophobia is a common neurological and ophthalmological symptom that has been associated with a growing number of neurosurgical conditions, especially compressive lesions. The exact signaling pathways and neurophysiological features of the disorder are not well understood; however, data from mult... | | 2006-11 |
| 227 |
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Digre, Kathleen B.; Couldwell, William T.; Amini, Amin | Photophobia in a blind patient: An alternate visual pathway. Case report. | Photophobia is a common neurological and ophthalmological symptom that has been associated with a growing number of neurosurgical conditions, especially compressive lesions. The exact signaling pathways and neurophysiological features of the disorder are not well understood; however, data from multi... | Photophobia, Blindness, Signaling Pathway, Pretectal Nuclei, Trigeminal Pathway | 2006-12-14 |
| 228 |
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Schmidt, Meic H. | Pigmented villonodular synovitis associated with pathological fracture of the odontoid and atlantoaxial instability | PPigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovium with a predisposition for the appendicular skeleton. Rarely PVNS can arise from the spine, where this disorder usually presents with localized or radicular pain secondary to involvement of the posterior elements. Th... | Atlantoaxial instability; Pigmented villonodular synovitis; Odontoid | 2007 |
| 229 |
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Schmidt, Meic H.; Couldwell, William T. | Far lateral transcondylar transtubercular approach to lesions of the ventral foramen magnum and craniovertebral junction | The craniovertebral junction, which consists of the lower one third of the clivus, the foramen magnum, and the CI and C2 vertebrae, is a common site for neoplastic, vascular, congenital, and degenerative lesions of the cranial base. The far lateral transcondylar transtubercular approach (commonlyr... | Far-lateral; Transcondylar; Transtubercular; Ventral foramen magnum; Craniovertebral junction | 2007 |
| 230 |
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Kestle, John R. W.; Brockmeyer, Douglas Lee | Optic pathway gliomas: a review | Optic pathway gliomas represent approximately 3-5% of childhood intracranial tumors. They usually occur in children during the first decade of life and are seen in 11-30% of patients with neurofibromatosis Type 1 (NF1). Although these tumors are typically low-grade gliomas, the clinical course and n... | Optic pathway glioma; Hypothalamus glioma; Neurofibromatosis Type 1 | 2007 |
| 231 |
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Couldwell, William T.; Davidson, H. Christian | Trigeminal amyloidoma: case report and review of the literature | The authors present a case of amyloid infiltration involving the trigeminal nerve that mimicked a malignant cavernous sinus tumor with perineural tumor infiltration. A 64-year-old man presented with trigeminal nerve numbness. Imaging revealed a plaque-like enhancing lesion along the right lateral ca... | Gasserian ganglion; Trigeminal; Amyloidoma | 2007 |
| 232 |
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Kestle, John R. W. | Predicting slitlike ventricles in children on the basis of baseline characteristics at the time of shunt insertion | Object. Slit ventricle syndrome (SVS) is a delayed complication of shunt insertion and occurs only in children with slitlike ventricles after shunt placement. Although SVS appears to be related to early shunt placement, its predisposing factors are largely unknown. Methods. Baseline data in 737 chi... | Slitlike ventricles; Slit ventricle syndrome; Shunt insertion; Predictive factor; Ventriculoperitoneal shunt; Pediatric neurosurgery | 2007 |
| 233 |
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Couldwell, William T. | Giant fusiform aneurysm in an adolescent with PHACES syndrome treated with a high-flow external carotid artery-M3 bypass | The acronym PHACES describes a rare neurocutaneous syndrome that comprises posterior fossa malformations, facial hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, eye abnormalities, and sternal defects. Facial hemangiomas constitute the hallmark of this disorder. Giant ... | | 2007 |
| 234 |
