| Title | Author | Subject | Description | Date | ||
|---|---|---|---|---|---|---|
| 1 | In vivo and in vitro effects of phenytoin on anion and cation transport systems of the rat brain | White, Harold Steve | Physiology; Rats | Various parameters of anion and cation transport were measured in the cerebral cortex of neonatal (3 days old) and adult rats following acute and chronic treatment with PHT. Acutely, phenytoin (PHT) significantly inhibited the enzyme Na+, K+-ATPase in both neonatal and adult rats. This effect was ac... | 1984-03 | |
| 2 | Effect of cycloheximide treatment on the mixed-function oxidase system of rat liver | Williams, Joseph Francis | Metabolism; Drugs; Cycloheximide; Rats | The effect of cycloheximide treatment on the mixed-function oxidase system of rat liver was studied at 12 and 24 hours after administration of the antibiotic. Protein synthesis was inhibited in the animals for the 24-hour experimental period with the maximal tolerable dose, 2 mg/kg. Cycloheximide... | 1971-06 | |
| 3 | The diurnal variation of norepinephrine in the rat parotid gland | Soderberg, Robert Carl | Laboratory Animals; Rats | The parasympathetic and sympathetic nervous systems are both involved in the control of secretion of the major salivary glands although the parasympathetic system is more dominant. Previous work by Sreebny and Johnson (1969) has demonstrated a diurnal variation in three secretory enzymes of the rat... | 1972-06 | |
| 4 | Effects of penicillin pretreatment on renal tubular para-aminohippurate transport in the immature rat | Noordewier, Byron | Rats; Physiology | The effect of pretreatment with penicillin on para-aminohippurate (PAH) transport by kidney of the immature rat was evaluated in vivo. After 3 days of penicillin administration, the renal clearances of inulin (CIN), PAH(CPAH), and N-methylnicotinamide (CNMN) and the rental tubular transport maximu... | 1976-08 | |
| 5 | Effects of oral cyclosporine and cremophor-EL on microvascular dynamics and the barrier function of skin in the nude rat. | Jederberg, Warren William | Skin Absorption; Rats | Studies were conducted to asses the impact of the oral administration of cyclosporine and cremophor-EL on parameters important to the per-cutaneous penetration of compounds through nude rat skin. The two parameters chosen were dermofluorometric response to injected fluorescein (reflecting vasculari... | 1987-08 |