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Creator | Title | Description | Subject | Date |
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Rodin, Ernst A. | Prognosis of Patients with Epilepsy | | | |
| 2 |
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Rodin, Ernst A. | Prognosis of Patients with Epilepsy | Written primarily for the physician who is responsible for the treatment of epileptic patients and the clinical investigator interested in the basic mechanisms underlying this disorder. The book also addresses itself to psychologists interested in the study of mind-brain relationships. Factors relat... | epilepsy; epileptic patients; mind-brain relationships | 1968 |
| 3 |
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Varner, Michael W.; Digre, Kathleen B. | Pseudotumor cerebri and pregnancy. | Pseudotumor cerebri (PTC) is most commonly seen in obese women of reproductive age. We studied 109 women with PTC between ages 16 and 44 years. In 11, PTC started during pregnancy. Thirteen women with previous diagnosis of PTC, including two of the aforementioned 11, had an additional 17 documented ... | Pregnancy Complications; Pseudotumor Cerebri; Vision disorders; Headache; Intracranial Pressure | 1984-06 |
| 4 |
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Varner, Michael W.; Digre, Kathleen B. | Cranial magnetic resonance imaging in eclampsia. | Although the precise neuropathologic basis for eclamptic convulsions remains unclear, intracranial hemorrhage is frequently associated with fatal cases. Magnetic resonance imaging (MRI) is a recently developed neuroimaging technique that appears superior to other processes for defining intracranial ... | Eclampsia; Brain Edema; Cranial Magnetic Resonance Imaging | 1987-09 |
| 5 |
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Digre, Kathleen B. | CT and hemifacial spasm. | Forty-six patients with typical hemifacial spasm had CT. Thirty-eight (83%) were abnormal, including two with surgically documented tumors. Thirty-six had a characteristic dolichoectatic vertebrobasilar artery, with the convexity pointing to the side of the spasm in 92% of the scans. This study sugg... | Hemifacial spasms; Tumors; Dolichoectiatic vertebrobasilar artery | 1988-07 |
| 6 |
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Digre, Kathleen B. | Significance of CT and MR findings in sphenoid sinus disease. | Disorders of the paranasal sinuses, particularly the sphenoid sinus, can be associated with significant disorders of the optic and other cranial nerves. We examined 100 consecutive routine CT scans, 100 posterior fossa CT scans, and 100 MR scans to look for evidence of sinus disease, especially of t... | Sphenoid Sinus; Vision Disorders; Paranasal Sinus Diseases; Magnetic Resonance Imaging | 1989-05 |
| 7 |
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Jaeckle, Kurt A.; Digre, Kathleen B.; Jones, Christopher R.; Bailey, Peter L. | Central neurogenic hyperventilation: pharmacologic intervention with morphine sulfate and correlative analysis of respiratory, sleep, and ocular motor dysfunction. | Central neurogenic hyperventilation (CNH), for which there is no effective therapy, can eventually result in respiratory fatigue and death. This report describes a patient with CNH due to a brainstem anaplastic astrocytoma who also exhibited disturbances of sleep and ocular motor function. The CNH r... | Central Neurogenic H yperventilation; Ocular Motor Dysfunction | 1990-11 |
| 8 |
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Digre, Kathleen B. | Selective MR imaging approach for evaluation of patients with Horner's syndrome. | PURPOSE: To assess the usefulness of MR in the evaluation of patients with Horner's syndrome. PATIENTS AND METHODS: We prospectively performed MR imaging in 33 patients with Horner's syndrome (13 preganglionic and 20 postganglionic) using a protocol specifically designed for pre- and postganglionic ... | Horner Syndrome; Magnetic Resonance Imaging; Epidemiology | 1992-01 |
| 9 |
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Digre, Kathleen B.; Skuster, Denise Z. | Neurologic conditions presenting as psychiatric disorders. | Understanding underlying neuroanatomic function helps physicians to localize defects and search for treatable neurologic conditions. Neurologic conditions such as Huntington's chorea, Wilson's disease, Gille de la Tourette syndrome, brain tumors, encephalitis and meningitis, neurodegenerative condit... | Psychiatric Diagnosis; Neurologic Disease | 1992-06-15 |
| 10 |