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Couldwell, William T.; Jensen, Randy L.; Gillespie, David L. | Celecoxib inhibits meningioma tumor growth in a mouse xenograft model | Background: Treatments for recurrent meningiomas are limited. We previously demonstrated universal expression of COX-2 in meningiomas and dose-dependent growth inhibition in vitro with celecoxib, a COX-2 inhibitor. We therefore tested the effects of celecoxib on meningioma growth in a mouse xenograf... | Meningioma; Cyclooxygenase-2; COX-2; Celecoxib | 2007 |
| 235 |
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Couldwell, William T. | Total intravenous anesthesia: advantages for intracranial surgery | Although volatile anesthetics have been widely accepted in anesthetic management for neurosurgery, they reduce vascular resistance, resulting in increased cerebral blood flow and increased intracranial pressure (ICP). In patients with elevated ICP who undergo craniotomy, the increase in ICP during s... | Anesthesia; Inhalants; Intravenous; Propofol; Intracranial surgery | 2007 |
| 236 |
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Couldwell, William T. | Metastatic melanoma to the pituitary gland | Metastasis to the pituitary gland is unusual, and occurs most often in patients with carcinomas of the breast or lung. Despite its propensity for spread to the brain, metastatic melanoma has rarely been described within the sella. Methods: We report two cases of malignant melanoma pathologically co... | | 2007 |
| 237 |
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Couldwell, William T. | Comment on Aydin, K., et al: Localization of cerebrospinal fliud leaks by gadolinium-enhanced magnetic resonance cisternography: a 5-year single-center experience | The Author's describe the use of intrathecal Gd-enhanced MR cisternography for the definition of cerebrospinal fluid leaks in 51 patients. They were able to identify the site of leak in 43 of 51 patients (84%). Although the technique is not new, most of the previous articles are found in the neuror... | Cerebrospinal fluid leaks | 2007 |
| 238 |
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Couldwell, William T. | Recurrent infrasellar clival craniopharyngioma | The patient is a 44-year-old man who underwent resection of a posterior nasopharynx tumor 12 years earlier via left lateral rhinotomy approach. The final pathological analysis indicated the tumor was a craniopharyngioma, and the patient subsequently underwent focal radiation. The patient returned t... | Ectopic Craniopharyngioma; Recurrence; Infrasellar; Clivus | 2007 |
| 239 |
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Kestle, John R. W.; Brockmeyer, Douglas Lee | Evaluation of the necessity of postoperative imaging after craniosynostosis surgery | Object. Childhood radiation exposure increases the lifetime risk of cancer from an estimated 0.07 to 0.35%. Neurological evaluation of patients after cranial vault reconstruction for synostosis repair is often complicated by pain medication, sedation, intubation, swelling, and dressings; therefore c... | Computed tomography; Cranial vault reconstruction; Pediatric neurosurgery; Radiation dose; Postoperative imaging | 2007 |
| 240 |
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Couldwell, William T.; Gillespie, David L.; Jensen, Randy L. | Identification of hypoxia-induced genes in a malignant glioma cell line (U-251) by cDNA microarray analysis | Overcoming the metabolic restrictions of hypoxia may allow the progression of lower-grade tumors to glioblastoma multiforme. Our findings of up-regulation of HIF-1α and its downstream targets VEGF, GLUT-1, and CAIX in higher-grade gliomas support this hypothesis. We compared the gene expression pro... | Glioblastoma multiforme; U-251; Hypoxia; Microarray analysis; Brain tumor; Depp; Astrocytoma | 2007 |
| 241 |
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Couldwell, William T. | Response to comment on: the combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumors | We appreciate the comments by Dr. Sanna regarding our article (1). We recognize Dr. Sanna has much experience with these tumors and that, as cranial base surgeons, we should work as a team of neurosurgeons, otologists, and occasionally, head and neck surgeons and plastic surgeons. We also agree tha... | Jugular foramen tumor; Glomus jugulare tumors | 2007 |
| 242 |
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Couldwell, William T. | Comment on Kitano, M. and Taneda, M.: Extended transsphenoidal approach to the anterior communicating artery aneurysm: aneurysm incidentally identified during macroadenoma resection | Kitano and Taneda describe the successful clipping of an ACoA aneurysm via the transsphenoidal approach. There are limitations of the approach; most notable are the limited and narrow corridor and the relationship between the aneurysm and the optic chiasm, which may hinder full visualization of the ... | Aneurysm; Transsphenoidal approach | 2007 |