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Kriesel, John D.; Baringer, J R; Spruance, Spotswood L. | Correlation between detection of herpes simplex virus in oral secretions by PCR and susceptibility to experimental UV radiation-induced herpes labialis. | We examined the oral secretions of 25 patients for herpes simplex virus (HSV) at the time of and following experimental UV radiation (UVR). HSV was detected in one or more oral secretion specimens in 5 of 12 (42%) cases by cell culture and in 8 of 12 (67%) cases by PCR. On the day of UVR, HSV was de... | Polymerase Chain Reaction; Ultraviolet Rays; Simplexvirus | 1994 |
| 11 |
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Digre, Kathleen B.; Gouw, Launce G.; Harris, Catherine P.; Haines, John H.; Ptacek, L.J. | Autosomal dominant cerebellar ataxia with retinal degeneration: clinical, neuropathologic, and genetic analysis of a large kindred. | The autosomal dominant cerebellar ataxias (ADCA) comprise a heterogeneous group of neurologic disorders characterized by degeneration of the cerebellum, spinal cord, and brainstem. Genetic analysis has revealed two loci, SCA1 on chromosome 6p, and SCA2 on chromosome 12q, responsible for some ADCA. W... | Retinal Degeneration; Cerebellar Ataxia; Genetic Analysis | 1994-08 |
| 12 |
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Kriesel, John D.; Maulden, Sarah Annamarie; Spruance, Spotswood L. | Anti-interleukin-6 antibodies inhibit herpes simplex virus reactivation. | Herpes simplex viruses (HSVs) infect epithelial cells, become localized in neurons, and can reactivate in response to a variety of stimuli, including ultraviolet light and hyperthermia. The sequence of gene activation during viral replication is known, but the molecular linkage between exogenous sti... | Mice, Inbred BALB C; Tumor Necrosis Factor-alpha; Virus Activation | 1997 |
| 13 |
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Gouw, Launce G.; McKenna, Catherine K.; Digre, Kathleen B.; Placek, Louis J. | Analysis of the dynamic mutation in the SCA7 gene shows marked parental effects on CAG repeat transmission. | The gene for spinocerebellar ataxia 7 (SCA7) includes a transcribed, translated CAG tract that is expanded in SCA7 patients. We have determined expansions in 73 individuals from 17 SCA7 kindreds and compared them with repeat lengths of 180 unaffected individuals. Subjects with abnormal expansions co... | Genetics; Biosynthesis; SCA7 Gene | 1998-03-07 |
| 14 |
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Swallow, Charles E.; Tsuruda, Jay S.; Digre, Kathleen B.; Glaser, Matthew J.; Davidson, H. Christian; Harnsberger, H. Ric | Terson syndrome: CT evaluation in 12 patients. | PURPOSE: Terson syndrome may be overlooked in the acute setting and often requires ophthalmologic intervention to prevent long-term visual loss. In this syndrome, vitreous or retinal hemorrhage results from an abrupt rise in intracranial pressure, leading to retinal venous hypertension and intraocul... | Retinal Hemorrhage; Visual Acuity; Vitreous Hemorrhage | 1998-04 |
| 15 |
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Jones, Bryan W.; Jones, Christopher R.; Czajkowski, Laura | Familial advanced sleep-phase syndrome: a short-period circadian rhythmvariant in humans | Biological circadian clocks oscillate with an approximately 24-hour period, are ubiquitous, and presumably confer a selective advantage by anticipating the transitions between day and night. The circadian rhythms of sleep, melatonin secretion and body core temperature are thought to be generated by ... | Activity Cycles; Matched-Pair Analysis; Polysomnography | 1999 |
| 16 |
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Digre, Kathleen B. | Novel mechanism for benign essential blepharospasm. | PURPOSE: The purpose of this study is to test the hypothesis that the photophobia of benign essential blepharospasm (BEB) is caused by sympathetically maintained pain. METHODS: Nineteen patients with photophobia and BEB were enrolled in an unblinded prospective treatment trial. The intervention was ... | Blepharospasm, Autonomic Nerve Block, Blepharospasm, Superior Cervical Ganglion, Lidocaine, Pain | 1999-11-15 |
| 17 |
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Digre, Kathleen B.; Kleinschmidt, Julia J.; Hanover, Rita | Idiopathic intracranial hypertension. Relationship to depression, anxiety, and quality of life | OBJECTIVE: To explore the incidence of depression and anxiety and to measure quality of life in women with idiopathic intracranial hypertension (IIH), a matched group cross-sectional study was conducted. Women with IIH (n = 28) were compared with control groups of weight- and age-matched women not d... | Intracranial Hypertension; Depression; Anxiety; Quality of Life | 2000-01-25 |
| 18 |
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Bernstein, Paul S.; Zabriskie, Norman A.; Zhang, Kang; Leppert, Mark F. | Diverse macular dystrophy phenotype caused by a novel complex mutation in the ELOVL4 gene | PURPOSE: A 5-bp deletion in ELOVL4, a photoreceptor-specific gene, has been associated with autosomal dominant (ad) macular dystrophy phenotypes in five related families, in which phenotypes range from Stargardt-like macular dystrophy (STGD3; Mendelian Inheritance in Man 600110) to pattern dystrophy... | Linkage (Genetics); Middle Older people; Phenotype | 2001 |
| 19 |
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Digre, Kathleen B.; Schmidt, Richard H.; Osborne, Anne G.; Patel, Bhupendra C.; Pratt, David; Rietz, Lisa A. | Compressive optic neuropathy caused by renal osteodystrophy. Case report. | Compressive optic neuropathy with acute or chronic vision loss has been associated with various skull base tumors, aneurysms, Graves disease, trauma, and, less commonly, fibrous dysplasia and osteopetrosis. The Author's present a case of acute visual deterioration in a 25-year-old woman who had mass... | Optic Neuropathy; Optic Nerve Decompression; Renal Osteodystrophy | 2001-10 |
| 20 |
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Bernstein, Paul S.; Leppert, Mark F. | Genotype-phenotype analysis of ABCR variants in macular degeneration probands and siblings | PURPOSE: Single-copy variants of the autosomal recessive Stargardt disease (STGD1) gene ABCR (ABCA4) have been shown to confer enhanced susceptibility to age-related macular degeneration (AMD). To investigate the role of ABCR alleles in AMD further, genotype-phenotype analysis was performed on sibli... | DNA Mutational Analysis; Nuclear Family; Phenotype | 2002 |
| 21 |
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Digre, Kathleen B. | Not so benign intracranial hypertension. | Despite many controversies, intracranial hypertension due to use of doxycycline does occur. Practitioners prescribing the tetracyclic antibiotics should be aware of the syndrome of increased intracranial pressure, and pay particular attention to the ocular fundus for papilloedema. Appropriate referr... | Venous Occusion; Venous Hypertension; Tetracycline, Doxycycline; Minocycline | 2003-03-22 |
| 22 |
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Singleton, J. Robinson; Smith, A. Gordon | Microvascular complications of impaired glucose tolerance. | Impaired glucose tolerance (IGT) serves as a marker for the state of insulin resistance and predicts both large- and small-vessel vascular complications, independent of a patient's progression to diabetes. Patients with IGT are at significantly increased risk for death and morbidity due to myocardia... | Microcirculation; Humans | 2003-12-01 |
| 23 |
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Levy, James A. | Context-specific memory and apolipoprotein E (ApoE) epsilon 4: cognitive evidence from the NIMH prospective study of risk for Alzheimer's disease. | The aim of the study was to determine whether the epsilon 4 allele of the apolipoprotein E (ApoE) gene was associated primarily with context-specific memory among individuals at genetic risk for developing Alzheimer's disease. The effect of ApoE status on comprehensive neuropsychological results was... | Alleles; Apolipoprotein E4; Mental Status Schedule | 2004-05-10 |
| 24 |
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Foster, Norman L. | Novel insertional presenilin 1 mutation causing Alzheimer disease with spastic paraparesis. | A four-generation pedigree exhibiting early-onset autosomal dominant Alzheimer disease (AD) with spastic paraplegia, dystonia, and dysarthria due to a novel 6-nucleotide insertional mutation in exon 3 of the presenilin 1 gene (PS1) is described. Serial examinations, PET scans, and autopsy revealed t... | Older people, 80 and over; Membrane Proteins; Neuropsychological Tests | 2004-05-25 |
| 25 |
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Smith, A. Gordon; Singleton, J. Robinson | Lifestyle intervention for pre-diabetic neuropathy. | OBJECTIVE: The purpose of this study was to evaluate intraepidermal nerve fiber density (IENFD) as a sensitive measure of neuropathy change in patients with neuropathy associated with impaired glucose tolerance (IGT) receiving lifestyle intervention based on that used in the Diabetes Prevention Prog... | Older people; Biopsy; Blood Pressure; Body Mass Index; Cholesterol; Diabetic Diet | 2006-06-29 |