| 243 |
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Schmidt, Meic H. | Spinal extradural arachnoid cysts: clinical, radiological, and surgical features | Extradural arachnoid cysts in the spine are rare and are seldom a cause of spinal cord compression. They are thought to arise from congenital defects in the dura mater, and they almost always communicate with the intrathecal subarachnoid space through a small defect in the dura. The mainstay of trea... | Spinal extradural arachnoid cyst; Spinal meningeal cyst; Neurogenic claudication | 2007 |
| 244 |
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Couldwell, William T. | Resolution of an anterior-inferior cerebellar artery feeding aneurysm with the treatment of a transverse-sigmoid dural arteriovenous fistula | The authors describe a 27-year old man who developed an unruptured anterior-inferior cerebellar artery feeding aneurysm from a transverse-sigmoid dAVF and its subsequent resolution with the treatment of the dAVF. The patient, with a known history of left transverse and sigmoid sinus thrombosis, pres... | Aneurysms; Dural Arteriovenous Fistulas; Endovascular therapy; Surgery | 2007 |
| 245 |
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Schmidt, Meic H.; Apfelbaum, Ronald I. | Chylorrhea: a rare complication of thoracoscopic discectomy of the thoracolumbar junction | The thoracic duct along with the cisterna chyli is a major lymphatic pathway near the anterior thoracolumbar spine. Despite the fragile nature of the lymphatic system and its proximity to the spinal column, chylorrhea is rarely encountered by spine surgeons. The authors present a unique case of chyl... | Chylous leak; Thoracoscopy; Thoracic spine; Thoracoscopic discectomy; Thoracolumbar junction; Chylorrhea | 2007 |
| 246 |
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Couldwell, William T. | Interpositional dural graft technique for the treatment of dural arteriovenous fistulas | Dural arteriovenous fistulas (dAVFs) are acquired direct arteriovenous shunts that often drain into the dural venous sinus. Treatment options generally involve disrupting the abnormal vascular conduits by using a combination of modalities, including surgical disconnection, radiosurgery, and transar... | | 2007 |
| 247 |
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Schmidt, Meic H. | Castleman disease of the spine mimicking a nerve sheath tumor | Castleman disease is a rare lymphoproliferative disease of unknown cause. In most cases, afflicted patients present with a mediastinal mass although the disease may manifest in numerous other sites, including intracranially and rarely intraspinally. The authors report on the case of a 19-year-old wo... | Castleman disease; Nerve sheath tumor | 2007 |
| 248 |
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Kestle, John R. W. | Priorities for hydrocephalus research: report from a National Institutes of Health-sponsored workshop | Object. Treatment for hydrocephalus has not advanced appreciably since the advent of cerebrospinal fluid (CSF) shunts more than 50 years ago. Many questions remain that clinical and basic research could address, which in turn could improve therapeutic options. To clarify the main issues facing hydr... | Biomedical research | 2007 |
| 249 |
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Schmidt, Meic H. | Thoracoscopic debridement and stabilization of pyogenic vertebral osteomyelitis | The role of surgical debridement and internal fixation in treatment of vertebral osteomyelitis has been evolving. The standard surgical approach to thoracolumbar vertebral osteomyelitis requiring extensive thoracotomy or retroperitoneal exposure carries significant associated morbidity and postoper... | | 2007-01-01 |
| 250 |
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Couldwell, William T. | Conflict and opportunity: neurosurgery and industry | The relationship between neurosurgery and industry is multifaceted. Most aspects of this relationship promote the advancement of a highly technical field such as neurosurgery, helping neurosurgeons bring ever more effective therapies to their patients. However, serious ethical and legal concerns a... | | 2007-01-01 |
